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Combined structural methods to characterize an oligomeric small heat shock protein Hsp21

Undersökning av Hsp21 med korslänknings-masspektrometriMänniskans kropp består av ungefär 30 trillioner celler och varje cell innehåller omkring 100 000 proteiner. Föreställ dig om kroppen vore jordklotet, varje vävnad ett land och varje cell en stad. Varje stad vore då konstant som Paris i rusningstrafiken. Trafiken vore helt galen hela tiden och väldigt känslig för även den minsta störning. CellSmall heat shock proteins (sHsps) are found in all organisms and evolved early in the history of life, prior to the divergence of the three domains of life (Archaea, Bacteria, and Eukarya). Their malfunction is connected to several different diseases in humans, such as Alzheimer’s and Parkinson’s disease. sHsps are especially abundant in plants, where most are highly upregulated as the first line

Tryckt bild eller avbildat tryck? : Visuella representationer av begrepp relaterade till tryck i fysikläroböcker för högstadiet

AbstractIn this study visual representations of the concept of pressure in five physics textbooks for lower secondary school have been analysed in terms of how they communicate the concept of pressure, and also how these representations work together to explain what pressure is. Examples of visual representations are fonts, photographs, sketches, tables or mathematic formulas. The analysis will an

Characteristics of Particle Emissions at Paint Manufacturing

The handling of pigments and powders in paint manufacturing cause emissions of airborne particles. A great variety of substances occur. Previous studies (Bohgard et al., 1994) of simulations of pouring of pigments, which occur in small scale weighing procedures, showed typically bimodal size distribution including a sub-micron and a super-micron mode.The objective of the study was to get detailed

The parents school? Narrative research about parental involvement

Popular Abstract in Swedish Föräldrars involvering i skolan har under de senaste decennierna betonats allt mer i skoldebatten. Länge betraktades skolutbildning som enbart ett samhälleligt ansvar, vilket ofta medförde ett markerat avståndstagande från familjen och föräldrarna. Likt andra samhälleliga servicefunktioner har emellertid också skolan i sitt förhållande till sina användare undergått en fOver the last two decades, educational reforms have stimulated an enormous growth in innovative school thinking, effecting both independent schools and mainstream education. Parents and interest groups, previously excluded from general pedagogic practice and planning, are now faced with new opportunities and responsibilities. Parents “invest” in these newly won options in very different ways. Fail

A Profession in Transformation: The paradox of industrial and design in a post-industrial society

It is argued that we live in a post-industrial society with a transition from the production of goods to services. It is also said we live in a knowledge economy where creation, distribution, use and manipulation of information are significant activities (Dahlbom, 2003). The word industrial has a connotation of mass-production of products and, logically also industrial design has this connotation.

Self-regulation versus State Regulation in Swedish Industrial Relations

The Swedish model of industrial relations is distinguished by a high degree of self-regulation with roots around the turn of the century 1900. Under the threat of state regulation, the labour market parties in the 1930s, and again in the late 1990s, found they had a common interest in self-regulation. The 1938 Saltsjöbaden Agreement between the blue-collar confederation LO and the employer confede

Getting hard to resist: Prospect of mandatory human rights due diligence in Ukraine

The 2011 UN Guiding Principles on Business and Human Rights (UNGPs) introduced human rights due diligence (HRDD) as a societal expectation to businesses to implement a new kind of due diligence risk management process to ‘know and show’ they respect human rights. Ten years later, mandatory human rights due diligence (mHRDD) legislation imposing a legal duty to carry out HRDD has become mainstream

Om emittenters hantering av insiderinformation vid due diligence-undersökningar

När ett bolag vill lägga ett offentligt uppköpserbjudande på ett noterat målbolag så är det vanligt att det köpande bolaget vill ha tillgång till viss information om målbolaget för att kunna bedöma målbolagets attraktivitet. En sådan undersökning kan omfatta finansiella, kommersiella och legala aspekter av målbolaget. Vad som undersöks beror till stor del av vad den potentiella köparen är intresseWhen a company wants to acquire a publicly traded company, it must do so by launching a takeover bid. The takeover is usually done in several steps, one of them being the due diligence. The due diligence is done to evaluate the attractivity of the target company as well as the risks of the takeover. What the due diligence investigates may depend on the key interests of the potential buyer, but can

Inglasade balkonger - Definitioner och möjligheter

This report is about glazed balconies and intends to answer following questions: • Does glazed balconies have a “grey area” – i.e. is it free for interpretation? • Are better definitions for glazed balconies and its aspects needed? • Can our research expand the possibilities with glazed balconies from an aesthetic and practical view? The report will be processing different types of definitions and

Säker köttbullsproduktion

The Swedish legislation regulates that food producers provide safe food from a microbiological perspective. One way to ensure the foods´ quality, is to control the microbiological levels by combining the measures of different time durations and temperatures during cooking. The elimination of microorganisms in food depends on both temperature and time. The higher the temperature, the shorter the ti

Frihetsberövad på misstanke - Om häktningens funktion i straffprocessrätten

Om ett brott som hör under allmänt åtal har begåtts ska förundersökning inledas och bedrivas i syfte att ta fram material som gör det möjligt för åklagaren att fatta beslut i åtalsfrågan. Till sin hjälp att bedriva en effektiv utredning har polis och åklagare möjlighet att använda straffprocessuella tvångsmedel. De straffprocessuella tvångsmedlen ger polis och åklagare rätt att använda åtgärder soIf an offense subject to public prosecution has been committed a preliminary investigation shall be initiated and carried out in order to optain materials to make it possible for the prosecutor to decide on the prosecution issue. To assist the police and prosecutors to conduct an effective investigationt they have the option of using coercive measures. The coercive measures give police and prosecu

Exploring Environmentally Sustainable Last-Mile Deliveries in Sweden

Last-mile delivery is the part of the e-commerce supply chain that is the least efficient in terms of cost, time, and environmental impact. As e-commerce is expected to keep growing, this puts pressure on last-mile deliveries to reduce their environmental impact if Sweden is to reach its environmental goals for 2045. E-retailers in Sweden are offering their customers a selection of last-mile deliv

Load following in a Swedish nuclear power plant

Det svenska energisystemet är under ständig utveckling. Länge har vatten- och kärnkraft varit grundstenarna i energiproduktionen, där kärnkraft utgjort den så kallade baslasten och vattenkraften reglerkraften. Då allt mer väderberoende vindkraftverk byggs förändras förutsättningarna för det svenska energisystemet, där en stor del av elproduktionen blir allt mer oförutsägbar på grund av variationerThe energy system in Sweden is currently under a great transformation, where the part of weather dependent energy sources, so called intermittent sources, like solar and wind power will get greater share in the total production of electricity while the production from stable energy sources like nuclear power is decreasing. For a long time, the nuclear power have been operating at baseload and the

Kreativitet och undervisningsmetoder - om rutiner och kaos inom institutioners ramar

Sammanfattning Detta arbete handlar om att kritiskt belysa de aspekter av undervisning som är centrala för mig som pedagog. Som lärare vill jag nå fram till eleven, jag vill att eleven ska ha möjligheten att vara kreativ och att få uppleva det tillstånd som kallas flow. Arbetet har utgått från de upplevelser jag fick av musik när jag var yngre, då tänkte jag inte i termer och begrepp utan upplev

The protection of migrant women subjected to domestic violence under the framework of the Council of Europe. A feminist approach

Migrant women facing domestic violence in the Council of Europe have been traditionally characterised, except in some national countries, as not having any legal possibility to leave the situation with proper resources, or being able to guarantee their stay in the country they are living. Since the approval of the Council of Europe Convention on preventing and combating violence against women and

A model for mapping carbon dioxide emissions during freight transports at Höganas AB, Sweden

The purpose of this report is to develop a model that identifies and reveals the total carbon dioxide emissions generated throughout in- and outbound freight transport made by Höganäs Sweden. The developed model is to be used for future environmental calculations and also act as a tool for discovering new areas of environmental improvements. During the developing process of the model a key issue

Implementation of Simulators at Sandvik Chile – “Practice Makes Perfect”

With a current financial crisis and a tough competitive environment, all units and departments within the companies have to keep up with the market and its demands. Every time Sandvik sells a machine to a mining company, the buyer faces the fact that they normally have to educate their operators from scratch. This, implicitly, means a period with high risks of failures and mistakes. Training with

Taking product replacement decisions by means of the Analytic Hierarchy Process

In an economic environment signified by shortened product lifecycles, product proliferation and reduced profit margins, product replacement decision making (PRDM) ought to be an important part of management. The case is however often that considerably more energy and resources at a firm are spent at the opposite task, hence product development. The main purpose of this master thesis was to constru

Screening Detected Celiac Disease in Children

Popular Abstract in Swedish Bakgrund och syfte med avhandlingen Glutenintolerans, celiaki är en av de vanligaste kroniska sjukdomarna bland barn och innebär att man inte tåler gluten, som är ett protein och finns i vete, råg och korn. Tunntarmen har en veckad slemhinna med fingerlika utskott , tarmludd och hela tarmen har en yta på 250 kvadratmeter, vilket är lika stort som en tennisplan. Den stBackground: The prevalence of celiac disease (CD) is estimated to be around 1%, but most CD cases are undiagnosed. Sweden experienced an epidemic of clinically detected celiac disease in children younger than 2 years of age, partly due to changes in infant feeding practices, were the amount of gluten and age at introduction was changed. However, it was not clear if the increase in clinically detec