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BackgroundIn children, T-cell acute lymphoblastic leukemia (T-ALL) has inferior prognosis compared with B-cell precursor ALL. In order to improve survival, individualized treatment strategies and thus risk stratification algorithms are warranted, ideally already at the time of diagnosis. ProcedureWe analyzed the frequency and prognostic implication of mutations in NOTCH1 and FBXW7 in 79 cases of S
Abstract Background and aims. Microscopic colitis (MC), predominantly affecting women, is associated with thyroid disorders, although purely defined of which type, or compared with controls. Its association with subclinical thyroid disorders, and related increased risk of cardiovascular diseases, has never been examined. The aim was to examine the prevalence of autoantibodies and subclinical and c
1 ORPHEUS Labelling procedure Evaluators’ report of the PhD program at the Faculty of Medicine Lund University, Sweden ORPHEUS visiting committee : Prof. Andre NIEOULLON, Emeritus Professor , Aix-Marseille University, France, Chair of the committee Prof. John CREEMERS, KU Leuven, member of ORPHEUS Executive Committee, Belgium Prof. Nebojsa LALIC, Dean of the Faculty of Medicine, University of Belg
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Orientation Weeks 2020 SCHEDULE FOR INTERNATIONAL STUDENTS Sc he du le fo r i nt er na tio na l s tu de nt s 2 SCHEDULE FOR THE ORIENTATION WEEKS AUTUMN 2020 HEALTH AND SAFETY Great care has been taken to make sure that the events are in line with the regulations from the Swedish health authorities. The program is subject to change, and changes might be made with a very short notice. • All partici
BACKGROUND: Statins have been suggested to protect against breast cancer risk, but the observational evidence is inconclusive. We examined the association between statin use and breast cancer incidence among women at higher risk of breast cancer due to a history of benign breast disease (BBD).METHODS: Using Danish registries, we identified cancer-free women aged ≥50 years during 1996-2018 with a h
Rationale: Benzodiazepines, gabapentinoids, hypnotics, and opioids can depress respiration, alter sleep, and potentially affect outcomes in individuals treated with home mechanical ventilation (HMV) for obesity hypoventilation syndrome (OHS). Objectives: To analyze the association of benzodiazepines, gabapentinoids, hypnotics, and opioid use with hospitalization-free survival and mortality after s
Purpose: To present the outcomes of a randomised clinical trial for the treatment of progressive keratoconus using different kinds of riboflavin and the addition of sterile water in thin corneae. Methods: A randomised study using epithelium-off corneal cross-linking (CXL) with continuous UVA irradiance 9 mW/cm2 for 10 min (total fluence 5.4 J/cm2) and two kinds of riboflavin solutions: (i) isoosmo
Background: Despite robust evidence that genetic factors substantially influence both osteoporosis development and fracture risk, current screening guidelines fail to incorporate genetic factors into risk-assessment protocols. This study aims to determine personalized screening ages for osteoporosis based on polygenic risk score (PRS). Methods: This prospective cohort study utilized data from 223,
Tool wear intensity is one of the major performance and economic indicators of metal cutting processes. Understanding and control of tool wear and its governing mechanisms enables effective and sustainable manufacturing. Known wear mechanisms include abrasive, adhesive, chemical and diffusional, where their individual or combined action leads to an overall tool degradation. In this study, we prese
PURPOSE: To assess whether higher plasma 25-hydroxyvitamin D [25(OH)D] is associated with improved outcomes in colon cancer and whether circulating inflammatory cytokines mediate such association.EXPERIMENTAL DESIGN: Plasma samples were collected from 1,437 patients with stage III colon cancer enrolled in a phase III randomized clinical trial (CALGB/SWOG 80702) from 2010 to 2015, who were followed
BACKGROUND: Tofacitinib is a Janus kinase inhibitor for the treatment of ulcerative colitis (UC). Prospective real-world data are scarce.OBJECTIVES: To collect data on clinical outcomes, including health-related quality of life (HRQoL) and fatigue during treatment with tofacitinib.DESIGN: This is a prospective observational multicentre study in Sweden. In this analysis, outcomes at weeks 2, 8 and
Gastroenterology 2025;-:1–4 Early Dietary Fiber Intake Reduces Celiac Disease Risk in Genetically Prone Children: Insights From the TEDDY Study ietary fibers belong to a group of complex carbo- © 2025 The Author(s). Published by Elsevier Inc. on behalf of the AGA Institute. This is an open access article under the CC BY license (http:// creativecommons.org/licenses/by/4.0/). 0016-5085 https://doi.
Online seminar in Forensic Anthropology and Archaeology in Northern Europe (FAANE) (kopia 1) Online seminar in Forensic Anthropology and Archaeology in Northern Europe (FAANE) (kopia 1) Publicerad den 5 maj 2021 A novel seminar unites professionals across Northern Europe that engage in forensic anthropology, archaeology and legal medcine. The seminar is free to all and organized by the archaeology
https://www.forark.lu.se/article/online-seminar-in-forensic-anthropology-and-archaeology-in-northern-europe-faane-1/ - 2026-07-11
Introduction: The axonal myelin sheath is the main cause of magnetic resonance imaging (MRI) contrast between gray matter (GM) and white matter (WM) in the brain. It encloses a small pool of myelin water (MW) with a short T2 of about 15 ms. Common signal equations of MRI sequence assume an instantaneous RF excitation pulse followed by free relaxation. As known from ultra-short echo time (UTE) MRI,
Background Genetic determinants of stroke, the leading neurological cause of death and disability, are poorly understood and have seldom been explored in the general population. Our aim was to identify additional loci for stroke by doing a meta-analysis of genome-wide association studies. Methods For the discovery sample, we did a genome-wide analysis of common genetic variants associated with inc
Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease Full Terms & Conditions of access and use can be found at https://www.tandfonline.com/action/journalInformation?journalCode=kaup20 Autophagy ISSN: (Print) (Online) Journal homepage: https://www.tandfonline.com/loi/kaup20 Impact of differential and time-dependent autophagy activat
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_autophagy.pdf - 2026-07-15
Strengths and limitations of the neurosphere culture system The Neurosphere Culture System Various methods with slight variations in protocol exist for establishing and expanding neurosphere cultures. Generally, neurospheres are derived from a single-cell suspension of neural stem and progenitor cells isolated from the adult or fetal central nervous system (CNS), but neurosphere cultures can also
Final SIMM32 180326.iba SAKA003 GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Quantitative Methods: Multivariate Analysis For an always up-to-date online version, please visit the course site (check regularly for updates) SIMM32 Spring 2018, version 1.0 Welcome! SIMM32 Welcome to the Spring term’s course Quantitative Methods: Multivariate Analysis The aim of this course is for s
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/final_simm32_180326.pdf - 2026-07-15
Letters https://doi.org/10.1038/s41591-020-0930-4 1Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK. 2Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA. 3Department of Clinical Sciences, Lund University and Skåne University Hospital, Malmö, Sweden. 4Barbara Davis Center for Childhood Diabetes, Univers
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-04/120_MP68_Ferrat_Nature%20Med_2020.pdf - 2026-07-15
