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BACKGROUND AND AIM: The genetic basis of Metabolic syndrome (MetS) is largely unknown but a link with salt sensitivity is recognized. The cytochrome P450 isoform 4F2 (CYP4F2) is involved in renal production of 20-hydroxyeicosatethraenoic acid (20-HETE), a natriuretic substance associated with salt sensitivity. The same enzyme is implicated in ω-hydroxylation of very long and medium chain fatty aci

Nations around the world are feverishly developing new standards relating to Building Information Modelling (BIM) in the construction industry which may enable teams to leverage greater value from BIM implementation and model authorship efforts. This study reflects on ongoing standardisation initiatives in Sweden and considers where current research efforts fit in. There is limited research presen

At the end of the 19th century, Wilhelm Windelband proposed a distinction between nomothetic and idiographic re-search, which became highly relevant for the discussion of the nature of psychological science. During the 20th cen-tury, a number of writers (including William Stern, Gordon Allport, James Lamiell and David Magnusson) have criti-cized the focus on variables rather than persons, and popu

Parathyroid hormone (PTH) is a principal regulator of calcium homeostasis. Previously, we studied single-nucleotide polymorphisms present in the major genes in the PTH pathway (PTH, PTHrP, PTHR1, PTHR2) in relation to bone mineral density (BMD) and fracture incidence. We found that haplotypes of the PTH gene were associated with fracture risk independent of BMD. In the present study, we evaluated

Open surgical total aortic arch replacement is a demanding procedure which carries a substantial morbidity and mortality. A less invasive endovascular option is endovascular stent grafting using in situ fenestrations. After thoracic stent graft deployment in the arch, fenestrations are made for the major arch vessels. During this procedure, antegrad cerebral perfusion is maintained using a tempora

Artikel om svartlistningen av filmarbetare i den amerikanska filmindustrin på 1940- och 1950-talen men också om dess eftermäle under 1960-talet.

This paper presents the results of a study where the effects of introducing code reviews in an organisational unit have been evaluated. The study was performed in an ongoing commercial project, mainly through interviews with developers and an experiment where the effects of introducing code reviews were measured. Two different checklist-based review methods have been evaluated. The objectives of t

Background: On-demand therapy with esomeprazole is effective for long-term treatment of non-erosive gastro-oesophageal reflux disease, but it has not been evaluated in erosive gastro-oesophageal reflux disease. Aims: To compare endoscopic and symptomatic remission over a 6-month period when patients with healed erosive gastro-oesophageal reflux disease are treated with esomeprazole 20 mg, either o