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Importance Long-term follow-up studies regarding the safety of risk-reducing mastectomy (RRM) in terms of cancer risk and surgical complications among women with germline pathogenic variants (gPVs) in BRCA1 or BRCA2 (BRCA1/2) are scarce. Objective To analyze cancer risk and surgical complications after RRM. Design, Setting, and Participants This nationwide cohort study investigated 1208 Swedish wo

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The paper embarks on an exploration of how technological advancements are poised to reshape the landscape of future consumption and marketing practices and extend our understanding of whether this trajectory is potentially leading toward a future digital utopia or a dystopia. Drawing upon the theoretical understanding from Marshall McLuhan, this research investigates the metaverse as a novel techn

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Background: Evidence on the association between systemic glucocorticoid use and colorectal cancer (CRC) risk is limited. This study aimed to determine whether systemic glucocorticoid use is associated with an increased risk of overall CRC (diagnosed at any age) and early-onset CRC (EOCRC; diagnosed before 50 years of age). Methods: A nationwide cohort study (follow-up: 2005–2018) was conducted usi

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Introduction A World Health Organization (WHO) system has recently been introduced to standardize reporting of lymph node fine-needle aspiration biopsy (LN-FNAB) cytopathology. Herein, we analyze its diagnostic performance in a routine setting.Materials and methodsWe reviewed 2274 consecutive lymph node fine-needle aspiration biopsies categorized according to the WHO system. Corresponding histolog

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Hydrological Insights: Synergizing Groundwater Models, Remote Sensing, and AI for Water Sustainability offers an in-depth exploration of hydrological modeling and its cutting-edge advancements, presented across six comprehensive sections. Part I establishes the foundational principles and methodologies of hydrological modeling, while Part II delves into sophisticated techniques and tools that enha

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Partly overlapping feathers form a large part of birds’ wing surfaces, but in many species the outermost feathers split, making each feather function as an independent wing. These feathers are complex structures that evolved to fulfil both aerodynamic and structural functions. Yet relatively little is known about how the profile shape and microstructures of feathers impact aerodynamic performance.

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The Gaussian β-ensemble is a real n-point configuration {xj}n1 picked randomly with respect to the Boltzmann factor e− β 2 Hn, where Hn = ∑i≠j log |xi−1xj| + n ∑ni=112 xi2. It is well known that the point process {xj }n1 tends to follow the semicircle law σ (x) = 21π√(4 − x2 )+ in certain average senses. A Fekete configuration (minimizer of Hn) is spread out in a much more uniform way in the inter

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The article examines Europeanisation processes at the Spanish University of Valladolid (UVa) in the years around Spain’s adhesion to the European Communities in 1986. This event has often been seen as key to the Spanish transition to democracy, which had begun after the death of Francisco Franco in 1975. Drawing on a variety of source materials, the article shows that Europeanisation at the UVa in

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Background: Natural selection can be a potent contributor to speciation, but how exactly this occurs remains unclear. Studying behavioral isolation and the divergence of mating behaviors among multiple isolated populations can help uncover the importance of divergent adaptation in the evolution of reproductive isolation. Here, we utilize common-garden reared virgin Bahamas mosquitofish (Gambusia h

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Declines of insect pollinator diversity in farmlands have neither been halted nor reversed despite large efforts to change the negative trend. One driver of this is agricultural intensification, which has resulted in landscape simplification by loss of non-crop habitats, and increased use of inorganic fertilizers and synthetic pesticides. Consequently, the presence of grazing animals in agricultur

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This chapter critically examines the structural forces shaping the emergence and spread of Emerging Infectious Diseases (EIDs), with a particular focus on avian influenza and the poultry supply chain. Moving beyond conventional epicenter thinking, which attributes disease emergence to specific geographic locations, we argue that EIDs should be understood within broader ecological, economic, social

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Natural resource extraction often takes place in locations where communities are not financially well-off and where historically marginalized groups reside. This paper contributes to the policy debate by revealing how corporate social licence tactics enable a model of corporate-community manipulation which is similar across different geographical contexts. Original data gathered between 2016 and 2

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The subfamily Stiriinae (Lepidoptera, Noctuidae) is a group of ∼160 described moth species, ∼91% of which occur in the Nearctic, with species diversity centered in the deserts, grasslands, and adjacent foothills of the mountain ranges of Mexico. We infer the first species-level phylogeny for the subfamily using 8 protein-coding genes. While some lineages are primarily leaf or flower feeders, the m

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The evolution of male courtship rituals has traditionally been attributed to female mate selection, but may also hinge on male investment strategies in sexually cannibalistic species. In many spiders, males perform energetically costly courtship rituals to increase acceptance by females and minimise the risk of sexual cannibalism. However, due to sperm competition, males may invest less energy whe

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The North-Western Sahara Aquifer System (NWSAS) shared by Libya, Tunisia, and Algeria is one of North Africa’s biggest nonrenewable groundwater storage systems. The management of its resources in a sustainable way will be central to regional stability, food security, and climate resilience. This book chapter discusses how transboundary cooperation along the NWSAS has evolved through facilitation b

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Freshwater lakes are becoming warmer and browner, with poorly known ecosystem consequences. A major unresolved issue is how these changes will affect the feeding rates of predators that regulate top-down trophic cascades. We explored the effects of temperature and browning on the functional response and feeding rates of a keystone predator, the Northern pike Esox lucius. We first derived a simple

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This article examines a gendered reconfiguration in the Japanese empire’s approach to the control of sexually transmitted diseases (STDs) during the Asia-Pacific War (1937–1945), tracing how state surveillance expanded from targeting women, especially sex workers and ‘comfort women’, to also encompass imperial soldiers as potential vectors of infection. This reallocation of scrutiny restructured t

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How do you govern a university to make it effective in the real world? This informative book explores the increasingly complex challenges in governing and managing contemporary universities. Mats Benner demonstrates how institutions can best respond to changing social, economic and political dynamics to ensure their efficient operation and continued growth.Drawing on case studies from leading univ

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Robo-Advisor is bringing a paradigm shift in the coming financial markets, changing the way individuals make investments. Based on algorithms and data, robo advisors helps in making informed financial decisions without human interventions. However, the enablers of robo advisors remain a grey area of research. Therefore, the presented study focused on exploring the enablers impacting robo advisor a