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Background: Progressive accumulation of α-synuclein is a key step in the pathological development of Parkinson's disease. Impaired protein degradation and increased levels of α-synuclein may trigger a pathological aggregation in vitro and in vivo. The chaperone-mediated autophagy (CMA) pathway is involved in the intracellular degradation processes of α-synuclein. Dysfunction of the CMA pathway imp
PURPOSE To improve the poor prognosis of patients with primary disseminated multifocal Ewing sarcomas (PDMES) with a dose-intense treatment concept. PATIENTS AND METHODS From 1999 to 2005, 281 patients with PDMES were enrolled onto the Euro-EWING 99 R3 study. Median age was 16.2 years (range, 0.4 to 49 years). Recommended treatment consisted of six cycles of vincristine, ifosfamide, doxorubicin, a
CONTEXT: The well-known side-effect profile of androgen-deprivation therapy (ADT) has significant quality-of-life (QoL) implications. Intermittent androgen deprivation (IAD) alternates androgen blockade with treatment cessation to allow hormonal recovery between treatment cycles, thus potentially improving tolerability and QoL. OBJECTIVE: To evaluate available evidence regarding the efficacy and t
One hundred and forty four current and 26 former workers in a plant producing barrels for rocket guns from an epoxy resin containing methyltetrahydrophthalic anhydride (MTHPA; time weighted average air concentration up to 150 uglm') were studied. They showed higher frequencies of work related symptoms from the eyes (31 v 0%; p < 0-001), nose (53 v 9%; p < 0-001), pharynx (26 v 6%; p < 0-01), and a
Micron-sized aluminum (Al) particles have recently been proposed as promising carbon-free energy carriers. To facilitate the application of micron-sized Al particles as fuel in practical energy generation system, this study experimentally investigates the underlying mechanisms of the ignition, stabilization and particle-particle collision in lifted Al particle cloud flames. High-resolution shadowg
Hematopoietic stem cells (HSC) are crucial to life. Daily and throughout the life span of an individual they are responsible for replacing approximately 10(12) mature blood cells. Mature cells are, for example, required for transportation of oxygen, defense against infections and to stop bleeding. Thus, our aim with this study was to characterize these rare murine (Lin-Sca1+c-kit+) and human (CD34
PII: 0006-8993(81)90498-4 Brain Research, 215 (1981) 147-161 © Elsevier/North-Holland Biomedical Press 147 B E H A V I O U R A L RECOVERY F O L L O W I N G T R A N S P L A N T A T I O N OF SUBSTANTIA N I G R A IN RATS SUBJECTED TO 6-OHDA LESIONS OF THE N I G R O S T R I A T A L PATHWAY. I. U N I L A T E R A L LESIONS STEPHEN B. DUNNETT, ANDERS BJORKLUND, ULF STENEVI and SUSAN D. IVERSEN Department
https://www.wnc.lu.se/sites/wnc.lu.se/files/dunnett_et_al_part_i_brain_res_1981.pdf - 2026-07-16
Transport in and through biological membranes that consist of lipid bilayers has a crucial role in many applications in the food or pharmaceutical industries. How to deliver an enzyme through the membranes without damaging the enzymatic activity or the "shelf-life" of the enzyme has been of large interest since 1970 [29-30]. In this work, we have shown that a thin lipid sponge phase (L3)
Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study Hye-Seung Lee1 Brant R. Burkhardt2 Wendy McLeod1 Susan Smith1 Chris Eberhard1 Kristian Lynch1 David Hadley1 Marian Rewers3 Olli Simell4 Jin-Xiong Sh
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/33%2006032016_679_33_Lee_DMRR_2013.pdf - 2026-07-16
Letters https://doi.org/10.1038/s41591-020-0930-4 1Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK. 2Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA. 3Department of Clinical Sciences, Lund University and Skåne University Hospital, Malmö, Sweden. 4Barbara Davis Center for Childhood Diabetes, Univers
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-04/120_MP68_Ferrat_Nature%20Med_2020.pdf - 2026-07-16
Information package for Marie Skłodowska-Curie fellows Version: 2, date of release: June 2024 EUROPEAN COMMISSION Directorate-General for Education, Youth, Sport and Culture Directorate C: Innovation, Digital Education and International Cooperation Unit C.2: Marie Skłodowska-Curie Actions European Research Executive Agency (REA) Directorate A: Marie Skłodowska-Curie Actions & Support to Experts Co
Microsoft Word - Free-riding in Group Work.doc Abstract — Studies have shown that group work offers great possibilities for deeper learning compared to some more traditional teaching formats [1], but it can also lead to some new problems such as free-riding. Different aspects of group psychology and behaviour as well as impropriate group sizes can be used to explain why and how free-riding develop
https://www.lth.se/fileadmin/lth/genombrottet/konferens2006/p_o_b_rjesson_mfl.pdf - 2026-06-09
From the management Survey The week after Easter, an organisational and social work environment survey will be sent out. At CEC we have decided to send the survey to you who are employed at CEC, but also to you who are a teacher in the CEC kollegium or a PhD student employed at another department. This as we regard you all to be important parts of our work environment. It is designed in a way that
https://www.cec.lu.se/staff-pages/staff-newsletters/25-march-2021 - 2026-07-15
The Gullviva project “GU LEDNING FÖR LIKA VILLKOR I VARJE AKTIVITET” Who are we? We are members of the “Action group” at the Science Faculty. • Johanna Stadmark, Geology • Tomas Brage, Physics • Ricardo Guillén, INES • Ragnhild Möller, Faculty office Plan for today • Presentation and introduction. • Introduction to GULLVIVA and systematic work for equal opportunities • Numbers – what can we
https://www.nateko.lu.se/sites/nateko.lu.se/files/2022-09/Geo%202022-09-22_final.pdf - 2026-07-16
The Mutual Reinforcement Between United Front Work and Cognitive Warfare: Implications for Countermeasures WEN-PING LIU LUND UNIVERSITY PSYCHOLOGICAL DEFENCE RESEARCH INSTITUTE | WORKING PAPER 2026:1 LUND UNIVERSITY PSYCHOLOGICAL DEFENCE RESEARCH INSTITUTE, WORKING PAPER 2026:1 1 The Mutual Reinforcement Between United Front Work and Cognitive Warfare: Implications for Countermeasures Dr. Wen-Ping
1 Heidelberg University LERU Doctoral Summer School in Heidelberg 2023 Concepts of intervention science applied to global challenges Equipping the next generation of scientists with understanding of main concepts and methods of intervention science and applying them to the converging global challenges: climate change, pandemics, and societal injustice “What starts out as science fiction today may
International Journal of Probiotics and Prebiotics Vol. 7, No. 3/4, pp. 135-144, 2012 ISSN 1555-1431 print, Copyright © 2012 by New Century Health Publishers, LLC www.newcenturyhealthpublishers.com All rights of reproduction in any form reserved ABSTRACT: The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to
https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_22_salami_ijpp_2012.pdf - 2026-07-16
1 LEARNING AGREEMENT FOR STUDIES The Student Last name (s) First name (s) Date of birth [DD-MM-YYYY] Nationality1 Sex [M/F/Other] Academic year 2019/2020 Study cycle2 Subject area, Code3 Phone E-mail The Sending Institution Name Lund University Faculty Social Sciences, International Office Erasmus code S LUND01 Department Address Box 117, 221 00 Lund, Sweden Country, Country code4 SE Contact perso
https://www.sam.lu.se/sites/sam.lu.se/files/learning_agreement_2019_lj_kf_mall.pdf - 2026-07-16
Senior lecturer Contact details Email: matthias [dot] lehner [at] iiiee [dot] lu [dot] se Phone: +46 46 222 02 07Organisation The International Institute for Industrial Environmental Economics Service point: 53 WebpageMatthias Lehners profile in Lund University research portalOther affiliations Affiliated researcher Centre for Retail and Logistics (REAL) Health and safety representative The Intern
https://www.iiiee.lu.se/matthias-lehner - 2026-07-16
The Journal of Clinical Investigation R e s e a r c h a r t i c l e 1jci.org Introduction Upon inflammation, an array of brain-mediated responses occurs. They are collectively referred to as the sickness syndrome and include fever, decreased food intake, inactivity, social withdrawal, and corticosteroid secretion (1, 2). These objective symptoms are accompanied by feelings of malaise and disco
