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Type 2 diabetes (T2D) is a common metabolic disease and its prevalence is increasing worldwide. Adipose tissue plays an important role in metabolic processes. Environmental factors may affect metabolic phenotypes and epigenetics may mediate this influence. We used Illumina 450k microarrays to study correlations between epigenetic patterns in human adipose tissue and environmental factors such as h
The interest in diffusion imaging with nuclear magnetic resonance techniques has increased during the last few years. The main reason is the possibility of early diagnosis of acute ischaemic stroke, at a time when conventional MR techniques and computerised tomography fail. The purpose of this study was to develop and evaluate methods for the measurement of water self-diffusion in vivo usin
Background: Processing the surface electromyogram (sEMG) to decode movement intent is a promising approach for natural control of upper extremity prostheses. To this end, this paper introduces and evaluates a new framework which allows for simultaneous and proportional myoelectric control over multiple degrees of freedom (DoFs) in real-time. The framework uses multitask neural networks and domain-
Carbon sequestration is an essential ecosystem service (ES) for climate change mitigation. For reasons of simplicity this ES is often quantified considering carbon storage in four carbon pools: aboveground biomass, belowground biomass, dead organic matter and soil organic carbon. Indicators of these four pools are estimated by modelling, reference values, or field methods and data processing of di
Environmental loads, such as wind and river flow, play an essential role in the structural design and structural assessment of long-span bridges. Climate change and extreme climatic events are threats to the reliability and safety of the transport network. This has led to a growing demand for digital twin models to investigate the resilience of bridges under extreme climate conditions. Kalix bridg
Ojämlikhet, i termer av hur resurser fördelas mellan olika kategorier av människor, är ett genomgripande samhällsfenomen. Den svenska arbetsmarknaden är inget undantag och uppvisar en betydande grad av klassad, etnifierad och könad ojämlikhet när det gäller tillgång till kontroll och makt över produktionsförhållanden. Denna avhandling syftar till att bidra med kunskap om hur och varför ojämlikhetsInequality, in terms of how resources are distributed between different categories of people is a pervasive phenomenon in society. The Swedish labour market is no exception, exhibiting a significant degree of classed, ethnified and gendered inequality in terms of access to control and power over production conditions. This thesis aims to contribute knowledge about how and why inequality regimes ar
The European Congenital Heart Surgeons Association (ECHSA) Congenital Database (CD) is the second largest clinical pediatric and congenital cardiac surgical database in the world and the largest in Europe, where various smaller national or regional databases exist. Despite the dramatic increase in interventional cardiology procedures over recent years, only scattered national or regional databases
The European Congenital Heart Surgeons Association (ECHSA) Congenital Database (CD) is the second largest clinical pediatric and congenital cardiac surgical database in the world and the largest in Europe, where various smaller national or regional databases exist. Despite the dramatic increase in interventional cardiology procedures over recent years, only scattered national or regional databases
In this study, we modeled the aerosol particle formation along air mass trajectories arriving at the remote Arctic research stations Gruvebadet (67 m a.s.l.) and Zeppelin (474 m a.s.l.), Ny-Ålesund, during May 2018. The aim of this study was to improve our understanding of processes governing secondary aerosol formation in remote Arctic marine environments. We run the Lagrangian chemistry transpor
In recent years, FLASH irradiation has attracted significant interest in radiation research. Studies have shown that irradiation at ultra-high dose rates (FLASH) reduces the severity of toxicities in normal tissues compared to irradiation at conventional dose rates (CONV), as currently used in clinical practice. Most pre-clinical work is currently carried out using charged particle beams and the b
Purpose – The road freight industry is becoming more and more complex. An increasing number of actors participating in the transport process has been highlighted. Simultaneously, transport constellations become more fragmented. With transport as feature of the product-offer, sending companies face new challenges. While transport has as part of the product offer influence on the customer satisfacti
Analysing the environmental impact connected to biofuels has lately become more important due to the European Commission’s energy and climate target for 2020. These targets includes among others, 20 % reduction of greenhouse emissions and 20 % energy efficiency. One important solution for achieving this climate target is to increase the renewable fuel sector. In order to decide which biofuels that
Med ett politiskt parti anklagat för fascism i riksdagen, och nynazister marscherande på gatorna är frågor om demokrati och frihet viktigare än någonsin. Var bör yttrandefrihetens gränser dras? Bör den överhuvudtaget begränsas? Syftet med den här uppsatsen är att utforska en möjlig lösning till de problem som dagens demokrati står inför. Det här åstadkoms genom en konstruktion av ett konceptuellt With a political party accused of fascism in the Swedish parliament and neo-nazis marching in the streets, questions of democracy and freedom of expression are as important as ever. Where to draw the boundaries of the freedom of expression? Why have, or limit, such freedoms in the first place? The purpose of this thesis is to investigate a possible solution to the problems facing contemporary demo
Abstract Author: Ella-Kari Meyrell Title: Strategy for welfare - a discourse analytical study of culture in health, social care and school organizations Supervisor: Håkan Jönson Assessor: Torbjörn Hjort The aim of this study was to examine how culture (as “the arts”) is constructed as a strategy in welfare work. The empirical material was based upon 160 articles from Swedish printed and web base
Within the Renewable Energy Directive, the European Union has embedded sustainability criteria, addressing sustainable biofuels. Due to criticism, the sustainability criteria have been re-examined by the EU in the light of Indirect Land Use Change (ILUC). This thesis focuses on the sustainability understanding of the EU on biofuels, through assessing the sustainability criteria in the realms of su
Background: Intensive rehabilitation is one of the most important aspects of care for people with stroke, and there is evidence that it leads to better recovery and higher levels of independence. However, pressure on resources in government funded secondary and primary healthcare settings means that for many people with stroke, intense rehabilitation is not available. Effective and efficient ways
Coastal areas around the world are being shaped by many natural phenomena, as well as by man-induced activities. Hydrodynamic phenomena such as wind-generated waves, extreme storms and seasonal tides cause a continued change in topography and the natural sediment formation in the nearshore zone as a result of erosion and accumulation. Therefore, the nature of the nearshore zone and its protection
Strålbehandling kan användas för att behandla olika cancerdiagnoser. Man vill då kunna rikta strålningen mot tumören medan så lite frisk vävnad som möjligt bestrålas. Olika studier visar att för patienter som behandlas med strålbehandling för cancer i vänster bröst är förekomsten av och dödligheten i olika hjärtsjukdomar högre än för de som behandlas med strålbehandling för cancer i höger bröst. DPurpose: To evaluate the benefits of using respiratory gating for left-sided breast cancer in the form of dose-sparing and biological effects to the heart and to investigate the set-up deviations for patients treated with respiratory gating in order to find an optimal correction strategy for this group of patients. Materials and methods: Nineteen patients treated with respiratory gating for left-
Det har aldrig gjorts något samlat försök att systematisera sakrätten från lagstiftarens sida. Särskilt separationsrättsliga problem är beständiga över tiden. Uppfattningarna om rättsläget beträffande separationsrätt vid sammanblandad egendom går isär. Det är svårt att se tydliga mönster i rättstillämpningen och förutsägbarheten är begränsad. Generellt sätt är rättsläget oklart. Vi vet inte vilka Rights in rem have never been systematized by the Swedish legislator. Especially problems regarding separation rights are recurring. Views differ on the owner’s right to separate intermixed property in a debtor’s bankruptcy or execution. The legal position is uncertain and predictability is limited. Since there is no general principle of separation right in the event of intermixed property and cas
This is the report of a master thesis in Mechanical engineering with industrial design at Lund University Faculty of Engineering, in collaboration with Ikea Components AB (ICOMP) in Älmhult. Furniture dampers are a desired feature by most customers and are practically a standard in kitchen drawers and cabinet fronts. IKEA’s vision is that this feature will spread to involve the entire househo
