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Popular Abstract in Swedish Proteinkinas C i nervcellsutveckling Under fosterutvecklingen ska en enda cell, den befruktade äggcellen, ge upphov till alla de högt specialiserade celler som människokroppen består av. Den process där omogna celler utvecklas till t.ex. nervceller, blodceller och muskelceller kallas differentiering. Det som avgör vad en speciell cell ska utvecklas till är bl.a. vilka sThe human neuroblastoma cell line SH-SY5Y can be induced to differentiate into a neuronal sympathetic phenotype after treatment with 16 nM 12-O-tetradecanoyl phorbol 13-acetate (TPA) in serum, or by a combination of the growth factors basic fibroblast growth factor and insulin-like growth factor-I (bFGF/IGF-I). SH-SY5Y cells stably transfected with TrkA, the nerve growth factor (NGF) receptor, dif

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Policy documents are part of university’s positioning within national and globalized negotiations. Who is written in as belonging to academia, and how do we describe and ascribe belonging? Since 2011 Lund University has an integrated policy for gender equality, equal treatment and diversity work. With this text, I analyze this policy and related documents to understand which meanings are attached

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Sustainability, resilience and safety are features of a society that are more affected by sound environments than is generally acknowledged, even if other environmental threats may appear more prominent. But when noise levels reach the limits of sustainability in society, it´s resilience to destructive processes of many kinds will be challenged. In an interdisciplinary symposium in 2014 arranged b

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C3 and C5 convertases are central stages of the complement cascade since they converge the different initiation pathways, augment complement activation by an amplification loop and lead to a common terminal pathway resulting in the formation of the membrane attack complex. Several complement inhibitors attenuate convertase formation and/or accelerate dissociation of convertase complexes. Functiona

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Popular Abstract in Swedish Avhandlingen består av tre delar. Den första, Från utbildningsmarknad till of-fentlig utbildning. Svensk flickskola 1874-1962, behandlar dels integrationen av flickornas sekundärutbildning i den offentliga utbildningsorganisationen, dels förstärkningen respektive försvagningen av denna speciellt genuskodade utbild-ning. Sekundärutbildningen har varit könssegregerad och The thesis is divided into three sections. The first, “From an education market to public education. The Swedish girls’ school 1874-1962”, deals with the integration of girls’ secondary education into the public education system, as well as with the strengthening and weakening of this special, gender-coded education. Secondary education was gender segregated and integration involved a process of s

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We present the results of dynamic in-situ 3D X-ray imaging of methane hydrates microstructure during methane hydrate formation and dissociation in sand samples. Short scanning times and high resolution provided by synchrotron X-rays allowed for better understanding of water movement and different types of gas-hydrate formation. Complementing previous observations, we conclude that the process of g

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Hidden Markov models are applied in many expert and intelligent systems to detect an underlying sequence of persistent states. When the model is misspecified or misestimated, however, it often leads to unrealistically rapid switching dynamics. To address this issue, we propose a novel estimation approach based on clustering temporal features while penalizing jumps. We compare the approach to spect

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Mainstream option valuation theory relies implicitly on the assumption that latent states (such as stochastic volatility) and parameters are perfectly known, an assumption that is dubious in many ways. Computing the value of options under the assumption of perfect knowledge will typically introduce bias. Correcting for the bias is straightforward but can be computationally expensive. Fourier-base

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The photoionization of xenon atoms in the 70–100 eV range reveals several fascinating physical phenomena such as a giant resonance induced by the dynamic rearrangement of the electron cloud after photon absorption, an anomalous branching ratio between intermediate Xe+ states separated by the spin-orbit interaction and multiple Auger decay processes. These phenomena have been studied in the past, u

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Aims: To describe and compare perceptions of collaboration between care providers on the part of three groups of Registered Nurses working in municipal care and having particular responsibility concerning the care of frail older people with intellectual disability (ID); and, furthermore, to investigate the presence of and compliance with guidelines for the coordination of care. Design: National su

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The TRE3 research project focuses on the development of a new and innovative timber frame wall modulus for emergency housing facilities. The wall modulus, in this paper referred to as Hybrid Timber Frame (HTF) wall system, is an evolution of the traditional Light-Frame Timber (LFT) structural systems and combines the advantages and some peculiar aspects of lightweight structures to the potentialit

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Heterogeneous patterns of genomic differentiation are commonly documented between closely related populations and there is considerable interest in identifying factors that contribute to their formation. These factors could include genomic features (e.g., areas of low recombination) that promote processes like linked selection (positive or purifying selection that affects linked neutral sites) at

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The European Union plays a globally influential role in environmental legislation, with policies and regulation rooted in particular norms. Through a narrative on regulatory capitalism, ecological modernization, and diffusion, we trace how the promotion of renewable energy in transport through subsidies, mandatory targets, and prescriptive criteria for liquid biofuels mobilize social forces for itThe European Union plays a globally influential role in environmental legislation, with policies and regulation rooted in particular norms. Through a narrative on regulatory capitalism, ecological modernization, and diffusion, we trace how the promotion of renewable energy in transport through subsidies, mandatory targets, and prescriptive criteria for liquid biofuels mobilize social forces for it

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Expansions of innovation policies have been paralleled with an increase in the evaluations of such policies. Yet, there are few systematic evaluations of how such evaluations are conducted, by whom, and their overall conclusions. We analyze 110 evaluations of innovation policy in Sweden from 2005 to 2019. Our findings show that the majority of these evaluations are positive, about one-third are neExpansions of innovation policies have been paralleled with an increasein the evaluations of such policies. Yet, there are few systematic evaluations of how such evaluations are conducted, by whom, and their overall conclusions. We analyze 110 evaluations of innovation policy in Sweden from 2005 to 2019. Our findings show that the majority of these evaluations are positive, about one-third are neu

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Efficient and robust control strategies can greatly contribute to the reliability of fuel cell systems, and a stable output voltage is a key criterion for evaluating a fuel cell system's reliability as a power source. In this study, a polymer electrolyte fuel cell (PEFC) system model is developed, and its performances under different operating conditions are studied. Then two different novel contr

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Although the two active redox centers in Li-rich cathodes, including the anionic and cationic contributions, can enable Li-ion batteries to achieve outstanding specific energy, their behaviors at different current densities have not been clarified. Here, we provide a comparative study of transition metals (TMs) and oxygen redox activities by directly accessing their oxidation states in Li-rich mat

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Bacterial extracellular vesicles (EVs) contain numerous active substances that mediate bacterial interactions with their host and with other microbes. Best defined are the EVs from Gram-negative bacteria that have been shown to deliver virulence factors, modulate the immune responses, mediate antibiotic resistance, and also inhibit competitive microbes. Due to the complex cell wall structures of G

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The chiral bile salt sodium cholate has been covalently linked to tetra-aryl-porphyrins, conferring them an extrinsic chirality and obtaining new molecules with high tendency to aggregate in solution. The chirality transfer from the molecular to the nano- and meso-scale has been investigated by promoting the self-assembly of the conjugates balancing the ratio of aqueous/organic solvent mixtures an