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gamma -Carboxylated proteins were detected in normal human pancreas by immunohistochemistry with a monoclonal antibody (M3B) specific for gamma -carboxyglutamyl residues, Staining appeared to be localized to the glucagon-secreting alpha -cells in the islets of Langerhans, Consistent with this, sections from a glucagonoma were stained much more intensely with the M3B antibody than those from an ins
We introduce a new notion of independence based on the Borel-Cantelli lemma. We study this characteristic in the context of i.i.d. stochastic processes and processes driven by equilibrium dynamics.
Background: To evaluate and describe the cone function in the normal and lesioned rabbit retina using the multifocal electroretinogram (mfERG). Methods: Twelve animals underwent a two-port vitrectomy with subsequent retinectomy in one eye. The area of removed retina was located in the nasal part of the visual streak, and measured approximately 1-2 disc diameters. Both eyes were investigated with m
OBJECTIVES: to evaluate the long-term results of stenting in iliac and aortic occlusive disease and identify factors predicting clinical outcome. Design: retrospective study. MATERIALS AND METHODS: 82 patients (87 limbs) with stenoses (n =63) and occlusions (n =24) in the aortoiliac segment were treated with stents. 81 lesions involved the iliac arteries, 3 the infrarenal aorta and 3 the aortic bi
Ring species, which consist of two reproductively isolated forms connected by a chain of intergrading populations, have often been described as examples of speciation despite gene flow between populations, but this has never been demonstrated. We used amplified fragment length polymorphism (AFLP) markers to study gene flow in greenish warblers (Phylloscopus trochiloides). These genetic markers sho
Egg and clutch size variation among populations of common frogs (Rana temporaria) were studied in 14 ponds in Sweden. Also two secondary indices, clutch mass and allocation tactics (egg size3/clutch size) were studied. For all four characters there was a pond-wise correlation between the values across the two study years. All characters differed among ponds and all but allocation tactics differed
Background - Although effective coverage of challenging coronary lesions has warranted the use of overlapping drug-eluting stents, the histopathological response to stent overlap is unknown. Methods and Results - The arterial reaction to overlapping Cypher or Taxus drug-eluting stents was examined in rabbits with bare metal stents, BxVelocity or Express, serving as controls. Single iliac artery ba
Electrochromic devices have the ability to produce reversible and persistent changes of their optical properties. The phenomenon is associated with joint ion and electron transport into/out of an electrochromic thin film, in most cases being a transition metal oxide. This paper outlines the various applications of such devices in smart windows suitable for energy-conscious architecture, in variabl
A search for pair-produced doubly charged Higgs bosons has been performed using the data collected by the DELPHI detector at LEP at centre-of-mass energies between 189 and 209 GeV. No excess is observed in the data with respect to the Standard Model background. A lower limit for the mass of 97.3 GeV/c(2) at the 95% confidence level has been set for doubly charged Higgs bosons in left-right symmetr
A task-oriented system structure has been developed. In normal industrial robot programming, the path is created and the process is based on the path. Here a process-focused method is proposed, where a task can be split in subtasks, one for each part of the process with similar process-characteristics. By carefully encapsulating the information needed to execute a sub-task, this component can be r
Objective To describe the gray-scale and color Doppler ultrasound findings of metastatic tumors in the ovary according to the origin of the primary tumor. Methods Information was retrieved retrospectively from 67 patients who had undergone preoperative transvaginal gray-scale and color Doppler ultrasound examination and who were found subsequently to have metastatic tumors in their ovaries. In all
We investigate the symmetry of magnetoconductance fluctuations of phase-coherent, two-terminal quantum dots in the nonlinear regime of transport. Specifically, we consider open, ballistic quantum dots (electron billiards) with and without symmetry axes parallel and perpendicular to the current direction and formulate a set of novel symmetry relations not observed in devices with lower symmetry. We
Malaria, Antimalariamedel, Mikrobiell läkemedelsresistens, Världhälsoorganisationen, Plasmodium falciparum
Background: The cell surface glycoprotein E-cadherin (CDH1) is a key regulator of adhesive properties in epithelial cells. Germline mutations in CDH1 are well established as the defects underlying hereditary diffuse gastric cancer (HDGC) syndrome, and an increased risk of lobular breast cancer (LBC) has been described in HDGC kindreds. However, germline CDH1 mutations have not been described in pa
