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Background: Risky sexual behavior (RSB) is one of the major youth sexual and reproductive health problems globally, including in Ethiopia. RSB among youth increases the risk of HIV infection, other sexually transmitted infections (STIs), unintended pregnancy, and unsafe abortion. Therefore, the aim of this study was to examine RSB and its associated factors among university students in Ethiopia. M

BACKGROUND: Obesity, assessed by body mass index (BMI), is an established risk factor for 13 cancers. We aimed to identify further potential obesity-related cancers and to quantify their association with BMI relative to that of established obesity-related cancers.METHODS: Using Cox regression models on 4,142,349 individuals in Sweden (mean age 27.1 years at weight measurement), we calculated hazar

BACKGROUND: Beneficial effects from practising a Paleolithic diet as compared to a diabetes diet on weight, waist circumference, satiety, leptin, HbA1c and glucose control in randomised controlled trial participants with type 2 diabetes could be due to lower leptin resistance. Support for this hypothesis comes from an in vitro experiment that showed that digested wheat gluten, which is excluded fr

BackgroundIt remains unclear as to why some individuals at low risk of cardiovascular disease (CVD) develop severe coronary atherosclerosis, while those at high CVD risk may remain free from coronary atherosclerosis.PurposeUsing Coronary Computed Tomography Angiography (CCTA), we aimed to identify factors associated with absence and severe coronary atherosclerosis in subjects from the general popu

BACKGROUND: Prior research has established a positive association between the single-measured triglyceride-glucose (TyG) index and hypertension. Nevertheless, longitudinal studies addressing the enduring impact of TyG index on incident hypertension are lacking. This study sought to explore the association between cumulative TyG index (cum-TyG) and incident hypertension, especially obesity-related

Background: Human immunodeficiency virus type 1 (HIV-1) is one of the fastest-evolving human pathogens. Understanding HIV-1 transmission, within-host adaptation, and evolutionary dynamics is pivotal for development of interventions and vaccines. HIV-1 infection is generally caused by a single transmitted founder virus (TFV), and TFV sequences are typically obtained using single genome amplificatio

Streams of event weights in particle-level Monte Carlo event generators are a convenient and immensely CPU-efficient approach to express systematic uncertainties in phenomenology calculations, providing systematic variations on the nominal prediction within a single event sample. But the lack of a common standard for labelling these variation streams across different tools has proven to be a major

Background: Prostate cancer (PC) survivors may potentially use substances to cope with psychological distress or poorly controlled physical symptoms. Little is known, however, about the long-term risks of alcohol use disorder (AUD) or drug use disorders in men with PC. Methods: A national cohort study was conducted in Sweden of 180-189 men diagnosed with PC between 1998 and 2017 and 1 801 890 age-

BackgroundLoss to follow-up (LTFU) from tuberculosis (TB) treatment and care is a major public health problem as patients can be infectious and also may develop a multi-drug resistant TB (MDR-TB). The study aimed to assess whether LTFU differs by the distance TB patients travelled to receive care from the nearest health facility.MethodsA total of 402 patient cards of TB patients who received care

Objective: There is a lack of real-life studies on interleukin-17 (IL-17) inhibition in psoriatic arthritis (PsA). We assessed real-life 6- and 12-month effectiveness (i.e., retention, remission, low disease activity [LDA], and response rates) of the IL-17 inhibitor secukinumab in PsA patients overall and across 1) number of prior biologic/targeted synthetic disease-modifying antirheumatic drugs (

IntroductionAn important hallmark of cancer is escaping the immune system. Despite advances in immunotherapy, only a subset of patients experiences clinical benefits. It was shown that adoptive T cell or checkpoint inhibition therapy rely on the presence of conventional dendritic cells type 1 (cDC1). cDC1 excel in recruiting and priming protective CD8+ T cells through cross-presentation. However,

Purpose: Within the construction business pricing is traditionally done at current account. The purpose of this report is to investigate why pricing levels are low within the construction consultant industry in comparison to other consultant industries, as well as to examine what affects the choice of pricing models. In addition to this the report aims to analyze pricing models used today and to d

Oxytocin (OT) is a small neuropeptide, which is present in human plasma at extremely low endogenous levels of only a few pg/ml. It is mainly involved during labour and lactation but it has recently also been found that OT is involved in social behaviours like bonding and feeling empathy. During the last couple of years, the interest in OT has been raised and due to the matrix complexity, it is ver

The main goal of the project was to decrease the cooling time of a diamond anvil cell (DAC) by modifying an existing design. Modifications included change of materials, overall dimensions and a significant reduction of mass together with additional suggestions for decreased cool time. The initial design was known to function with current materials and dimensions. The first step of the thesis was

Denna studie behandlar barnpornografibrottets placering i Brottsbalken (BrB). Uppsatsens syfte är att utreda barnpornografibrottets placering i BrB och dess bakomliggande skäl. Placeringen av barnpornografibrottet granskas ur ett allmänkritiskt perspektiv, men även med ett barnperspektiv. Framställningen beskriver gällande rätt och brottets placering i ljuset av brottets skyddsintressen. Studien bThis thesis discusses the crime of child pornography and its placement in Swedish criminal law, “Brottsbalken” (BrB). The purpose of the thesis is to examine the placement of the crime in BrB and the reasons behind the placement. The placement of the crime is viewed with a general critical perspective, but also with a child perspective. The thesis describes how the law is designed and the placemen

In the prevailing retail climate sustainability has become an important factor of competition actualizing questions about why we buy green products, how we buy them and how they are marketed. These questions touches upon the contextualization of green products, they need to be made meaningful and functional to consumers. It is therefore interesting to study the processes involved in the production

Financial crises are recurring phenomena and studying how economic parameters affect outcome and recovery processes will most likely remain an area of intense research also in the years to come. The scope of this paper circulates around the causes and effects of two crises in the period 1985-2013 and their separate effects on the economies of Denmark, Sweden and Finland. Moreover, the main variabl

I dagens samhälle ställs allt högre krav på organisationer och dess förmåga att vara flexibla och anpassningsbara. Torts det slutar inte sällan förändringsarbeten i ett misslyckande. Forskningen kring kommunikation i organisationsförändringar har påvisat viktiga faktorer men är trots det fortfarande ett relativt outforskat område. Genom sju kvalitativa intervjuer och en netnografisk studie har vi In today's society there are increasing demands on organizations and its ability to be flexible and adaptable. However, many changes ends in failure. Research on communication in organizational changes has proven to be important factors, but is still a relatively unexplored area. Through seven qualitative interviews and a online ethnography, we have done a study that investigates employees exp

Automatiska förlängningar av avtal innebär att en ny bindningstid inträder om konsumenten inte senast vid viss tidpunkt säger upp avtalet. Att konsumentens passivitet är den omständighet som gör att den nya avtalstiden inträder, har bland annat gjort att sådana förlängningar jämförts med negativ avtalsbindning, vilket svensk rättsordning inte accepterar. Situationen är emellertid annorlunda när paAutomatic extension of contracts means that time-limited contracts are automatically extended unless the consumer terminates the contract a certain amount of time before it is to expire. The fact that the consumer’s inactivity is the reason why the contract is being extended has even led to a comparison between such automatic extensions and an illegal form of contracting called negative contract b