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A cDNA encoding the mature human cysteine proteinase inhibitor cystatin C was fused to the coding sequence for the Escherichia coli outer membrane protein A signal peptide, and the recombinant gene was expressed in E. coli under the control of the λ PR promoter, an optimized Shine-Dalgarno sequence and the λ cI 857 repressor. When induced at 42°C, such cells expressed large amounts of recombinant
Consider a stationary normal process ξ(t) with mean zero and the covariance function r(t). Properties of the sample functions in the neighborhood of zeros, upcrossings of very high levels, etc. have been studied by, among others, Kac and Slepian, 1959 [4] and Slepian, 1962 [11]. In this paper we shall study the sample functions near local maxima of height u, especially as u → -∞, and mainly use si
1. Task-dependent modulation of cutaneous input to climbing fibres projecting to the C1, C2 and C3 zones in the cerebellar paravermal lobule V was investigated in awake cats during performance of a reaching task. 2. Climbing fibre responses resulting from low intensity (non-noxious) electrical stimulation of the ipsilateral superficial radial nerve were recorded as extracellular field potentials i
Generation of clusters of free eosinophil granules (Cfegs), through lysis of eosinophils, has recently been proposed as a major paradigm for ultimate activation of airway mucosal eosinophils. In the present study involving patients with seasonal allergic rhinitis, we have investigated whether generation of Cfegs in the nasal mucosa is a feature of allergic rhinitis. Nasal mucosal biopsies were obt
X-ray absorption spectroscopy (XAS) and scanning tunneling microscopy (STM) have been used to study the absorption of monolayers of the pyridinecarboxylic acid monomers (isonicotinic acid, nicotinic acid, and picolinic acid) and benzoic acid on a rutile TiO2(1 1 0) surface. We find that the pyridine and phenyl rings are oriented with their planes largely perpendicular to the surface. The azimuthal
Ställd inför det religiöst motiverade dödsdomen mot en välkänd författare har opinionen i väst stirrat sig blind på en enda aspekt av "Rushdie-affären": den hotade tryckfriheten. Denna artikel analyserar andra sidor av konflikten och söker dess rötter i problem som uppkommer i ett multikulturellt samhälle – problem som även finns i Sverige.
The quantitative information in SPECT images is distorted by photon attenuation and contribution of photons scattered in the object. It is, therefore, important to know the distribution of different attenuating tissues in order to be able to perform a proper attenuation correction. A correction method, based on correcting one pixel at a time by using density maps and build-up functions, has been d
Background: Cell death induced by intracellutar glutathione depletion has been reported to be dependent on the presence of trace amounts of extracellular copper ions. Since little is known about the relationship between glutathione depletion and copper homeostasis, we have in the present study further investigated the role of low amounts of copper ions in glutathione depletion. Methods: Glutathion
Textual criticism-comparison of two different transcripts (one from the Cultural Revolution, the other in an official post-CR source) of CCP General Secretary Deng Xiaoping's speech at 1962 conference in Beijing.
The severity of hand-arm vibration syndrome (HAVS) is usually graded according to the Stockholm workshop scales. Although the Stockholm workshop scales are regarded the gold standard for assessing the severity of HAVS, they are based primarily on subjective symptoms. The aim of the present study was to explore the agreement between Stockholm workshop scales and the outcome from ten well-defined cl
Human polyclonal and monoclonal antibodies against pathogens and toxins are potentially useful in the treatment of various diseases. A number of human monoclonal antibodies with protective capacity in vitro have been established by conventional hybridoma technology. However, with the development of phage-display technology, the possibility of specifically tailoring antigen-binding properties has i
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Humanities for medical students? A qualitative study of a medical humanities curriculum in a medical school program Caroline Wachtler, Susanne Lundin and Margareta Troein Lund University, Department of Clinical Sciences, General Practice/Family Medicine, Malmö University Hospital, SE 20502 Malmö, Sweden 2Lund University, Department of Ethnology, Finngatan 10, SE 223 62 Lund, Sweden BMC Medical Ed
This dissertation deals with the modern predicament of the Rabha or Kocha people, their survival in the forest and their quest for identity. Rabhas are one of India's indigenous or tribal people, and they live in the jungle tracts where the Himalayan mountains meet the plains of Bengal. When the area came under British rule and was converted into tea gardens and reserved forests Rabhas were forced
1 The present study addressed the role of neuropeptide (NPY) Y-2 receptors in neurogenic contraction of mesenteric resistance arteries from female spontaneously hypertensive rats (SHR). Arteries were suspended in microvascular myographs, electrical field stimulation (EFS) was performed, and protein evaluated by Western blotting and immunohistochemistry. 2 In vasopressin-activated endothelium-intac
The scaled opposite spin second-order Moller-Plesset (SOS-MP2) energy expression is reformulated using Cholesky decomposition of the amplitude matrix. The resulting algorithm requires an auxiliary basis or Cholesky representation of the two-electron integrals and shows fourth-order scaling with system size. Based on an analysis of operation counts, we estimate that the present approach is computat
