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Skin cancer is one of the most common forms of cancer worldwide and its prevalence is increasing. Current assessment of tumor extent relies mainly on histopathology after excision, and repeated surgeries are often required to achieve complete tumor removal. This leads to high medical costs and unnecessary patient discomfort. To reduce the pressure on the healthcare system, there is a strong need f
Recent work by Ghose and Pinotsis (2025) reformulated the classical FitzHugh–Nagumo neuronal model as a Schrödinger-like equation. The aim of this thesis is to investigate whether the proposed equation is able to reproduce the dynamics of the original model. Results presented here show that the reformulation is capable of capturing the conservative component of the neuronal model, but not its full
Parvalbumin (PV) interneurons are specialised inhibitory neurons that help regulate the timing and balance of neural circuits. Generating PV-like interneurons through direct glia-to-neuron reprogramming is therefore relevant for disease modelling and future regenerative strategies, but efficient acquisition of a specific PV-associated fate remains challenging. This thesis builds on a human glia-to
Numerical Weather Prediction (NWP) relies on the accurate and efficient numerical solution of nonlinear conservation laws governing atmospheric flows. However, high order DG methods are known to exhibit instabilities when applied to nonlinear conservation laws. Entropy stable methods improve the robustness of these schemes by imposing an entropy inequality on the solution and ensuring that the res
In this thesis, we study groups of superpolynomial growth, with a particular focus on the first Grigorchuk group. Introduced by Rostislav Grigorchuk in 1980, this group serves as a fundamental example of a finitely generated group of intermediate growth. The main result concerns the superpolynomial growth of the first Grigorchuk group, illustrating its relevance for the conjugacy search problem a
We first motivate fusion systems and provide basic definitions. Then we discuss saturated fusion systems and the equivalence of various definitions found in the literature. We then give the definitions of group (co)homology and introduce (co)induced modules, restriction, conjugation and transfer homomorphisms, Shapiro’s lemma, and prove the Cartan-Eilenberg stable elements theorem. Thereafter, we
The extent of data usage today makes the problem of its smoothing and filtering more relevant than ever. In this thesis, we explore one of the possible approaches to this problem: smoothing splines. When trying to clean noisy data, we want the final result to be both smooth and close to the original data set, thus it is logical to simultaneously minimize both of these values, while controlling the
In this thesis, the possibility of cooling small electronic products using new methods is investigated. By improving a base product, different types of methods for enhanced heat dissipation are evaluated. Initially, a literature study is conducted with the goal of analyzing the market and exploring new technology. The literature study is integrated with interviews to gain a more informed understa
Network Display speakers are used as public address (PA) systems as security devices for effective communication of messages. Lately, one of the industry leading companies within IP network product systems launched their own take on this. This thesis aimed at developing a new display speaker in collaboration with them, focusing on sustainability, user feedback and new features. The project follow
BACKGROUND: Heart rate (HR) control in atrial fibrillation (AF) is commonly guided by resting HR measurements, usually with 12‑lead ECG or in-office pulse palpation.OBJECTIVES: We aimed to assess the reliability of resting HR measurements in AF patients with long-term ambulatory ECG and activity monitoring.METHODS: We included patients who had recorded a full-disclosure ambulatory ECG with a mobil
INTRODUCTION: Sexual violence is highly prevalent in North Kivu, the Democratic Republic of the Congo and access to care for survivors remains challenging. This study aims to analyse characteristics of violence, barriers to care and timely access to care among survivors of sexual violence who accessed care in North Kivu following the increase of violence and displacement 2023-2024. Furthermore, it
BACKGROUND: Previous research has shown that mobile health (mHealth) interventions are effective in reminding older adults with chronic conditions about health care appointments and promoting adherence to medication schedules. However, the evidence is limited by the short duration and poor quality of the interventions.OBJECTIVE: We evaluated the effectiveness of the Support, Monitoring and Reminde
Bakgrund: Antalet människor som är på flykt i världen ökar och att vara på flykt kommer ofta med omfattande förändringar i individernas liv. Att etablera ett nytt socialt liv, anpassa sig till en ny miljö eller att uttrycka emotionella behov kan vara särskilt utmanande. Skapande aktiviteter har en stor potential att främja känslouttryck och erbjuda ett nytt socialt sammanhang där man genom engagemBackground: The number of displaced people is increasing, involving major changes in the lives of individuals. It can be challenging to establish one's social life, adapt to a new environment or express emotional needs. Creative activities hold great potential to promote emotional expression and offer a new social context where individuals can express themselves emotionally and experience a se
It is shown that mean conjunction times calculated from the conjunction tables and calculated from the tables of mean solar and lunar longitudes differ by 14 minutes in Peter Apian's Astronomicum Caesareum. It is also shown that Apian used an extra longitude correction for the geographical longitude correction between Toledo and Ingolstadt for the mean longitude and longitude of argument of the Mo
The electromechanical properties of hafnium zirconium oxide fluorite (Hf0.5Zr0.5O2, HZO) remain largely unexplored despite its widespread use as a ferroelectric in CMOS-compatible devices. Here, we demonstrate that electrostriction-driven phase instability enables a giant pseudo-piezoelectric response in epitaxial HZO thin films. Above a critical field of 24 kilovolts per centimeter, field-induced
We developed a novel apparatus based on a lead-glass calorimeter that can measure the flux of high-energy electrons or photons. Our detector uses the electromagnetic shower leakage from the beam dump, where the particles are disposed of at the beamline's end. A prototype of such a calorimeter was set up at the FLASHForward experiment at DESY. We show that it can measure the electron bunch charge w
Wakefield accelerators driven by linear accelerators (linacs) benefit from linearly ramped bunch current profiles, which can increase energy efficiency and reduce induced correlated energy spread in the accelerated bunch. Linacs often employ chicane bunch compressors and higher-harmonic radio-frequency cavities to tune the bunch current profiles. However, while possible, generating linearly rampedWakefield accelerators driven by linear accelerators (linacs) benefit from linearly ramped bunch current profiles, which can increase energy efficiency and reduce induced correlated energy spread in the accelerated bunch. Linacs often employ chicane bunch compressors and higher-harmonic radio-frequency cavities to tune the bunch current profiles. However, while possible, generating linearly ramped
Energy-transfer efficiency is an important quantity in plasma-wakefield acceleration, especially for applications that demand high average power. Conventionally, the efficiency is measured using an electron spectrometer, an invasive method that provides an energy-transfer efficiency averaged over the full length of the plasma accelerator. Here, we experimentally demonstrate the use of the excess lEnergy-transfer efficiency is an important quantity in plasma-wakefield acceleration, especially for applications that demand high average power. Conventionally, the efficiency is measured using an electron spectrometer, an invasive method that provides an energy-transfer efficiency averaged over the full length of the plasma accelerator. Here, we experimentally demonstrate the use of the excess l
Treatment decisions in lung cancer rely on comprehensive molecular and histological characterization, but the limited amount of tumor tissue available from diagnostic procedures remains a major challenge. In this proof-of-concept study, we investigated whether preserving small bronchoscopic tumor specimens in RNAlater enables integrated molecular and histological profiling. Bronchial forceps biops
