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Under sustained global warming, Arctic climate is projected to become more responsive to changes in North Pacific meridional heat transport as a result of teleconnections between low and high latitudes, but the underlying mechanisms remain poorly understood. Here, we reconstruct subarctic humidity changes over the past 400 kyr to investigate the role of low-to-high latitude interactions in regulat
Cross-country regressions suggest that protectionism supported industrialization. I leverage novel and highly granular data covering Swedish manufacturing firms to estimate the impact of Sweden’s shift toward protectionism after 1891 on establishment-level development. Using mainly two-way fixed effects regressions, I show that tariff increases had a heterogeneous impact across establishments: ini
Conversational theatre is a medium for facilitating dialog on race, privilege, and discrimination in Swedish society. Du Contrat Social, a performance based on Jean-Jacques Rousseau's social contract, demonstrates how theatre can create an interactive space where audience members actively reflect on their social positioning and implicit biases. By guiding the audience through exercises that expose
High Performance Research Desktops are used by HPC centers and research computing organizations to lower the barrier of entry to HPC systems. These Linux desktops are deployed alongside HPC systems, leveraging the investments in HPC compute and storage infrastructure. By serving as a gateway to HPC systems they provide users with an environment to perform setup and infrastructure tasks related to
The increasing threat of soil degradation presents significant challenges to soil health, especially within agroecosystems that are vital for food security, climate regulation, and economic stability. This growing concern arises from intricate interactions between land use practices and climatic conditions, which, if not addressed, could jeopardize sustainable development and environmental resilie
Considering the distinct etiological pathways and molecular characteristics of different lung cancer subtypes, it is crucial to develop subtype-specific prevention strategies and therapeutic targets. This study aimed to identify protein biomarkers and potential therapeutic targets for specific subtypes of lung cancer by integrating population-based observational studies and Mendelian randomisation
Background: Air pollution has been linked to breast cancer risk, but previous studies have seldom considered specific exposure windows, like pregnancy. During pregnancy the breast undergoes substantial changes and exposures may have a stronger impact than if they occurred during other time periods. This study aims to identify associations between ambient air pollution exposure during pregnancy and
Purpose of Review: Summarize recent literature on: understanding of and emotional reactions to type 1 diabetes (T1D) risk; willingness to be screened; behavioral responses to T1D-risk screening results; and provider attitudes/concerns about general population screening. Recent Findings: Difficulty understanding what it means to be at increased risk for T1D is common; anxiety about increased risk m
Chronic exposure to second-hand smoke (SHS) contributes to the development of health issues, including cancer and cardiovascular diseases. Molecular mechanisms underlying SHS-related diseases remain poorly understood, highlighting the need for reliable risk assessment biomarkers. Herein, we demonstrate that the plasma proteome of individuals exposed to SHS undergoes significant modulation. Butyryl
This study introduces a novel approach for synthesising a surface-imprinted polymer-ordered mesoporous silica adsorbent, known as SiO2@MIPs-CAPcr, with high selectivity for chloramphenicol (CAP) adsorption by employing an activator that was regenerated by electron atom transfer radical polymerisation (ARGET ATRP). Optimal synthesising conditions for SiO2@MIPs-CAPcr have been determined, including
Purpose: The Paleolithic Diet Fraction (PDF) estimates the proportion of absolute dietary intake derived from food groups included in the Paleolithic diet. In the Malmö Diet and Cancer Study (MDCS), higher PDF and lower systemic low-grade chronic inflammation (SLGCI) have been associated with lower cardiometabolic morbidity and mortality. We examined associations between PDF and SLGCI in the MDCS.
Hypertrophic cardiomyopathy (HCM), the most common inherited cardiomyopathy, is characterized by phenotypic and genetic heterogeneity. The present study describes the genotype data of a Swedish cohort of patients with HCM, the largest genetics study on Swedish HCM patients to date. The primary aims of this study were to unravel the main genetic findings and explore genotype–phenotype associations
Introduction: Mycobacteria have a unique hydrophobic membrane with several lipid-enriched layers that are low in permeability, setting them apart from other bacteria. This complex structure, consisting of three distinct layers is crucial for cell growth, virulence, and providing a barrier to antibiotics. Previously, we identified a plectasin variant, NZX, which showed activity against Mycobacteriu
Background: Optimal long-term follow-up (LTFU) care for survivors of childhood, adolescent and young adult (CAYA) cancer can improve or maintain their quality of life by prevention and early treatment of late effects. However, optimal LTFU care is not provided to all CAYA cancer survivors. This systematic review sought to identify associated barriers, facilitators and other factors of LTFU care fo
This joint article, comprising five contributions, results from a workshop focused on the use of Bible commentaries in teaching at Swedish universities today. While each contribution presents a distinct style and voice, we all agree on the importance of learning how to use commentaries in higher education and, equally, the need for their active application. We also all welcome the development of m
In recent years, there has been an increasingly larger fraction of intermittent energy sources. In the northern parts of Europe, the main source of intermittent power is wind power. This source of power is low inertia, inconsistent and will always fluctuate with different magnitudes, leaving a need for balancing. One source of balancing is to have the widespread non-zero inertia combined heat and
Aims: Economic simulation models, such as the IHE Type 2 Diabetes Cohort Model (IHE-DCM-T2), are used widely to inform resource allocation for Type 2 Diabetes (T2D) treatments. Recently, IHE-DCM-T2 was augmented with Japanese-specific risk equations to align with the Japanese healthcare context. This study extends prior model validation of IHE-DCM-T2 to cover the Japanese risk equations for applic
The relevance of institutions for regional development has been well established in economic geography. In this context, local and regional governments play a central role, particularly through place-based and place-sensitive strategies. However, systematic and scalable insights into their priorities and strategies remain limited due to data availability. This paper develops a methodological appro
