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Background: The Tau PET ligand 18F-AV1451 has been shown to reliably detect paired helical filaments of tau in Alzheimer's disease, but it is not yet known whether it binds to the tau aggregates present in patients with mutations in the gene (MAPT) coding for the tau protein. Further, no study has yet compared the cerebral retention of 18F -AV1451 with the tau aggregates revealed using neuropathol
Background. In the European Study for Pediatric Ph+ ALL (EsPhALL), a total of 128 patients aged 1 to 18 years diagnosed with ALL and evidence of t(9;22)(q34;q11) received post-Induction Imatinib on top of BFM high risk chemotherapy backbone, either in Good Risk (GR) (after randomization, n=58) or in Poor Risk (PR) (n=70), as defined according to early response to the National induction treatment.
Softwood bark contains a large amounts of extractives—i.e., soluble lipophilic (such as resin acids) and hydrophilic components (phenolic compounds, stilbenes). The effects of the partial removal of water-soluble extractives before acid-catalyzed steam pretreatment on enzymatic digestibility were assessed for two softwood barks—Norway spruce and Scots pine. A simple hot water extraction step remov
Speed and accuracy are crucial prerequisites in the application of proteomic methods to clinical medicine. We describe a microfluidic-based nanovial array for rapid proteolytic processing linked to MALDI-TOF MS. This microscale format consumes only minute amounts of sample, and it is compatible with rapid bioanalytical protocols and high-sensitivity readouts. Arrays of vials (300 mu m in diameter
In the bioconversion of lignocellulosic materials to ethanol, the cost of the raw material and the cost of the enzymes have been identified as the major costs for the product. In addition, many lignocellulosic materials contain considerable amounts of five-carbon sugars which are not easily fermented to ethanol. The possibility of improving the cost-intensive steps was investigated. The steam pre
In recent decades, information technology has enjoyed an ever-increasing degree of influence upon society. The use of technology has proliferated, bleeding into all human activities, and now extends into the most private activities of individuals. Unfortunately the perpetrators of serious crimes have not missed the revolution. Technology has marked off many working terrains including that of serio
The concentrations of cartilage proteoglycan (aggrecan), stromelysin-1, tissue inhibitor of metalloproteinases-1 (TIMP-1) and procollagen II C-propeptide in knee joint fluid and the levels of aggrecan, hyaluronan and keratan sulfate in serum were measured before and after exercise in 33 healthy athletes. The samples before exercise were obtained after 24 h rest from running or soccer and the sampl
Populärvetenskaplig sammanfattning: Kartläggning av långbensgroda på Öland Amfibier världen över har minskat kraftigt sedan1970-talet. Orsakerna är många men flera är okända. Fem av tretton amfibier i Sverige är hotade och åtgärder genomförs för att öka arters populationer. Biogeografisk uppföljning är ett nationellt program för uppföljning av amfibier som kan upptäcka förändringar i en arts popAs a result of e.g. habitat loss and diseases, a global decline of amphibians is a fact. In order to prevent further declines and to improve the conservation status for amphibians in Europe, the member states have to report the status for amphibians every sixth year to EU. In Sweden, the County Administrative Board in Scania is responsible for coordinating the biogeographic monitoring of amphibian
Thirty right-handed participants were presented with emotional pictures either to the left or to the right visual field. The pictures were shown for a duration of 150 ms to make sure that they were exclusively presented to one hemisphere only. Eye movements were recorded with electroocularogram for each participant throughout the test. A total of 30 pictures were chosen on the basis of their valen
Två grundläggande rättsgrundsatser inom civilprocessrätten är principen om jura novit curia och kontradiktionsprincipen. Jura novit curia innebär att domstolen känner lagen och att domstolen ska tillämpa den adekvata rättsregeln på tvisten, oavsett om parterna baserat sin talan på denna eller ej. Kontradiktionsprincipen, som både finns i intern svensk rätt och i EKMR, stadgar att ingen får dömas oTwo fundamental principles in the Swedish procedural code are the principle iura novit curia and the principle of an adversarial procedure. Iura novit curia means that the court knows the law and that the judge is responsible for the application of the relevant legal rules, whether the parties have based their pleadings on these or not. The principle of an adversarial procedure, which exists both
Syftet med uppsatsen är att undersöka vilken roll allmänna intressen spelar i den svenska miljöprocessen. Vidare avser arbetet redogöra för de förutsättningar under vilka enskilda, organisationer och myndigheter kan företräda sådana intressen. Uppsatsen berör även vilka som beslutar i frågor som rör allmänna intressen. Då det finns en mängd allmänna intressen som kan aktualiseras i svensk rätt harThe aim of this essay is to investigate the role of public interests in Swedish environmental law. Furthermore the essay aims to explain under which circumstances individuals, organizations and government agencies may represent public interests. The essay also discusses the question of who rules in matters concerning public interests. Since a variety of different public interests may occur in Swed
Rapporten är ett examinerande moment i kursen Brandteknisk riskvärdering. Syftet med rapporten är att utvärdera personsäkerheten vid brand för besökarna på Halmstadtravet och ge förslag på eventuella förbättringar. Syftet är även att studenterna ska tränas i sin ingenjörsmässiga förmåga. I byggnaden som utvärderas finns bland annat restaurang, kök, sittplatsläktare och caféverksamhet. Det redogörThe report is an examination element of the course Brandteknisk riskvärdering. The purpose of the report is to evaluate human safety of visitors in case of fire at the racetrack Halmstadtravet and suggest possible solutions if the human safety is deemed insufficient. The purpose is also to train the students in their engineering capability. The method is to choose several fire scenarios that chal
Varg (Canis lupus) i södra Sverige Efter att ha varit nästan utrotad från landet 1965 så har vargen nu stadigt återhämtat sig och ökar mer och mer i antal, dock finns den svenska varg populationen främst i mellersta Sverige. Men i samband med att populationen ökar så flyttar fler och fler djur söderut. Etableringen av rovdjur så som varg har visat sig ha stor positiv påverkan på ekosystem men ä
En fjärdedel av de homosexuella, bisexuella och transpersoner som deltagit i en stor undersökning år 2013 hade blivit utsatta för hot och våld. Personerna utsätts bland annat för att de inte tillhör normen. Enligt straffskärpningsregeln i 29 kap. 2 § 7 p. BrB är det en försvårande omständighet vid bedömningen av straffvärdet om ett motiv för en brottslig gärning varit att kränka en person, folkgA quarter of the lesbian, gay, bisexual and transgender persons participating in a survey in 2013 had been exposed to threat and violence. One of the reasons for them being targeted was that they do not conform to the norm. According to the penalty enhancement provision in Chapter 29, Section 2, Subsection 7 of the Swedish Penal Code if a motive for a crime is to aggrieve a person, ethnic group o
Införandet av ombud för barn i vårdnadstvister har varit omdiskuterat under en mycket lång tid. Frågan har diskuterats av sakkunniga, behandlats i flera utredningar samt varit föremål för flertalet riksdagsmotioner. Än har frågan inte resulterat i någon ny lagstiftning. Uppsatsens syfte är att, ur ett barnrättsperspektiv, utreda om ett införande av ombud för barn i vårdnadstvister kan stärka barThe question of whether a legal representative for children in custody disputes should be introduced in Swedish legislation has been discussed for a long time. Despite this, the discussions have not yet resulted in any legislation. The purpose of this essay is to, from a children’s rights perspective, investigate whether the legislation of representatives of children in custody disputes could st
I svensk straffprocessrätt har omedelbarhetsprincipen haft stor betydelse sedan rättegångsbalken infördes år 1948. Den innebär att domstolen bara ska döma över det som har framkommit under huvudförhandlingen. Domstolen har inte innan huvudförhandlingen läst polisens utredning, utan parter och vittnen ska komma till domstolen och lämna sin berättelse direkt inför rätten. Den 1 januari 2022 infördeIn Swedish criminal procedure law, the principle of immediateness has been of great significance since the code of judicial procedure came into effect in 1948. This implies that the court should only judge and present verdicts based on what has appeared during the main hearing. Hence, the court will not have read the pre-trial investigation before the main hearing. Instead, the implicated parties
Lojalitetsplikten i kommersiella avtalsförhållanden kan definieras som skyl-digheten för parterna i relationen att tillvarata motpartens intressen utöver sina egna. Lojalitetsplikten kan härledas långt tillbaka i historien men det är först under 1900-talets andra hälft som saker började hända och denna utveckling tog rejäl fart under de senaste ca 20 åren. Lojal samverkan mellan parterna står iblaThe principle of loyalty in commercial relations can be defined as an obliga-tion for the parties to safeguard the other party’s interests in addition to their own. The principle of loyalty can be derived far back in history, but it was only during the second half of the 20th century that things started to happen, and this progress took off in the last 20 or so years. Loyal collaboration be-tween
Uppsatsens övergripande syfte är att utreda såväl innebörden som omfattningen av Migrationsverkets och migrationsdomstolarnas utredningsansvar i asylärenden/ mål enligt 23 § FL respektive 8 § FPL. För att kunna ge en tillfredsställande bild av utredningsansvaret studeras dessutom, om än mer kortfattat, bevisreglerna i asylärenden/mål. Uppsatsen ger inledningsvis en introduktion till regleringen The overall purpose of the thesis is to investigate the meaning and scope of the Swedish Migration Agency's and the Migration Courts' investigative responsibility in asylum cases /cases according to § 23 FL and § 8 FPL. In order to be able to give a satisfying picture of the investigative responsibility, the rules of evidence in asylum cases /cases are also studied, but more briefly. The
The overall purpose of this thesis is to investigate the feasibility of producing electrofuels from CO2 and H2 in connection to a CHP plant equipped with carbon capture technology. This is done by investigating the production of e-methane, e-methanol and e-kerosene from captured CO2 and H2 produced from electrolysis. Each of the processes is designed and analyzed in Aspen HYSYS. From this, the ene
AimA significant number of children living in Sweden are bilingual, but how language screening is performed in this group is unknown. We investigated child healthcare nurses' perceptions of the language screening of bilingual children aged 30-36months, together with their clinical practices. MethodsAn online questionnaire was completed by 863 nurses who performed language screening of bilingual ch
