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Aim: We aimed to study the feasibility and tolerability of a combination therapy consisting of glutamic acid decarboxylase (GAD-alum), Etanercept and vitamin D in children and adolescents with newly diagnosed with type 1 diabetes (T1D), and evaluate preservation of beta cell function. Material and Methods: Etanercept Diamyd Combination Regimen is an open-labelled multi-centre study pilot trial whi
In recent years the number of connected devices and the demand for high data-rates have been significantly increased. This enormous growth is more pronounced by the introduction of the Internet of things (IoT) in which several devices are interconnected to exchange data for various applications like smart homes and smart cities. Moreover, new applications such as eHealth, autonomous vehicles, and c
We live in a world built on consumerist values and a spatial rationale of capital accumulation. This modern society has led to architecture thriving through super consumption and super production ultimately leading to the generic. Cities and spaces that were usually rich in variation and texture have now become an architectural melting pot. Architecture has become smooth, simplified and reduced to
Cua Lo river mouth is a coastal inlet connected to an estuary at the central coast of Vietnam. The area is valuable for maritime trade, fishing industries, and tourism development. Natural disasters during the monsoon period are a problem, causing seasonal flooding. In connection to the inlet lies an elongating sand spit which causes erosion and destruction of residential areas on one side of the
Egyptology in the 19th and early 20th centuries developed simultaneously with increased imperial presence in Egypt by the European imperial powers, which would have influence on how the discipline was practised. The history of Egyptology has for this reason primarily focused on the big four – Great Britain, France, Germany and USA – and on Egypt itself. The aim of this study is to examine how Egyp
Delivery of goods at the port of discharge is an obligation incurred upon the carrier under a contract of carriage by sea. The extent of the carrier’s obligation is to give the consignee a reasonable time to take proper delivery of the goods against presentation of an original B/L. Delivery of goods is currently not regulated in any international laws on carriage of goods by sea, it is only regula
Summary Title: How to make decisions on software based service development in the mobile handset industry. –The Rapid Model for Holistic Application Evaluation Authors: Per-Inge Andersson Patrik Dreveborn Tutors: Björn Regnell, Department of Computer Science, Lund University Robert Wenglén, School of Economics and Management, Lund University Problem formulation: Academically the questions of findi
In Alzheimer’s disease (AD), β-amyloid and tau accumulate in the brain leading to neuronal loss and cognitive decline. The associations between these protein aggregates and their downstream effects are clear but not perfect, with other, largely unknown, factors explaining the discrepancy. This phenomenon has been described within the resilience framework.We aimed to explore whether demographic fac
Structural and mechanistic aspects of orthoplatination of acetophenone and benzaldehyde oximes by the platinum(II) sulfoxide and sulfide complexes [PtCl2L2] (2, L = SOMe2 (a), rac-SOMePh (b), R-SOMe(C6H4Me-4) (c), and SMe2 (d)) to afford the corresponding platinacycles cis-(CS)-[Pt-II(C6H3-2-CR'=NOH-5-R)CI(L)] (3, R, R' = H, Me) have been investigated. The reaction of acetophenone oxime with sulfo
Context. The ESA space astrometry mission Gaia, planned to be launched in 2013, has been designed to make angular measurements on a global scale with micro-arcsecond accuracy. A key component of the data processing for Gaia is the astrometric core solution, which must implement an efficient and accurate numerical algorithm to solve the resulting, extremely large least-squares problem. The Astromet
Background: The rate of biological ageing is individual and represents the steady decrease in physiological and mental functions. Adverse social factors have been shown to influence this process. Self-perceived early ageing (SEA) might be a useful indicator of early biological ageing and increased mortality risk. The aim of this population-based study was to identify markers of SEA, including telo
Abstract in Undetermined We present an efficient method for importance sampling the product of multiple functions. Our algorithm computes a quick approximation of the product on the fly, based on hierarchical representations of the local maxima and averages of the individual terms. Samples are generated by exploiting the hierarchical properties of many low-discrepancy sequences, and thresholded ag
En ökad efterfrågan på miljövänliga energialternativ har resulterat i att allt fler länder börjat utvärdera sina geotermala tillgångar. En bidragande orsak till det ökade geotermala intresset är förändrade krav som ställs på geologin och hydrologin med dagens moderna EGS-anläggningar. Med EGS-tekniken (Enhanced Geothermal Systems) skapar man idag konstgjorda reservoarer, för fjärrvärme- och elprodThe increasing demand for eco-friendly energy alternatives and the changing requirements of state of the art EGS-plants (Enhanced Geothermal Systems) have set the mark for many countries to start evaluating their geothermal assets. By using the EGS-technique, artificial reservoir providing district heating and electricity are created around the world by stimulating the bedrock hydrostatically with
A patient who comes up against a bodily injury due to medical care, may be entitled to compensation - but the legal requirements in order to recieve compensation diversifies with the cause of damage. PSL comprises certain circumstances and identifies situations under which a patient may be entitled to insurance based indemnification. SKL is generally applicable on questions of pain-and-suffering a
År 1926 färdigställde Processkommissionen sitt principbetänkande angående rättegångsbalkens ombildning. Kommissionen föreslog en form av förenklat förfarande, där enklare mål skulle kunna lagföras utanför domstolen. Den största anledningen till att ett enklare och snabbare förfarande ansågs behövas var för att avlasta domstolarna från en allt för tung arbetsbörda. Snabbspolat framåt, så reglerasIn 1926 a commission report about a new code of judicial procedure was completed. The commission suggested the introduction of a summary procedure for misconducts that did not need to be resolved by the court. The main reason for this procedure was that it would unburden the courts from a heavy workload. Fast forward to today, the summary procedure, penal order, is regulated in chapter 48 of the
In this article we argue the need for more socio-legal scrutiny in a digitally mediated and data-driven development. We focus and briefly outline socio-legally relevant aspects of the “sharing” economy, that poses a number of conceptual issues on how we understand and regulate innovative platform based ventures. This also arguably underscores a number of issues relating to the role of consumer and
This dissertation investigates the labour migration from Southern Europe to Sweden, and the changes in Swedish immigration policy between 1960 and 1972. The overall ambition is to bring both the state and employers into the analysis of immigration policy and the recruitment of foreign labour - not separately but together in one study. The dissertation is divided into two main parts. The first part
Rationale: A microdeletion at locus 15q13.3 is associated with high incidence rates of psychopathology, including schizophrenia. A mouse model of the 15q13.3 microdeletion syndrome has been generated (Df[h15q13]/+) with translational utility for modelling schizophrenia-like pathology. Among other deficits, schizophrenia is characterised by dysfunctions in prefrontal cortical (PFC) inhibitory circu
