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OBJECTIVES: To estimate the total direct medical costs to society for patients with type 2 diabetes in Sweden and to investigate how different factors, for example diabetic late complications, affect costs. DESIGN: Cross-sectional data regarding health care utilization, clinical characteristics and quality of life, were collected at a single time-point. Data on resource use cover the 6-month perio

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Popular Abstract in Swedish Syftet med denna avhandling är att utforska fenomenet vetenskapligt kritiskt tänkande, när det gäller dess olika innebörder, villkor och utveckling. Kritiskt tänkande studeras genom att analysera olika filosofiska och pedagogiska texter, utifrån ett hermeneutiskt-fenomenologiskt perspektiv. Avhandlingen som är skriven på engelska erbjuder läsaren en inblick i hur min egThe purpose of this thesis is to explore the phenomenon of critical thinking in scholarship as regards its meanings, conditions, and development using a hermeneutic-phenomenological approach. This exploration takes its departure in ancient Greece, following a historical movement of the phenomenon up to present day perspectives on critical thinking, revealing a range of different meanings and condi

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Popular Abstract in Swedish Tumörer uppstår då celler i kroppen plötsligt börjar växa och dela sig obehindrat. Tumöromvandlingen är ett resultat av mutationer i cellens gener som kontrollerar hur celler tillväxer och differentieras. Sådana gener kallas för onkgener och suppressorgener. Tumörer som respekterar sin omgivning kallas för benigna men så snart de börjar växa invasivt in i omkringliggandNatural killer (NK) cells and T lymphocytes are the major effector cells that can recognize and kill tumor cells. NK cells have a constitutive cytotoxic activity and kill a wide spectrum of tumor cells while T cells recognize specific tumor antigens and need to be activated through their TCR to differentiate into cytotoxic T lymphocyte (CTL) killers or T helper cells. Interleukin-2 is the principa

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Ab initio calculations of low-lying electronic states of CrH are presented, including potential energies, dipole and transition dipole moment (TDM) functions, and radiative lifetimes for X (6)Sigma(+), A (6)Sigma(+), 3 (6)Sigma(+), 1 (6)Pi, 2 (6)Pi, 3 (6)Pi, and (6)Delta. Calculation of dynamic correlation effects was performed using the multistate complete active space second-order perturbation m

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BACKGROUND: Traditionally oocytes have been exposed to sperm overnight, for 16-20 h. This long period of co-incubation, however, has been shown to create problems with high levels of reactive oxygen species (ROS), which may affect embryo viability and cause hardening of the zona pellucida. Recently, a positive effect of reducing the co-incubation time to 90-120 min was reported. The objective of t

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In order to assess the non-evaporative components of the reduced thermal insulation of wet clothing, experiments were performed with a manikin and with human subjects in which two layers of underwear separated by an impermeable barrier were worn under an impermeable overgarment at 20 °C, 80% RH and 0.5 ms-1 air velocity. By comparing manikin measurements with dry and wetted mid underwear layer, th

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This study reports carbon and water fluxes between the land surface and atmosphere in eleven different ecosystems types in Sub-Saharan Africa, as measured using eddy covariance (EC) technology in the first two years of the CarboAfrica network operation. The ecosystems for which data were available ranged in mean annual rainfall from 320 mm (Sudan) to 1150 mm (Republic of Congo) and include a spect

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Hollow fibre (HF) membrane modules were applied in continuous mode for equilibrium sampling through membranes (ESTM) of polar organic pollutants. Phenolic compounds (chlorophenols, cresols and phenol) served as model substances and ESTM was tuned towards the measurement of freely dissolved concentrations (C(free)). HF membrane modules were constructed using thin-walled membrane, 1-m module length

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After identifying an association between maternal Epstein-Barr virus (EBV) reactivation and acute lymphoblastic leukemia (ALL), the authors analyzed a nested case-control study within Finnish and Icelandic maternity cohorts with 7 million years of follow-up to confirm EBV's role in ALL. Offspring of 550,000 mothers were followed up to age 15 years during 1975-1997 by national cancer registries to

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Objective: The aim was to evaluate the outcome of fertility-sparing treatment in ovarian borderline tumors and early invasive ovarian cancer. Materials and methods: All women diagnosed with an ovarian borderline tumor or early invasive ovarian cancer who were treated with fertility-sparing surgery at the University Hospital in Lund between 1988 and 2002 were identified and included in the study (n

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Paper A investigates how to simulate a differentiated mean in cases where interchanging differentiation and expectation is not allowed. Three approaches are available, finite differences (FD's), infinitesimal perturbation analysis (IPA) and the likelihood ratio score function (LRSF) method. We study FD's under discontinuities and show that the optimal decay rate of the mean square error is typical

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Accurate measurements of solute concentration are needed to conduct studies of solute transport process in unsaturated soil. In this paper we present a method of obtaining accurate measurements in and space using dye infiltration and image analysis. The soil color was related to the dye concentration in the soil (C-s) using 74 small calibration samples. The overall root mean square error (RMSE) 0.

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Background: Obesity, type 2 diabetes and atrial fibrillation (AF) are closely associated, but the underlying mechanisms are not fully understood. We aimed to explore associations between body mass index (BMI) or weight change with risk of AF in patients with type 2 diabetes. Methods: A total of 7,169 participations with newly diagnosed type 2 diabetes were stratified according to baseline BMI, and

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Our main purpose with this study is to examine and elucidate the recovery process that occurs when women choose to break up from destructive relationships. Our aim is also to clarify what, by the women themselves, is considered to be efficient help in relation to what in fact is offered in actuality. The idea of this selection was that we, in the study of the recovery process, would make a compili

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This master thesis was conducted at Volvo Car Corporation, VCC, in Gothenburg within the Manufacturing Engineering department. It is based on the P11-project (the new model S40) where the process verification has been examined and analyzed. The purpose of the thesis is to investigate the reasons behind remaining and new problems at late stages in the development process, as well as possibilities f

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Sydvästra Grönlands arkeiska berggrund (North Atlantic Craton, NAC) intruderades av ett stort antal mafiska intrusioner och diabasgångar under arkeikum och proterozoikum, vars åldrar är dåligt kända. Detta arbete omfattar dateringar av fem intrusioner med U-Pb metoden av mineralen zirkon och baddeleyit från tre olika generationer av mafiska bergarter. En mafisk-ultramafisk lagrad intrusion i FiskeThe Archaean bedrock of southern Greenland (the North Atlantic Craton) is host to a large number of mafic intrusions and dyke swarms. This study present a robust U-Pb zircon age of 2990.1 ± 13 Ma for a mafic-ultramafic layered intrusion in the Fiskefjord region and four baddeleyite U-Pb ages of doleritic dykes that range between c. 2500 and c. 2050-2030 Ma. The dyke located SE of Ameralik Fjord is

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Background: Lung densitometry is an effective method to assess overall progression of emphysema, but generally the location of the progression is not estimated. We hypothesized that progression of emphysema is the result of extension from affected areas toward less affected areas in the lung. To test this hypothesis, a method was developed to assess emphysema severity at different levels in the lu

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We present detailed observations of the bright short-hard gamma-ray burst GRB 090510 made with the Gammaray Burst Monitor (GBM) and Large Area Telescope (LAT) on board the Fermi observatory. GRB 090510 is the first burst detected by the LAT that shows strong evidence for a deviation from a Band spectral fitting function during the prompt emission phase. The time-integrated spectrum is fit by the s