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Infant Body Composition and Adipokine Concentrations in Relation to Maternal Gestational Weight Gain.

OBJECTIVETo investigate associations of maternal gestational weight gain and body composition and their impact on offspring body composition and adipocytokine, glucose, and insulin concentrations at age 4 months.RESEARCH DESIGN AND METHODSThis was a prospective study including 31 mother-infant pairs (N = 62). Maternal body composition was assessed using doubly labeled water. Infant body compositio

Polyelectrolyte-surfactant association-from fundamentals to applications

Mixed polymer-surfactant systems have broad applications, ranging from detergents, paints, pharmaceutical, and cosmetic to biotechnological. A review of the underlying polymer-surfactant association in bulk is given. While ionic surfactants bind broadly to polymers, nonionics only do so if the polymer has a lower polarity and can interact by hydrophobic interactions. Water-soluble polymers, which

Uniform and position-controlled InAs nanowires on 2('') Si substrates for transistor applications.

This study presents a novel approach for indirect integration of InAs nanowires on 2('') Si substrates. We have investigated and developed epitaxial growth of InAs nanowires on 2('') Si substrates via the introduction of a thin yet high-quality InAs epitaxial layer grown by metalorganic vapor phase epitaxy. We demonstrate well-aligned nanowire growth including precise position and diameter control

SNP in the genome-wide association study hotspot on chromosome 9p21 confers susceptibility to diabetic nephropathy in type 1 diabetes

Parental type 2 diabetes mellitus increases the risk of diabetic nephropathy in offspring with type 1 diabetes mellitus. Several single nucleotide polymorphisms (SNPs) that predispose to type 2 diabetes mellitus have recently been identified. It is, however, not known whether such SNPs also confer susceptibility to diabetic nephropathy in patients with type 1 diabetes mellitus. We genotyped nine S

Low preparedness before the loss of a wife to cancer and the widower's chronic pain 4-5 years later-a population-based study

ObjectiveThe focus of this study was on the impact of spousal loss on the development of chronic pain thereafter. More specifically, the aim was to investigate the effect of experiencing low preparedness before a wife's death and the widower's chronic pain 4-5 years after loss. MethodsIn a population-based study in the years 2004-2005, anonymous questionnaires were sent out to 907 men in Sweden wh

Source localization of rhythmic ictal EEG activity: A study of diagnostic accuracy following STARD criteria

PurposeAlthough precise identification of the seizure-onset zone is an essential element of presurgical evaluation, source localization of ictal electroencephalography (EEG) signals has received little attention. The aim of our study was to estimate the accuracy of source localization of rhythmic ictal EEG activity using a distributed source model. MethodsSource localization of rhythmic ictal scal

Flow of energy in the outer retina in darkness and in light

Structural features of neurons create challenges for effective production and distribution of essential metabolic energy. We investigated how metabolic energy is distributed between cellular compartments in photoreceptors. In avascular retinas, aerobic production of energy occurs only in mitochondria that are located centrally within the photoreceptor. Our findings indicate that metabolic energy f

Behaviour of nonsteroidal anti-inflammatory drugs and eight of their metabolites during wastewater treatment studied by hollow fibre liquid phase microextraction and liquid chromatography mass spectrometry.

In this work hollow fibre liquid phase microextraction combined with liquid chromatography mass spectrometry was applied for the determination of the nonsteroidal anti-inflammatory drugs (NSAIDs) ketoprofen, naproxen, diclofenac and ibuprofen as well as eight of their known human metabolites in wastewater samples. Extraction time and addition of tri-n-octylphosphine oxide (TOPO) to the liquid memb

Low androstenedione/sex hormone binding globulin ratio increases fracture risk in postmenopausal women. The Women's Health in the Lund Area study.

The Women's Health in the Lund Area (WHILA) project (n=6917) is a cohort study that started in 1995 and includes a postal questionnaire, physical examination, bone density measurement and blood laboratory analyses. Fracture data have been added, and in this report fracture risk and its association with sex hormones was analysed in postmenopausal women without current hormone therapy (HT). A total

TLR7/8 activation in neutrophils impairs immune complex phagocytosis through shedding of FcgRIIA

Neutrophils play a crucial role in host defense. However, neutrophil activation is also linked to autoimmune diseases such as systemic lupus erythematosus (SLE), where nucleic acid-containing immune complexes (IC) drive inflammation. The role of Toll-like receptor (TLR) signaling in processing of SLE ICs and downstream inflammatory neutrophil effector functions is not known. We observed that TLR7/

Aortitis caused by Abiotrophia defectiva: Description of two cases

Abiotrophia defectiva is a well-known endocarditis pathogen, however it has never been described as a cause of primary aortitis. Here we describe the first published case of thoracic aortitis and an unusual case of aortic graft infection due to A. defectiva, which were both managed conservatively.

On a Fire Fighter’s Problem

Suppose that a circular fire spreads in the plane at unit speed. A single fire fighter can build a barrier at speed v>1. How large must v be to ensure that the fire can be contained, and how should the fire fighter proceed? We contribute two results. First, we analyze the natural curve FFv that develops when the fighter keeps building, at speed v, a barrier along the boundary of the expanding fir

Towards an optical diagnostic system for otitis media using a combination of otoscopy and spectroscopy

An improved method, where conventional otoscope investigation of human suspicious otitis media is combined with diffuse reflectance spectroscopy and gas in scattering media absorption spectroscopy (GASMAS) is being developed. Otitis media is one of the most common infectious diseases in children, whose Eustachian tube connecting the middle ear with the nasal cavity is more horizontal than for adul