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This paper introduces the pole ratio metric and presents a sphere-based view of symmetric positive-definite matrix rotations on the Riemannian manifold of symmetric positive-definite matrices equipped with the affine-invariant Riemannian metric. The pole ratio quantifies whether data from different users lie on this Riemannian manifold in a way that enables effective transfer learning. The sphere-
We describe two Hilbert transform-based methods for augmenting covariance matrices from multivariate signals. The two methods are shown to be isometric under the Riemannian affine-invariant metric on the manifold of symmetric/Hermitian positive definite matrices. The augmented representations distinguish cases that standard covariances clearly cannot and, when paired with a Riemannian minimum dist
Background Obstructive sleep apnea (OSA) frequently coexists with coronary artery disease (CAD) and may contribute to heart failure with preserved ejection fraction (HFpEF). Whether HFpEF-like features are reversible with continuous positive airway pressure (CPAP) therapy remains uncertain. Methods A total of 177 revascularized CAD patients with nonsleepy OSA (Epworth Sleepiness Scale score <10; a
Structural adjustment programs (SAPs) and their developmentalimpacts have been extensively studied. Literatures on neo-colonialism and unequal exchange suggest that SAPs representeda continuation or resumption of extractive colonial strategies,promoting the transfer of physical resources and value from post-colonial countries to developed countries. However, there hasbeen little systematic analysi
CD8 + T-cell presence and distribution in oropharyngeal cancer (OPC) reflects specific immune phenotypes and are linked to prognosis. Image processing methods such as convolutional neural networks (CNN) may enhance treatment decisions. From standard computed tomography (CT) images, this study evaluates radiomics in combination with machine learning models and CNN for prediction of spatially resolv
Elevated troponin I (TnI) has been reported in patients with chronic obstructive pulmonary disease (COPD) without cardiovascular disease (CVD), suggesting non-ischaemic mechanisms. We assessed this association in a population-based cohort of 22 526 individuals without known CVD or significant coronary artery calcification. TnI showed no association with COPD (adjusted OR 0.87, 95% CI 0.60 to 1.26;
The development of wide bandgap perovskite solar cells (WBG PSCs) holds significant promise for advancing tandem solar cells. However, the intrinsic rapid crystallization kinetics severely impedes the vertical-oriented growth and homogeneous film formation of perovskite crystals, leading to high defect density and compromised device performance. This work proposes an innovative molecular interfaci
Localizing users and mapping the environment using radio signals is a key task in emerging applications such as reliable low-latency communications, location-aware security, and safety-critical navigation. Recently introduced multipath-based simultaneous localization and mapping (SLAM) methods can jointly localize a mobile agent and map reflective surfaces in radio frequency (RF) environments. Mos
This study extends conventional life cycle assessment (LCA), which typically assumes an incident-free service life, to explicitly incorporate fire events and fire protection systems, enabling systematic quantification of their environmental consequences and mitigation effects in timber buildings. A proof-of-concept application was conducted for a timber-based residential compartment under four rep
This study presents a comprehensive 25-year chronology of air pollution and climatic variable disparity across seven SAARC nations—Afghanistan, Bangladesh, Bhutan, India, Nepal, Pakistan, and Sri Lanka—emphasizing the region’s developing burdens of fine PM2.5 and SO2 from 2000 to 2024. MODIS and MERRA-2 data are used for a regional-scale analysis of seasonal, annual, and inter-annual variations in
Aims: To investigate differences between respondents’ self-reported registration with public and private primary healthcare (PHC) providers according to self-reported illness burden in the early phase of the free choice reform. Methods: The Public Health Survey undertaken in Scania, southernmost Sweden, in 2012 was a population-based study of a stratified random sample of 18–80-year olds that elic
Background: – When decision makers use evidence from a randomized trial to inform population-level decisions, the target population they envision rarely aligns with the population of individuals who enrolled in the trial. Here, we extend inferences from the VALIDATE-SWEDEHEART randomized trial (hereafter, the index trial), which compared the effects of bivalirudin and heparin during percutaneous c
Tetralogy of Fallot (TOF) patients are at risk for long-term adverse events. Electrocardiogram (ECG) abnormalities may reflect ventricular maladaptation and predict complications. We investigated whether ECG changes correlated with cardiac magnetic resonance imaging (CMR) measures of right ventricular (RV) function and their prevalence in less mature myocardium (prematurity or early repair). This
Here, density functional theory calculations are used to evaluate Ti4C3 and Ti4N3 MXenes as sodium ion-battery (SIB) anodes. Both MXenes offer multiple energetically favorable Na adsorption sites with strong binding, supporting uniform Na accommodation and mitigating Na clustering. The Na adsorption increases the electronic density near the Fermi level that enhances metallic conductivity for effic
Adult patients with inherited metabolic diseases are often overlooked. Limited data on this population hinder adequate planning of their clinical and social care. In this retrospective, observational, cross-sectional service evaluation study, we reviewed the electronic medical records of adult patients with inherited neurometabolic diseases (NIMD) managed at Skåne University Hospital between 2020
Is high fertility related to shorter lifespan? Evolutionary theories predict negative physiological effects of fertility on women’s later-life survival. However, kin and especially one’s own children may contribute positively to women’s survival in old age. Family members may transfer resources and provide caretaking assistance as women age and be a source of social support that contributes to hea
Since 2016, the Alzheimer's Association and the Fondation Alzheimer have hosted Global Alzheimer's Leadership Series (GoALS) global think tanks, with world-leading experts for innovative discussions to advance Alzheimer's disease (AD) research and care. The second GoALS think tank, held in June 2024 in Paris, focused on the relationship between biological changes and clinical manifestations of AD
