Dopamine-producing neurons that researchers from Lund University have grown in the laboratory from human embryonic stem cells (Photo: Agneta Kirby) An investigational stem cell-based therapy for the treatment of Parkinson’s Disease, STEM-PD, has been given regulatory approval for a Phase I/IIa clinical trial. Ethical approval of the trial has already been obtained from the Swedish Ethics Review Au

https://www.stemcellcenter.lu.se/article/swedish-medical-products-agency-grants-approval-clinical-study-new-stem-cell-based-parkinsons - 2025-08-25

Image: Clement Da Silva B cells and the antibodies they produce play an important role in our immune system, protecting us from the microscopic enemies that make us ill. Uncovering how they form and are ‘programmed’ during development is key to better understanding the immune response to infections and vaccinations. A new study by researchers from Lund Stem Cell Center at Lund University in Sweden

https://www.stemcellcenter.lu.se/article/how-b-cells-are-programmed-early-life-can-impact-long-term-immune-health - 2025-08-25

Simon Hultmark defended his Ph.D. thesis on 06 October 2022. Earlier this month, Simon Hultmark defended his Ph.D. thesis. In pursuit of his long-standing fascination for stem cells, his research over the last several years has focused on blood stem cells and cancer. All in an effort to contribute to the development of improved clinical therapies for patients with a type of blood cancer known as a

https://www.stemcellcenter.lu.se/article/modeling-normal-and-malignant-hematopoiesis-vitro-phd-interview-simon-hultmark - 2025-08-25

Laura Duran Lozano defended her Ph.D. thesis “Genetic predisposition for Multiple Myeloma. Identification and functional characterization of risk variants” on Friday, 21 October 2022. At the end of October Laura Duran Lozano successfully defended her Ph.D. thesis. Motivated by the idea of helping patients and families impacted by cancer, and as part of the EU CanFaster Program, she has spent the p

https://www.stemcellcenter.lu.se/article/uncovering-genetic-risk-factors-multiple-myeloma-phd-interview-laura-duran-lozano - 2025-08-25

Eight researchers from Lund Stem Cell Center at Lund University have been awarded 41.4 million SEK in the latest announcements from the Swedish Research Council. This funding will support biomedical research on aging, health, disease, and bioengineering over the next several years. Stem cells are the building blocks of modern medicine and hold the key to tackling some of the most complex diseases

https://www.stemcellcenter.lu.se/article/stem-cell-research-aging-health-and-disease-gets-funding-boost-swedish-research-council - 2025-08-25

Principal Investigator Christopher Douse and the Epigenetics and Chromatin Dynamics research group join Lund Stem Cell Center, where they will explore the control and influence of ‘genomic dark matter’ in human brain development. Motivated by fundamental questions about mechanisms underpinning human disease, Christopher Douse’s research interests have gradually shifted from the natural sciences to

https://www.stemcellcenter.lu.se/article/new-research-group-led-christopher-douse-joins-lund-stem-cell-center - 2025-08-25

Kristijonas Zemaitis defends his Ph.D. thesis on 20 December, 2022. On 20 December, 2022 Kristijonas Zemaitis will defend his Ph.D. thesis. With the goal to improve the availability of human hematopoietic stem cells (HSCs) for the treatment of patients with blood disorders, he has spent the past several years working to better understand HSCs and how they are regulated to one day propagate these s

https://www.stemcellcenter.lu.se/article/unravelling-mechanisms-blood-stem-cell-expansion-phd-interview-kristijonas-zemaitis - 2025-08-25

Earlier this fall, the Swedish Cancer Foundation (Cancerfonden) distributed 133 million SEK to 41 cancer researchers at Lund University. Nearly a quarter of this - 28 million SEK - has been awarded to 11 researchers from Lund Stem Cell Center, funding translational research which seeks to advance cancer diagnosis, treatment, and prevention. Isabella Artner, Associate Professor, is among the 11 res

https://www.stemcellcenter.lu.se/article/funding-basic-science-advance-cancer-research-cancerfonden-distributes-28-million-sek-lund-stem-cell - 2025-08-25

Immunofluorescence image of lab generated human ossicles or mini bones. Image credit: Dr. Dimitra Zacharaki Researchers at Lund University and Lund Stem Cell Center have generated human mini bones in the lab which mirror the composition and function of human bone. The results published in Science Translational Medicine detail this step toward the future development of patient-tailored, personalize

https://www.stemcellcenter.lu.se/article/toward-personalized-approach-study-and-treatment-bone-cancers - 2025-08-25

Control (right) and treated (left). Image credit: Francesco Trovato. Lund Stem Cell Center researchers from Lund University and Skåne University Hospital have uncovered a way to impair the growth and progression of glioblastoma tumor cells - the most aggressive form of brain cancer. The study, published in Molecular Cancer Therapeutics, shows it is possible to transform these cancer cells into cel

https://www.stemcellcenter.lu.se/article/reprogramming-cancer-cells-impair-glioblastoma-growth - 2025-08-25

Principal Investigator, Filipe Pereira. Photo: Kennet Ruona. Professor Filipe Pereira, researcher at the Lund Stem Cell Center, is the principal investigator of one of two innovation-driven research initiatives at Lund University to receive a Proof of Concept Grant from the European Research Council (ERC). The goal of the project is to harness a new technology to enable powerful and targeted thera

https://www.stemcellcenter.lu.se/article/erc-grant-supports-new-innovative-advancements-immunotherapy-research - 2025-08-25

While it is well known that men and women have different health needs, have you ever considered why? The Systems Immunology research group, led by Camila Consiglio, has. Together, Lund Stem Cell Center’s newest members are working to uncover whether the answer lies in the differences between the female and male immune systems. “At the heart of our research is the question: how can we understand th

https://www.stemcellcenter.lu.se/article/unveiling-gender-gap-immunity-camila-consiglio-joins-lund-stem-cell-center - 2025-08-25

Jiao Dong defended her Ph.D. thesis on the 8th of February 2023. Inspired by the memory of patients she met during her time as a student studying oral surgery in China, she has spent the past four years researching a regenerative medicine strategy that can be used to repair the function of the salivary gland. In this interview, we learn more about her innovative research efforts, the inspiration b

https://www.stemcellcenter.lu.se/article/bioengineering-and-cell-derived-strategies-salivary-gland-regeneration-phd-interview-jiao-dong - 2025-08-25

Last month, Ella Quist defended her Ph.D. thesis. After beginning her research journey as a master’s student within our Ph.D. Preparatory Program, she dedicated the last several years to developing more efficient methods that can be used to generate functional and mature astrocytes for disease modeling of neurological disorders. In this interview, we learn more about her efforts to facilitate futu

https://www.stemcellcenter.lu.se/article/generating-human-astrocytes-disease-modeling-phd-interview-ella-quist - 2025-08-25

Bildkälla: iStock/Pedre During the fetal stage, a number of so-called cell programs run that are vital to the development of the fetus. In a study published in Cell Reports, researchers from Lund Stem Cell Center at Lund University demonstrate that one of these fetal programs appears to protect against acute myeloid leukaemia (AML). “We have used an experimental mouse model that always results in

https://www.stemcellcenter.lu.se/article/new-insights-fetal-development-may-protect-against-leukaemia - 2025-08-25

Hani Alsafadi defended his Ph.D. thesis on the 13th of February, 2023. With a longstanding interest in biomedical research and a passion for better understanding one of the least regenerative organs in the body, the lung, he has spent the past four years helping to uncover some of the mechanisms that may drive a lung disease currently without a cure, idiopathic pulmonary fibrosis. In this intervie

https://www.stemcellcenter.lu.se/article/exploring-role-yap-and-taz-lung-epithelium-phd-interview-hani-alsafadi - 2025-08-25

​​​​​​​Did you know that about 70% of rare diseases begin in childhood? How about that 1 in 5 cancers are considered a rare disease? Or that nearly three-quarters of all rare diseases are genetic diseases? With more than 6,000 rare diseases known to impact the lives of an estimated 300 million people around the world – rare diseases are all too common. Limited knowledge of these diseases often res

https://www.stemcellcenter.lu.se/article/shining-spotlight-rare-disease-research - 2025-08-25

On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed by Lund Stem Cell Center researchers at Lund University and it is now being tested in patients for the first time. The transplantation product is generated from embryonic stem cells and functions to replace the dopamin

https://www.stemcellcenter.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease - 2025-08-25

On 03 March 2023, Jenny Mattsson defended her Ph.D. thesis. With the goal to broaden the availability of antibody-based drugs for patients with cancer and other diseases, she has spent the past several years working to develop new methods that can be used to identify new antibodies and antibody targets. In this interview, we learn more about her research, how she has simultaneously juggled doing a

https://www.stemcellcenter.lu.se/article/new-methods-phenotypic-antibody-discovery-phd-interview-jenny-mattsson - 2025-08-25

Highschool students learn how the extraordinary regenerative powers of salamanders can help us discover new ways to fight diseases in humans in a UniStem Day 2023 workshop led by researchers in the Leigh Group. Have you ever wondered what it takes to grow a brain in a petri dish or how scientists use viruses to fight genetic diseases? These are just some of the fascinating topics explored on UniSt

https://www.stemcellcenter.lu.se/article/inspiring-tomorrows-scientists - 2025-08-25