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Background: Win statistics offer an alternative approach to clinical trials that use survival analysis to analyze composite endpoints. Our objective was to re-analyze data from previously published registry-based randomized controlled trials that produced hazard ratios using win statistics to evaluate the correspondence between them. Good correspondence was defined as both results being positive,

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Brott och straff är idag en av de viktigaste valfrågorna för många väljare. Under de senaste mandatperioderna har stora förändringar av straffsystemet genomförts och regeringspartierna pratar om ett paradigmskifte i kriminalpolitiken. Vad är det egentligen som förändras? Vilket är det gamla paradigmet som nu ska bytas ut? Var brottsbalken en kompromisslösning som i själva verket gjorde alla missnö

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Polycyclic aromatic hydrocarbons (PAHs) of molecular mass (MM) 302 Da comprise numerous structural isomers that are of high concern for human health. Because of their multiplicity, low abundance in the environment, and limited availability of authentic standards, their occurrence, composition, and environmental health risk remain not well characterized. Here we extend the characterization of MM 30

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Ecological constraints and changing societal values require businesses to reconsider innovation opportunities. Sufficiency constitutes an emerging sustainability strategy for businesses that focuses on the absolute reduction of inputs and consumption levels to restrict resource use. This particularly challenges aspects of value generation, strategic orientation, and consumer focus in the context o

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Formulating Research Problems addresses one of the most critical yet often overlooked aspects of research: how to define and frame the problem at the heart of a study. While most research methods texts devote only a few pages to this question, Johan Alvehus offers a dedicated, accessible, and practical guide that helps students move beyond vague topics toward the development of clear, rigorous, an

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Wetlands are often constructed to counteract eutrophication or brownification of downstream waters, although our understanding of their differences in efficiency and effects is still scarce. Therefore, we here used the upper and lower 95% confidence limits of the average retention capacity of 11 wetlands to represent efficient and inefficient wetlands, respectively. We then modelled future scenari

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A random planar quadrangulation process is introduced as an approximation for certain cellular automata in terms of random growth of lines, called rays, from a given set of points. This model turns out to be a particular (rectangular) case of the well-known Gilbert tessellation, which originally models the growth of needle-shaped crystals from the initial random points with a Poisson distribution

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Retrospective, propensity-score-adjusted (PSA) studies have indicated to practitioners in the field that contrast-induced acute kidney injury (AKI) after contrast-enhanced CT (CECT) is of minor importance or even non-existent. This has led to controversies between clinicians demanding CECT not to miss any diagnoses and radiologists reluctant or even refusing CECT in risky patients. A critical revi

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Process-based biosphere models, which formulate biophysical ecosystem processes, provide a mechanistic framework for understanding terrestrial carbon dynamics. In contrast, data-driven approaches, e.g., upscaling eddy covariance (EC) fluxes using satellite observations and machine learning, offer empirical estimates. These complementary methods often diverge significantly, particularly in estimati

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Solar drying is an effective method for food preservation; however, conventional solar dryers often suffer from limited heat transfer and non-uniform airflow, which increases drying time and reduces product quality. These limitations are largely associated with the use of flat absorbers and heat exchangers that restrict turbulence development and weaken thermal performance. To address this issue,

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Purpose: The study aimed to describe patients’ experiences of physical, psychological, social, and existential symptoms and challenges during the first year after allogeneic haematopoietic cell transplantation (allo-HCT). Methods: Quantitative and qualitative data were collected and analysed with descriptive methods as part of a large retrospective cross-sectional online survey of patients who und

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Background: Quantitative fecal immunochemical test (FIT) is widely used for colorectal cancer (CRC) screening, with substantial variation in positivity thresholds across countries. This study examines how these thresholds affect FIT's diagnostic performance for detecting CRC and advanced precancerous lesions (APCL). Methods: We analyzed data from a single round screening of 7398 men and women aged