Published 14 December 2017 December 4-5, nordic researchers gathered in Malmö to discuss future challenges in precision medicine, a research field where diagnosis and treatment are based on the individual´s genetic and biological conditions. Focus is on our common and increasing diseases diabetes, cardiovascular disease, cancer and psychiatric diagnosis. "The goal of the meeting is to bring togeth

https://www.ludc.lu.se/article/nordic-conference-malmo-about-precision-medicine-future - 2025-08-09

Published 2 March 2018 A completely new classification of diabetes which also predicts the risk of serious complications and provides treatment suggestions. We are now seeing the first results of ANDIS – a study covering all newly diagnosed diabetics in southern Sweden — published in The Lancet Diabetes & Endocrinology. The major difference from today’s classification is that type 2 diabetes actua

https://www.ludc.lu.se/article/paradigm-shift-diagnosis-diabetes - 2025-08-09

Published 9 December 2020 Malmö city, Sweden had 322,574 inhabitants in 2015. We used diagnosis registry, charts, and radiographs of the only city hospital to classify fractures in individuals < 16 years in 2014–2016, and compared these with data from 1950–2006. We used joinpoint regression to analyze time trends and present results as mean annual percentage changes (APC). Differences between peri

https://www.lupop.lu.se/article/time-trends-pediatric-fractures-swedish-city-1950-2016 - 2025-08-09

Published 9 December 2020 Two academic centers in Lithuania and Turkey participated in this retrospective study conducted between November 2018 and July 2019. A total of 100 consecutive patients (22 males, 78 females; mean age 78.9 years; range, 45 to 100 years) with low energy proximal femur fractures admitted for surgery were included in the study. Fracture Risk Assessment tool (FRAX) and the Se

https://www.lupop.lu.se/article/combined-fracture-and-mortality-risk-evaluation-stratifying-treatment-hip-fracture-patients - 2025-08-09

Published 10 December 2020 Recent improvements in life expectancy in many countries stem from reduced mortality from cardiovascular disease and cancer above the age of 60. This is the combined result of decreased incidence and improved survival among those with disease. The latter has led to a higher proportion in the population of people with a past history of disease. This is a group with higher

https://www.lupop.lu.se/article/rise-number-long-term-survivors-different-diseases-can-slow-increase-life-expectancy-total - 2025-08-09

Published 10 December 2020 Global environmental change has degraded ecosystems. Challenges such as climate change, resource depletion (with its huge implications for human health and wellbeing), and persistent social inequalities in health have been identified as global public health issues with implications for both communicable and noncommunicable diseases. This contributes to pressure on health

https://www.lupop.lu.se/article/advancing-global-health-through-environmental-and-public-health-tracking-0 - 2025-08-09

Published 11 December 2020 International patient registries are of particular importance for rare disorders, as they may contribute to overcome the lack of knowledge derived from low number of patients and limited awareness of these diseases, and help to learn more about their geographical or population-based specificities, which is relevant for research purposes and for promoting better standards

https://www.lupop.lu.se/article/creation-and-implementation-european-registry-patients-mcardle-disease-and-other-muscle-glycogenoses - 2025-08-09

Published 11 December 2020 Dominant mutations in valosin-containing protein (VCP) gene cause an adult onset inclusion body myopathy, Paget’s disease of bone, and frontotemporal dementia also termed multisystem proteinopathy (MSP). The genotype-phenotype relationships in VCP-related MSP are still being defined; in order to understand this better, we investigated the phenotypic diversity and pattern

https://www.lupop.lu.se/article/phenotypic-diversity-international-cure-vcp-disease-registry - 2025-08-09

Published 12 December 2020 The COVID-19 pandemic may have severe impact on mental health, and concerns have been raised about potentially increased online behavior and possibly increased gambling problems, such as in sports bettors at risk of transfer to even riskier forms of gambling during sports lock-down. Given the need for objective data about gambling behavior during the pandemic, the presen

https://www.lupop.lu.se/article/impact-covid-19-online-gambling-general-population-survey-during-pandemic - 2025-08-09

Published 12 December 2020 Survival data for pancreatic cancer are usually based on actuarial calculations and actual long-term survival rates are rarely reported. Here we use population-level data from the Surveillance, Epidemiology, and End Results program for patients with microscopically confirmed pancreatic ductal adenocarcinoma diagnosed from 1975 to 2011. A total of 84,275 patients with at

https://www.lupop.lu.se/article/actual-5-year-survivors-pancreatic-ductal-adenocarcinoma-based-real-world-data - 2025-08-09

Published 13 December 2020 The aim of this study was to investigate the appearance of a disturbed oropharyngeal microbiota during hospitalization and explore the patient characteristics that maybe associated with such a disturbance. Oropharyngeal swabs were collected from 134 patients at hospital admission and every 3–4 days thereafter. The samples were cultivated to determine the presence of a di

https://www.lupop.lu.se/article/disturbance-oropharyngeal-microbiota-relation-antibiotic-and-proton-pump-inhibitor-medication-and - 2025-08-09

Published 13 December 2020 Only one fifth of children aged 11–17 years are physically active for 60 min (min)/day. As physical activity (PA) levels track from childhood to adulthood, it is important to establish healthy PA behavior early in life. This study aims to evaluate whether daily school PA is associated with objectively measured PA independently of other socioecological factors. This study

https://www.lupop.lu.se/article/daily-school-physical-activity-associated-higher-level-physical-activity-independently-other - 2025-08-09

Published 14 December 2020 The Swedish Quality Register for Inflammatory Bowel Disease (SWIBREG) contains clinical data for the study of inflammatory bowel disease (IBD). The Epidemiology Strengthened by histoPathology Reports in Sweden (ESPRESSO) cohort was recently established for the study of gastrointestinal histopathology. We aimed to develop and validate a histology score from ESPRESSO using

https://www.lupop.lu.se/article/novel-method-quantifying-intestinal-inflammatory-burden-inflammatory-bowel-disease-using-register - 2025-08-09

Published 14 December 2020 Read more at Current national hand surgery registries worldwide - PubMed (nih.gov)

https://www.lupop.lu.se/article/current-national-hand-surgery-registries-worldwide - 2025-08-09

Published 15 December 2020 We are living in a multi-omics era of systems epidemiology. Quantitative high-throughput metabolomics and lipidomics have resulted in hundreds of molecular measures for up to tens of thousands of people in multiple cohorts and biobanks. Extensive and complex data create significant challenges for statistical analyses. It would therefore be beneficial, not only for omics

https://www.lupop.lu.se/article/epimetal-open-source-graphical-web-browser-tool-easy-statistical-analyses-epidemiology-and - 2025-08-09

Published 15 December 2020 Read more at EuroHeart: European Unified Registries On Heart Care Evaluation and Randomized Trials - PubMed (nih.gov)

https://www.lupop.lu.se/article/euroheart-european-unified-registries-heart-care-evaluation-and-randomized-trials-0 - 2025-08-09

Published 16 December 2020 Read more at Moving breast implant registries forward: Are they FAIR and Functional? - PubMed (nih.gov)

https://www.lupop.lu.se/article/moving-breast-implant-registries-forward-are-they-fair-and-functional - 2025-08-09

Published 16 December 2020 Good data curation is integral to cohort studies, but it is not always done to a level necessary to ensure the longevity of the data a study holds. In this opinion paper, we introduce the concept of data curation debt—the data curation equivalent to the software engineering principle of technical debt. Using the context of UK cohort studies, we define data curation debt—

https://www.lupop.lu.se/article/recognizing-reporting-and-reducing-data-curation-debt-cohort-studies - 2025-08-09

Published 17 December 2020 In Denmark, vaccination coverage is measured using the Danish Vaccination Register (DDV). In general, the vaccination coverage is high, but for some vaccinations, the coverage is suboptimal with geographical variation. This study aims to validate the vaccination coverage of the 5-year booster and identify overall reasons for non-vaccination in Copenhagen. Read more at Un

https://www.lupop.lu.se/article/underreporting-5-year-tetanus-diphtheria-pertussis-and-polio-booster-vaccination-danish-vaccination - 2025-08-09

Published 17 December 2020 Evidence-based information available at the point of care improves patient care outcomes. Online knowledge bases can increase the application of evidence-based medicine and influence patient outcome data which may be captured in quality registries. The aim of this study was to explore the effect of use of an online knowledge base on patient experiences and health care qu

https://www.lupop.lu.se/article/use-online-knowledge-base-primary-health-care-and-correlation-health-care-quality-observational - 2025-08-09