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Background: Previous studies have reported an inverse association between educational attainment and different osteoarthritis (OA) outcomes. However, none of the previous studies have accounted for potential confounding by early-life environment and genetics. Thus, we aimed to examine the association between educational attainment and knee and hip OA surgery using twin data. Methods: From the Swed
The fundamental energy cost of irreversible computing is given by the Landauer bound of kTln 2 /bit, where k is the Boltzmann constant and T is the temperature in Kelvin. However, this limit is only achievable for infinite-time processes. We here determine the fundamental energy cost of finite-time parallelizable computing within the framework of nonequilibrium thermodynamics. We apply these resul
Surface crack width is regulated in codes to limit corrosion of reinforcement bars in concrete. However, the influence of surface crack width on corrosion damages is not directly inferable from previous research.In this work, data on corroded cracked concrete specimens in chloride environments was compiled. Detailed information was included, such as crack and pit locations, local corrosion pattern
Background: Injury deaths constitute a major avoidable cause of death affecting life expectancy to a different degree in men and women. This study quantified the contributions of injury deaths to the gender gap in life expectancy (GGLE) and life disparity (GGLD) in nine Eastern Mediterranean Region (EMR) countries. Methods: We retrieved annual data on age-sex specific causes of death from the Worl
A supercritical fluid extraction methodology was used to extract flavoring and bioactive compounds from truffles. Some parameters such as CO2 flow rate (1–3 mg/mL), extraction time (15–90 min) and different trapping food matrices (grape seed oil, gelatin, agar agar and water) were optimized using response surface methodology to enhance extraction and trapping yields. The optimal conditions (2.27 m
Background: Adults with congenital heart disease (ACHD) are a group with an increased risk of thromboembolic complications and arrhythmias. Vitamin K antagonists are the most commonly used thromboprophylaxis therapy in this population. Studies on the efficacy and safety of novel oral anticoagulants (NOAC) are scare in ACHD. A retrospective study on ACHD patients on NOAC treatment registered in the
The chapter investigates the democratic potential of politically and socially oriented civil society organizations (CSOs) to engage citizens and articulate citizens’ interests in the policymaking process in North Macedonia. To do so, the chapter reports on the responses of CSOs to a survey which sought information on the extent to which organizations involve members in organizational activities an
InP quantum dots (QDs) are the most competitive in terms of environmentally friendly QDs. However, the synthesis of InP QDs requires breakthroughs in low-cost and safe phosphorus precursors such as tri(dimethylamino)phosphine [(DMA)3P]. It is found that even if the oxygen is completely avoided, there are still oxidation state defects at the core/shell interface of InP QDs. Herein, the record-break
Right ventricular (RV) volumes are commonly obtained through time-consuming manual delineations of cardiac magnetic resonance (CMR) images. Deep learning-based methods can generate RV delineations, but few studies have assessed their ability to accelerate clinical practice. Therefore, we aimed to develop a clinical pipeline for deep learning-based RV delineations and validate its ability to reduce
Various rational metabolic engineering and random approaches have been applied to introduce and improve xylose utilization and ethanol productivity by Saccharomyces cerevisiae. Among them, the BUD21 gene was identified as an interesting candidate for enhancing xylose consumption as its deletion appeared to be sufficient to improve growth, substrate utilization and ethanol productivity on xylose, e
Diabetes mellitus (DM) incidence have been assessed in connection with air pollution exposure in several studies; however, few have investigated associations with source-specific local emissions. This study aims to estimate the risk of DM incidence associated with source-specific air pollution in a Swedish cohort with relatively low exposure. Individuals in the Västerbotten intervention programme
The end-Triassic Mass Extinction (ETME) is generally regarded as a consequence of the environmental changes associated with the emplacement of the Central Atlantic Magmatic Province (CAMP) and ranks among the ‘big five’ mass extinctions in Earth history. A notable feature of the ETME is a halt in marine carbonate deposition followed by the formation of unusual facies such as carbonate cement fans
Dagens svenska skogsbruk är inte ekologiskt hållbart. Att saluföra det som hållbart är därför – för att tala klarspråk – falsk marknadsföring, skriver forskare.
BACKGROUND: The ability of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) to decrease certain microvascular events has called for the investigation of GLP-1 RAs against diabetic retinopathy (DR), but the evidence is limited. By combining data from observational and Mendelian randomization (MR) studies, we aimed to investigate whether GLP-1 RAs decrease the risk of DR.METHODS: We combined da
Farms can harbor substantial biodiversity, which in turn sustains the supply of ecosystem services. The effectiveness of farm management to enhance biodiversity, however, may be modified by land cover in the surrounding landscape beyond a farmer’s direct control. We examined how landscape pattern and farm management affect the abundance and diversity of native bees visiting highbush blueberry in V
Supporting ecosystem services and conserving biodiversity may be compatible goals, but there is concern that service-focused interventions mostly benefit a few common species. We use a spatially replicated, multiyear experiment in four agricultural settings to test if enhancing habitat adjacent to crops increases wild bee diversity and abundance on and off crops. We found that enhanced field edges
Natural hazards are naturally occurring physical events that can impact human welfare both directly and indirectly, via shocks to ecosystems and the services they provide. Animal-mediated pollination is critical for sustaining agricultural economies and biodiversity, yet stands to lose both from present exposure to natural hazards, and future climate-driven shifts in their distribution, frequency,
Depending on management practices, agricultural lands can either pose substantial barriers to species movement or can support landscape connectivity by linking areas of high-quality habitat. Balancing connectivity and sustainable food production on agricultural lands is critical to conservation in the conterminous United States (CONUS) where agriculture makes up close to half of total land area. H
