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A perspective overview is given describing the current development of multiplex mass spectrometry assay technology platforms utilized for high throughput clinical sample analysis. The development of targeted therapies with novel personalized medicine drugs will require new tools for monitoring efficacy and outcome that will rely on both the quantification of disease progression related biomarkers
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This report describes a model for the estimation of the time required to evacuate a building, by dividing the evacuation process into three phases: awareness, behaviour and response, and movement. The times required in each of these phases can be estimated separately and the sum then represents the total evacuation time. The time elapsed from the fire breaking out, to the discovery of the fire, is
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Test application and test design, performed to ensure the production of fault-free chips, are becoming complicated and very expensive, especially in the case of SoCs (System-on-Chip), as the number of possible faults in a chip is increasing dramatically due to the technology development. It is therefore important to take test design into consideration as early as possible in the SoC design-flow in
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Short overview of the theme of death and necropoles in works by Emanuel Swedenborg, Derek Walcott, and Albert Engström
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Monastic Archaeology and Sorø-studies: On Monastic archaeology and its typical researchs themes, a look on the themes at three current research projects in Sweden, on the conditions for new studies into the benedictin and cistercian monastery of Sorø on Zealand and finally seven possible themes or questions to explore in the future at Sorø. (Printing year wrongly as 2012 on the title page of the p
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Classical B lymphocyte activation is dependent on BCR cross-linking in combination with physical interaction with Th cells. Other B cell molecules that contribute to the activation are complement, cytokine, and TLRs recognizing specific pathogen-associated molecular patterns. Moraxella (Branhamella) catarrhalis is a common Gram-negative respiratory pathogen that induces proliferation in human IgD-
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In this article, various ways of understanding names and their significance for identity is discussed. A comparison between announcements in the births columns in two Swedish daily papers from 1965 and 1995 reveals that it is much more common to announce the child’s name today. This can be interpreted in relation to the conception of the vulnerability of the new-born baby, documented in the Folkli
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Purine nucleoside phosphorylase (PNP) is an enzyme active in the purine salvage pathway. PNP deficiency caused by autosomal recessive mutations in the PNP gene leads to severe combined immunodeficiency (SCID) and in two thirds of cases also to neurological effects such as developmental delay, ataxia, and motor impairment.PNP deficiency has a poor outcome, and the only curative treatment is allogen
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Background: Evidence-based guidelines should in most cases be followed also in the treatment of elderly. Older people are often suboptimally treated with the recommended drugs. Objectives: To describe how well general practitioners adhere to current guidelines in the treatment of elderly with cardiovascular disease and evaluate local education as a tool for improvement. Method: Data was colle
