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Non-invasive MRI is widely used to assess and monitor ischemic stroke, yet conventional approaches often lack sensitivity to subtle microstructural changes and struggle to evaluate tissue viability across lesion, penumbra, and distal regions. In this study, frequency dependent diffusion tensor distribution imaging (ωDTD) was combined with clustering of diffusion tensor distributions D(ω) and multi
Co-pathology is a common feature of neurodegenerative diseases that complicates diagnosis, treatment and clinical management. However, sensitive, specific and scalable biomarkers for in vivo pathological diagnosis are not available for most neurodegenerative neuropathologies. Here we present Proteomics-based Artificial Intelligence for Dementia Diagnosis (ProtAIDe-Dx), a deep joint-learning model
The lack of research on why certain locations are perceived as unsafe has often been attributed to the scarcity of suitable data on place-based fear of crime. To address this gap, this study explores two spatial data collection methods applied in semi-rural areas of Kristianstad, Sweden. The first method uses a digital sketch map integrated with open-ended questions, accessed via an online web map
We present results of Population III (Pop III) formation in the megatron suite of simulations, which self-consistently follows radiation and non-equilibrium chemistry, and resolves gas at near-pc resolution in a Milky Way-mass progenitor at Cosmic Dawn. While the very first Pop III stars form in haloes with masses well below the atomic cooling limit, the majority of Pop III stars form in more mass
We develop and test a model of social duties. The model distinguishes unconditional duties to take or avoid certain actions from conditional duties that depend on the actions’ payoffs. It also distinguishes strict duties (must do) from liberal duties (ought to do). The disutility associated with duty violation depends on the duty’s strictness and is proportional to the externality the violation ca
Introduction: Cervical cancer represents a significant public health challenge worldwide. To improve screening accessibility and participation, we implemented vaginal human papilloma virus (HPV) self-sampling as part of an organized cervical cancer prevention strategy. This study aimed to evaluate the implementation and outcomes of the self-sampling program in a real-world setting. Material and Me
Sensitivity measures how much the output of an algorithm changes, in terms of Hamming distance, when part of the input is modified. While approximation algorithms with low sensitivity have been developed for many problems, no sensitivity lower bounds were previously known for approximation algorithms. In this work, we establish the first polynomial lower bound on the sensitivity of (randomized) ap
We study the design of efficient approximation algorithms for the ℓ-center clustering and minimum-diameter ℓ-clustering problems in high-dimensional Euclidean and Hamming spaces. Our main tool is randomized dimension reduction. First, we present a general method of reducing the dependency of the running time of a hypothetical algorithm for the ℓ-center problem in a high-dimensional Euclidean space
The Quercetum Chorus Workshop introduced students in the Cal Poly Pomona Interdisciplinary Paris Study Abroad Program (CPP IPSAP) to methods of deepening human-tree relations through sound, drawing and movement. Students applied a multi-sensory approach to knowing trees by attuning to their frequencies, textures, shapes, and movements. They were invited to reimagine trees as more-than-human bodies
Jeffrey Breau of Harvard University and Natalie Bloch, Research Fellow at Lund University, discuss how psychedelic experiences are interpreted within religious traditions, with particular attention to Judaism and the emergence of new psychedelic churches in the United States.Their conversation explores how these experiences are shaped by cultural frameworks and by ongoing debates between perennial
Traumatic brain injury (TBI) is commonly associated with white matter injury, leading to persistent symptoms and long-term disability. While advanced age is linked to worse outcome post-TBI, the influence of sex remains highly controversial. The present study aimed to identify age- and sex-dependent differences in white matter pathology during the chronic phase of TBI using the central (midline) f
A blood group may be defined as an inherited character of the red cell surface detected by a specific alloantibody. This definition would not receive universal acceptance, since cell surface antigens on platelets and leucocytes might also be considered blood groups (see Chapter 4), as might acquired characteristics on red cells defined by autoantibodies or polyagglutinins. The definition is suitab
Spin crossover (SCO) complexes are highly promising candidates for a myriad of potential applications in room-temperature electronics; however, as it stands, establishing a clear connection between their spin-state switching and transport properties has been far from trivial. In this perspective, an effort to unravel the underlying charge transport mechanism in these SCO complexes, via a general t
Traumatic brain injury and stroke often result in contralateral sensorimotor deficits, including asymmetric posture. While these lateralized effects are classically attributed to neural tract disruption, recent evidence supports the existence of a complementary humoral pathway. Our previous work demonstrated that the neurohormone Arg-vasopressin (AVP) mediates right hindlimb responses to left-side
Studying the full universe of nearly 390,000 French patents filed between 1791 and 1900, I show that the nineteenth-century gender patenting gap arose less at the patent office than through unequal access to practical knowledge, collaborators, and time across the life course. I identify 4,165 women inventors using gender-specific honorifics, classify patents with machine learning, reconstruct the
PurposeThis study aims to assess the diffusion and integration of Circular Economy (CE) knowledge across academic disciplines, by examining how CE concepts spread within mainstream academic and disciplinary discourses.Design/Methodology/ApproachCE is conceptualized as a knowledge object, distinguishing between mainstream academic discourse (MAD) and mainstream disciplinary discourse (MDD). The res
Background: Adolescents are increasingly using classical psychedelics, yet little is known about how psychedelics use is related to their mental health. Emerging evidence suggests that adolescents may be more vulnerable to adverse outcomes in relation to psychedelic use compared to adults. This descriptive and exploratory study examined differences between adolescents and adults in reported psyche
The demand for safe and durable modified-wood products is increasing in the construction sector. In this work, the in situ wet-chemistry synthesis of a glassy MgO/Na2O–SiO2 solid in Scots pine (Pinus sylvestris L.) sapwood via a two-stage impregnation process using an industrial timber-impregnation autoclave is reported. Magnesium sulphate heptahydrate (MgSO4·7H2O), a historic fire retardant, and
