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Psychostimulant Effects on Motor and Cognitive Function in Adults Attention Deficit Hyperactivity Disorder (ADHD)

OBJECTIVES: This study aims to compare the performance on motor and cognitive functions of adult patients with attention deficit hyperactivity disorder (ADHD) with or without psychostimulant medication, and controls. A secondary objective is to investigate differences on test performance across varying levels of disorder severity.METHODS: We included patients with unmedicated ADHD (n=52), patients

Childhood Neighborhoods and Life-Time Fertility in Twentieth-Century Sweden. A k-Nearest Neighbor Approach

In addition to the family context, persons in the neighborhood and community are important for individual life course, socioeconomic and demographic outcomes such as education, career and family transitions. This paper aims to study how neighborhood conditions in childhood influence fertility outcomes in adulthood. Theories focusing on motivation, aspirations and attitudes or peer influence generaIn addition to the family context, persons in the neighborhood and community are important for individual life course, socioeconomic and demographic outcomes such as education, career and family transitions. This paper aims to study how neighborhood conditions in childhood influence fertility outcomes in adulthood. Theories focusing on motivation, aspirations and attitudes or peer influence genera

Design och utveckling av ett avtagbart elektronik hölje för en smart textil

Detta examensarbete genomfördes i nära samarbete med Donya Tech AB, som utvecklar ett smart graviditetsband som följer fosterrörelser. Syftet med arbetet är att utveckla ett avtagbart elektronikhölje som ska integreras i plagget och skyddar den elektronik som används. Arbetet har utgått från Ulrich och Eppinger´s produktutvecklingsprocess i kombination med Rapid Prototyping, vilket möjliggjorde enThis master thesis project was carried out in close collaboration with Donya Tech AB, who are developing a smart pregnancy band that monitors fetal movements. The aim of the project is to develop a removable electronic housing that will be integrated into the garment and protect its components. The work has been based on Ulrich and Eppinger’s Product Development Process in a combination with Rapid

Praktiker kring vårdträd

This thesis examines the practices and importance of the “care-tree” (vårdträd) for human-nature relations in Sweden during the 19th and early 20th centuries. The “care-tree” have a long history of use, are entwined with supernatural beliefs, and are said to reflect the well-being and luckiness of the yard where it’s planted. Using theories of social control, non-human agencies and the dwelling pe

A genome- and phenome-wide association study of plasma procalcitonin concentrations in individuals of European ancestry

Background: Procalcitonin (PCT) is a biomarker used to differentiate between viral and bacterial infections, though the underlying mechanisms are not yet fully understood. This study aimed to identify genetic variants associated with plasma PCT concentrations and explore the associations of genetically predicted PCT with a wide range of disease related traits in a PheWAS. Methods: We conducted GWA

Depth-Wise Changes in Tibial and Femoral Human Knee Joint Cartilage at Different Severities of Osteoarthritis

Articular cartilage undergoes structural and compositional changes during osteoarthritis (OA), one of the most common joint diseases. Earlier research shows that these changes are dependent on species and joint site, and they also vary across cartilage depth. In this study, we analyzed the depth-wise proteoglycan and collagen contents, as well as collagen fibril orientation angle and fibril alignm

JNK-regulated phosphoproteome links synaptic and metabolic pathways to mood regulation

c-Jun N-terminal kinases (JNKs) are implicated in both neurodegeneration and mood regulation, including anxiety and depressive-like behaviours. Yet the consequences of JNK inhibition in vivo on protein phosphorylation in the brain remain largely unknown. This study aimed to (1) determine how chronic JNK inhibition altered proteome-wide phosphorylation in hippocampus and nucleus accumbens, regions

A collaborative approach to the evaluation of cognitive accessibility of a conversational agent for public healthcare

Conversational agents are increasingly being introduced in healthcare to enhance access to healthcare and address limited healthcare resources. The aim of this study was to explore experiences of a conversational agent for symptom checking and triage tool assessing the urgency and appropriate level of care implemented in public healthcare from a cognitive accessibility perspective. With a Particip

Electrocardiographs before 1910 : Manufacturers and surviving instruments

Background: Early electrocardiograph predates electronic amplification and therefore required innovative and highly sensitive instrumentation. Willem Einthoven's introduction of the string galvanometer in 1903 enabled recording of clinically useful electrocardiograms and established electrocardiography as a diagnostic method. Objectives: To describe the provenance and technical features of a uniqu

Effects of experimentally manipulating group size on cognitive performance in red junglefowl chicks

Determining the drivers of intraspecific variation in cognitive performance is crucial for understanding how cognition evolves, but experimental studies are scarce. Several correlational studies have supported the hypothesis that living in larger groups enhances cognitive performance. However, empirical explanations of whether and how living in large groups causally affects individual cognitive pe

Adverse Muscle Composition Is an Early Feature of Chronic Kidney Disease and Associates With Poor Function and Comorbidities

Rational & Objective: Sarcopenia is linked to increased morbidity and mortality in chronic kidney disease (CKD), but its definition and assessment vary considerably across studies. This study evaluated the technical feasibility of magnetic resonance imaging (MRI)–based assessment of adverse muscle composition (AMC)—defined as low muscle volume and high fat infiltration—and its associations wit

Electrophysiological analysis and computational modelling of dendritic processing by feature detection neurons in insects

Many insects have a behavioral need for the rapid detection of small moving visual targets. In dragonflies and flies, Small Target Motion Detector (STMD) neurons have been found to fill this function, but observations in Hymenopterans raise questions of whether similar neurons are present. In high order variants of these neurons, predictive response gain modulation thought to be driven by dendriti