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Clinical mental health researchers may understandably struggle with how to incorporate biological assessments in clinical research. The options are numerous and are described in a vast and complex body of literature. Here we provide guidelines to assist mental health researchers seeking to include biological measures in their studies. Apart from a focus on behavioral outcomes as measured via inter
The design of supramolecular hydrogels comprising aligned domains is important for the fabrication of biomimetic materials and applications in optoelectronics. One way to access such materials is by the self-assembly of small molecules into long fibres, which can be aligned using an external stimulus. Out-of-equilibrium supramolecular gels can also be designed, where pre-programmed changes of stat
Cell death plays a pivotal role in many physiological processes, such as cell homeostasis, embryonic development, immune defence and in the pathophysiology of numerous diseases, such as cancer, infections and degenerative diseases. However, the lack of a comprehensive and up-to-date resource on cell death regulators poses a significant challenge to researchers in the field. Existing databases are of
Archived radar data has various applications, though it is often underutilised. Nevertheless, this information has the possibility to aid in the development of accurate and relevant climate adaptation tools, inform climate-resilient urban development strategies, and numerous other personal and societal applications. Our work in the RadClim Baltic Sea Region (BSR) project established the potential
Many forms of bioimage analysis involve the detection of objects and their outlines. In the context of microscopy-based high-throughput drug and genomic screening and even in smaller scale microscopy experiments, the objects that most often need to be detected are cells. In order to develop and benchmark algorithms and neural networks that can perform this task, high-quality datasets with annotat
AbstractObjective: The objective is to provide a detailed protocol for a scoping review aimed at mapping and summarizing studies of word definition (WD) skills in children, in clinical and non-clinical populations. More specifically, the aim is to map which factors have been studied as associated with WD skills. Furthermore, the scoping review will summarize the methodological characteristics of t
INTRODUCTION: Neuroanatomical normative modeling captures individual variability in Alzheimer's disease (AD). Here we used normative modeling to track individuals’ disease progression in people with mild cognitive impairment (MCI) and patients with AD. METHODS: Cortical and subcortical normative models were generated using healthy controls (n ≈ 58k). These models were used to calculate regional z
The scattering formulation of characteristic mode decomposition is utilized to extend modal analysis to lossless scatterers breaking time-reversal symmetry. This enables characteristic modes analysis on devices containing gyrotropic or moving media. The resulting nonreciprocity introduces features not observed in reciprocal scenarios, such as asymmetric phase progression in characteristic far fiel
Abstract—In numerous image-based studies, such as cell studies,a plethora of information is embedded in cell objects, whichmust first be accurately extracted before it can be utilized forfurther downstream analysis and linked to biological processesexplored in the original experiment. One such technique forthis purpose is instance segmentation. In our study, whichcell death and associated pathways
The evolution of whole-body endothermy occurred independently in dinosaurs and mammals and was associated with some of the most significant neurocognitive shifts in life's history. These included a 20-fold increase in neurons and the evolution of new brain structures, supporting similar functions in both lineages. We propose the endothermic brain hypothesis, which holds that elaborations in endoth
Positioned within a perceptual approach to European Union (EU) foreign policy, this article explores tensions relating to the resilience of the EU's normative identity, focusing on factors and explanations external to the EU. We engage with EU perceptions amongst external partners theorized as active agents/potential contributors to contestation processes. We focus on the perceived role of the EU
