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Production of Ectoines and Poly(3-Hydroxybutyrate): High Cell-Density Cultivation of Halomonas Boliviensis
This thesis reports a study involving the use of Halomonas boliviensis, a moderate halophile, for production of biopolyester poly(3-hydroxybutyrate) (PHB) and compatible solutes ectoine and hydroxyectoine through high cell-density cultivation comprising fed-batch cultures. PHB is a biodegradable plastic produced by bacteria as energy reserve and can potentially be used as a replacement of fossil b
Krishantering, hushåll och stormen Gudrun : Att analysera hushålls krishanteringsförmåga och sårbarheter
Popular AbstractStörre kriser och katastrofer som stormen Gudrun och dess konsekvenser är sannolikt att vänta i framtiden. Det råder dock ovisshet om vilka kriserna kommer att vara och under vilka förutsättningar. Nya och kompletterande vetenskapliga studier och metoder inom kris- och katastrofforskningen måste till för att öka samhällets kunskap om och förmåga att hantera kända och okända hotbildSevere crises and disasters such as the Hurricane Gudrun and their consequences will probably occur in the future. However, there are many uncertainties concerning disasters and their effects. New scientific approaches and methods for crisis and disaster research must be developed to increase the knowledge and ability of societies to manage known and unknown threats. Substantial research on the em
Insulation of traditional Indian clothing: Estimation of climate change impact on productivity from PHS (predicted heat strain) model
Major databases on western clothing and their thermal properties are available, but information on non-western clothing is lacking. A recent ASHRAE project 1504 TRP, Extension of the Clothing Insulation Database for Standard 55 and ISO 7730 dealt with the issue. Simultaneously, a co-operation study at Indian workplaces allowed us to acquire some sets of the traditional clothes used at construction
Hereditary hypertrophic cardiomyopathy in children and young adults—The value of reevaluating and expanding gene panel analyses
Introduction: Sudden cardiac death (SCD) and early onset cardiomyopathy (CM) in the young will always lead to suspicion of an underlying genetic disorder. Incited by the rapid advances in genetic testing for disease we have revisited families, which previously tested “gene-negative” for familial predominantly pediatric CM, in hopes of finding a causative gene variant. Methods: 10 different familie
Comparative analysis of detailed and reduced kinetic models for CH 4 + H 2 combustion
Directed relation graph with error propagation (DRGEP) method combined with extensive validation for 0D, 1D and 2D CFD modeling supported by sensitivity and Rate-Of-Production (ROP) analyses are implemented for comparative study of detailed and reduced kinetic mechanisms for CH 4 + H 2 combustion. To this end, two detailed kinetic mechanisms, namely AramcoMech 2.0 and recently updated Konnov me
Deep learning for segmentation of 49 selected bones in CT scans : First step in automated PET/CT-based 3D quantification of skeletal metastases
Purpose: The aim of this study was to develop a deep learning-based method for segmentation of bones in CT scans and test its accuracy compared to manual delineation, as a first step in the creation of an automated PET/CT-based method for quantifying skeletal tumour burden. Methods: Convolutional neural networks (CNNs) were trained to segment 49 bones using manual segmentations from 100 CT scans.
Influential Moments in City Planning Meetings : A Study of Decision-Making Situations in a Jordanian Municipality
The shaping of a city and its future relates to official decisions made in city planning meetings, where daily planning matters and decision-making processes adapt to changing societal circumstances. The interest of this research lies in how planning is officially established, managed and practiced in the setting of a Jordanian city, and its local districts. This interest leads the research to obs
Global analysis of continental boundary layer new particle formation based on long-term measurements
Atmospheric new particle formation (NPF) is an important phenomenon in terms of global particle number concentrations. Here we investigated the frequency of NPF, formation rates of 10 nm particles, and growth rates in the size range of 10–25 nm using at least 1 year of aerosol number size-distribution observations at 36 different locations around the world. The majo
Sustainable Thermal and Acoustic Retrofitting of Façade Walls
Faced with an acute problem of housing options during the 1960s, the Swedish government introduced a nationwide campaign of ‘A Million New Homes’. In order to achieve the aim of the campaign, the construction of these homes depends on cheap and fast building methods which do not result in the homes being energy efficient nor are they equipped with good acoustical properties. As time progress and s
Developing a programmable mRNA pseudouridylation system to monitor gene-specific translation in human cells
A guide in the darkness; A system shedding light on mRNA pseudouridylation by PUS7 Proteins, the building blocks of life, are produced from messenger RNA (mRNA). mRNA is built by four ribonucleotides, namely adenine (A), guanine (G), cytosine (C) and uridine (U). Interestingly, RNA includes also chemically modified versions of the above nucleotides affecting many physiological processes. The most
Spray-dried powders for inhalation
The pulmonary route has emerged as a promising strategy for delivering protein therapeutics, particularly for patients suffering from respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and pulmonary infections. This project investigated the effect of operating parameters of a laboratory spray dryer on the characteristics of powders composed of Bovine Serum Albumin
Stadsplaneringens betydelse för segregation i svenska städer - en kartläggning av kommunernas arbete mot segregation
Segregation är ett föränderligt tillstånd som är komplext och påverkar såväl enskilda individer som samhället i stort. Exempelvis är stadsplaneringen en bakomliggande orsak som kan påverkar segregationen i en stad. För att det verkligen ska kunna ske en förbättring är det emellertid av stor vikt att åtgärder vidtas på olika plan och av olika aktörer. Det ursprungliga syftet bakom arbete är att utSegregation is a changing condition that is complex and affects individuals but also the society. Urban planning is for example an underlying cause that can affect segregation in a city. However, in order for an improvement, it is of great importance that measures are taken at different levels and by different actors. The primary purpose of the report was to study the impact that urban planning h
Barnets bästa eller domstolens handlingsmakt? Om bedömningen av barnets bästa i vårdnadstvister
Principen om barnets bästa ska vara avgörande i alla frågor som rör vårdnad, boende och umgänge. Den bärande principen återfinns i både FN:s barnkonvention och i föräldrabalken. Principen ska fungera som en rättslig vägledning vid alla utredningar i mål som rör barn, men det finns ingen universellt fastslagen definition av vad som faktiskt är barnets bästa. Utgångspunkterna är att bedöma barnets b
Universell jurisdiktion i Sverige - Om regelsystemet som möjliggör och begränsar utövning av universell jurisdiktion i svensk rätt
Universalitetsprincipen utgör en jurisdiktionsgrund enligt svensk rätt. I slutet av år 2022 meddelade Högsta domstolen ett prejudicerande beslut som behandlade hur universell jurisdiktion ska förstås enligt svensk rätt. Högsta domstolen fastslog i detta fall bland annat att den misstänkte måste ha en tillräcklig anknytning till Sverige för att det ska finnas ett svenskt rättskipningsintresse vid uThe principle of universality constitutes a basis for jurisdiction under Swedish law. At the end of 2022, the Supreme Court delivered a precedent- setting decision dealing with how universal jurisdiction should be interpreted according to Swedish law. The Supreme Court determined that for Swedish courts to exercise universal jurisdiction, there has to be a Swedish judicial interest, which is decid
Partial denitrification as nitrite provider for mainstream anammox
Anammox-processen erbjuder en hållbar och energieffektiv metod för biologisk kväve-avskiljning inom avloppsrening. Men bakterierna som utför arbetet kväver en källa till nitrit, och en möjlig lösning på detta är att kombinera metoden med partiell denitrifikation. Kan ett samarbete mellan dessa olika grupper av mikroorganismer upprättas, och vilken påverkan har typen av kolkälla som används i proceIn traditional wastewater treatment, nitrogen is removed through the biological process combination of nitrification and denitrification. Although it is a well-established method, the need for aeration and possible addition of an external carbon source results in it being an energy-negative and costly process, thus making alternative methods for nitrogen removal compelling to examine. Anaerobic am
Film formation of mixed-halide perovskites for PSCs
Perovskitsolceller har blivit ett populärt forskningsområde eftersom de har haft en exceptionellt snabb utveckling i verkningsgrad under de senaste åren. Trots att perovskitbaserade solceller nu har nått verkningsgrader jämförbara med kiselsolceller, så återstår flera utmaningar för att möta solcellsmarknadens förväntningar för de applikationer där man hoppas att perovskiterna ska komplettera kiseOver the last few years there has been a steady increase in interest in the exploration of perovskite materials within photovoltaic research. This can to a large extent be attributed to the incredible pace at which solar cells based on perovskites have improved in efficiency during the same time period. Perovskite solar cells (SCs) are not only an alternative to today’s market leading silicon base
Hur aktsam kan en sexköpare förväntas vara? - Om innebörden av aktsamhetskravet i 6 kap. 13 § BrB när sexköp av barn i 6 kap. 9 § BrB bedöms och dess förenlighet med effektivitets- och rättssäkerhetshänsyn
Från och med den 1 januari 2020 skärptes straffskalan för sexköp av barn. Syftet med åtgärden var att förstärka det straffrättsliga skyddet för ungdomar mot att dras in i prostitution. Brottet är förknippat med låg åtalsfrekvens. Det har tidigare förklarats med att aktsamhetskravet i förhållande till ålder i 6 kap. 13 § BrB - som täcker flera sexualbrott med åldersgräns - var särskilt svårt att upIn January 2020 the range of punishment for exploitation of a child through the purchase of a sexual act got stricter. The reasoning behind the change was to strengthen the criminal justice protection for these children. Exploitation of a child through the purchase of a sexual act is associated with a low prosecution frequency. An explanation for this has been that the rule of negligence in the si
Dynamics of GABA Receptor composition in the recovery phase of stroke – Effect of anti-inflammatory treatment with AMD3100
GABAergic Neurotrasmission – A “cross-talker” between inflammation and neural plasticity in stroke Stroke is a leading cause of disability and no pharmacological treatment is currently available to promote recovery in suffering patients. A major part of research is focusing on finding new biological targets which can be pharmacologically intervened with, providing favorable results in facilitatin
Vidareutveckling av katalysatorer för pre-reforming i bränslecellssystem
Heterogena katalysatorer för användning i bränslecellssystem har undersökts baserat på aktiv fas och tillverkningsmetoder för granulat- och monolitkatalysatorer. Katalysatorerna tillverkades genom att använda θ – aluminiumoxid som bärare, dopad med lantan och cerium, där den aktiva fasen bestod av ädelmetall X och nickel i varierande halter. Analys gjordes genom att låta en blandning av vattenångaHeterogeneous catalysts to be used in a pre-reformer for fuel cell systems have been investigated based on active phase composition and catalyst preparation methods for granulate and monolithic catalysts. The catalysts were manufactured using θ – aluminum oxide as carrier, promoted with lanthanum and cerium, with active phases consisting of noble metal X and nickel in various concentrations. Analy
