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In this paper the topology optimization problem is solved in a finite strain setting using a polyconvex hyperelastic material. Since finite strains is considered the definition of the stiffness is not unique. In the present contribution, the objective of the optimization is minimization of the end-displacement for a given amount of material. The problem is regularized using the phase-field approac
The localized deformation patterns developed during in-plane compression and folding of paperboard have been studied in this work. X-ray post-mortem images reveal that cellulose fibres have been reoriented along localized bands in both the compression and folding tests. In folding, the paperboard typically fails on the side where the compressive stresses exists and wrinkles are formed. The in-plan
Is there a Nordic approach to international law? I argue that a substantive Nordic approach to international law is absent today, and go on to explore, in an essayistic form, why the question of a Nordic international law would emerge today and how the craving for Nordic identity might be overcome. In a first step, I look into select evidence relating to the use of force, to international recognit
Increased biological understanding of cancer diseases has resulted in a paradigm shift in the medical treatment of cancer. Despite encouraging advances, most cancer types are still incurable and cancer is the second most common cause of death in developed countries.The high price of cancer drugs is a major challenge to equal access and puts heavy strains on public health care payers. After sharp i
Background: There is an intense debate about the cost of cancer and the value of new treatments. However, there is limited data on the cost of cancer in the European Union (EU) and how costs relate to the burden of disease. This paper presents new estimates on the development of the cost of cancer in the EU 1995–2014, with a focus on the major cost components: total health expenditure, cancer drug
In a new report, the Swedish Institute for Health Economics (IHE) compares the cancer situation in EU28 plus Norway and Switzerland. The report builds on a previous comparative study conducted in 2005 and provides a comprehensive view of the development of cancer in Europe over the past two decades. The report shows that the number of people diagnosed with cancer continue to increase in Europe, up
Brain-derived neurotrophic factor (BDNF) is an important protein for neuroplasticity and neurogenesis. In this thesis the role of BDNF, in suicidal behaviour was investigated with focus on possible risk factors for suicidal behaviour such as avoidant focused coping, dysfuntional personality traits like impulsiveness and hyperactivity of the Hypothalamic-Pituitary-Adrenal (HPA) axis. Paper I: The Brain-derived neurotrophic factor (BDNF) is an important protein for neuroplasticity and neurogenesis. In this thesis the role of BDNF, in suicidal behaviour was investigated with focus on possible risk factors for suicidal behaviour such as avoidant focused coping, dysfuntional personality traits like impulsiveness and hyperactivity of the Hypothalamic-Pituitary-Adrenal (HPA) axis.Paper I: The a
Open access is a well-known externality problem in fisheries causing excess capacity and overfishing. Due to global warming, externality problems from CO2 emissions have gained increased interest. With two externality problems, a first-best optimum can be achieved by using two regulatory instruments. However, solving the open-access externality problem also affects CO2 emissions. By using a bio-ecOpen access is a well-known externality problem in fisheries causing excess capacity and overfishing. Due to global warming, externality problems from CO2 emissions have gained increased interest. With two externality problems, a first-best optimum can be achieved by using two regulatory instruments. However, solving the open-access externality problem also affects CO2 emissions. By using a bio-ec
Health care as any other public service is subject to many potentially conflicting objectives and many actors. Over time, the traditional goal of health care systems of distributive justice has been accompanied by other objectives and health care reforms have developed accordingly. One type of reform in countries with publicly funded health care has evolved around replacing monopolistic state prov
Background: Policy implementation in the context of health systems is generally difficult and the Kenyan health sector situation is not an exception. In 2005, a new health sector strategic plan that outlines the vision and the policy direction of the health sector was launched and during the same year the health sector was allocated a substantial budget increment. On basis of these indications of
Background: The choice between different attention-deficit/hyperactivity disorder (ADHD) medications depends on different drug attributes. Economic evaluations of drugs often disregard the utility of other attributes compare with the drugs' efficacy. Aims: The aim of this study was to assess patient's preferences and elicit willingness-to-pay (WTP) for different drug attributes in the treatment of
Reformer som fokuserar på ökad privatisering och konkurrens bland utförare och ökad valfrihet för individer(patienter, elever, brukare)har införts i svensk hälso-och sjukvård, skola och omsorg. Individer ska kunnavälja bland offentliga och privata utförare som finansieras med offentliga medel och som förväntas konkurrera om elever, patienter och brukare på en r
