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Smoking is a risk factor for developing chronic obstructive pulmonary disease (COPD), but there are no good indicators for early identification of subjects who will develop symptomatic COPD. The aim of this study was to investigate inflammatory mechanisms related to changes in lung function and emphysematous changes on high resolution computed tomography (HRCT) in 'healthy' smokers. Subjects were
The need to estimate indoor temperatures, heating or cooling load and energy requirements for buildings arises in many stages of a buildings life cycle, e.g. at the early layout stage, during the design of a building and for energy retrofitting planning. Other purposes are to meat the authorities requirements given in building codes. All these situations require good calculation methods. The main
In a Swedish brass band a program for change was pursued which aimed to improve the artistic level of playing of the ensemble without replacing less competent members. At the time for the study the band comprised 34 members, four of whom were female. The research question was: How does community and group coherence interact with the goal to improve the musical standard in an amateur brass band? T
The adsorption of CO and the reaction of CO with pre-adsorbed oxygen at room temperature has been studied on the (2 x 1)O-Rh(1 1 1) surface and on vanadium oxide-Rh(1 1 1) "inverse model catalyst" surfaces using scanning tunnelling microscopy (STM) and core-level photoemission with synchrotron radiation. Two types of structurally well-defined model catalyst V3O9-Rh(1 1 1) surfaces have been prepar
Recension av Olli Vehviläinen & Attila Pók (eds), Hungary and Finland in the 20th Century.
PURPOSE: To elucidate the role of leucine-rich proteoglycans lumican and fibromodulin in the sclera. METHODS: Lumican- and fibromodulin-null heterozygous mice were intercrossed to obtain wild-type (Lum(+/+)Fmod(+/+)), lumican-null (Lum(-/-)Fmod(+/+)), fibromodulin-null (Lum(+/+)Fmod(-/-)), and double-null (Lum(-/-)Fmod(-/-)) littermates. Axial length was measured on enucleated whole eyes, and ocul
A biogeochemical model of vegetation using observed climate data predicts the high northern latitude greening trend over the past two decades observed by satellites and a marked setback in this trend after the Mount Pinatubo, volcano eruption in 1991. The observed trend toward earlier spring budburst and increased maximum leaf area is produced by the model as a consequence of biogeochemical vegeta
OBJECT: Immortalized neural progenitor cells derived from embryonic rat hippocampus (HiB5), were transduced ex vivo with the gene for mouse nerve growth factor (NGF) to secrete NGF (NGF-HiB5) at 2 ng/hr/10(5) cells in culture. METHODS: Fifty-nine male Wistar rats weighing 300 to 370 g each were anesthetized with 60 mg/kg sodium pentobarbital and subjected to lateral fluid-percussion brain injury o
Soft tissue sarcomas (STS) represent a group of rare and heterogenous tumors that optimally should be diagnosed and treated within multidisciplinary teams. This thesis has studied various aspects ? pathological, genetical, and clinical ? of STS. In study I, we demonstrated that 20% of the patients in a population-based series of 818 STS developed second primary malignancies. An increased risk of
Lack of human exposure data is frequently reported as a critical gap in risk assessments of environmental pollutants, especially regarding "new" pollutants. The objectives of this study were to assess serum levels of the persistent 2,2',4,4',5,5'-hexachlorobiphenyl (CB-153), hydroxylated polychlorinated biphenyl metabolites (OH-PCBs), polybrominated diphenyl ethers (PBDEs), and hexabromocyclododec
Wood is a material with mechanical properties that vary markedly, both within a tree and among trees. Moisture changes lead to shrinkage or swelling and modify the mechanical properties. In the present study both experimental and numerical work concerning the stiffness and the hygroexpansion properties of wood and of fibres and variations in them is presented. The experimental work involves both
Popular Abstract in Swedish Huvudtanken i svensk välfärdspolitik är att genom generella åtgärder skapa ett samhälle tillgängligt för alla medborgare. Det är därför viktigt att undvika segregering och särlösningar och i stället höja normalverksamhetens standard. Fritidshemmets mål och uppgifter är desamma för alla barn och kvaliteten i verksamheten ska vara så hög att alla barns behov tillgodoses. The main idea behind the Swedish welfare state is to create a society accessible to all citizens by using to general measures. It is, therefore, important to avoid segregation and special solutions, and instead increase the standard of normal activities. The objectives and tasks of day centres for school-age children are the same for all children and the quality of the operations should be of a st