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Förbättring av Krämer för Fotodynamisk Behandling av Hudcancer Fotodynamisk terapi (PDT) är en modern och relativt skonsam behandlingsmetod som används vid vissa typer av hudcancer och förstadier till hudcancer. I stället för att operera bort vävnad används ett ljuskänsligt läkemedel som appliceras på huden. När det behandlade området belyses med ljus av en specifik våglängd reagerar läkemedlet mePhotodynamic therapy (PDT) is an established treatment for actinic keratosis and selected non-melanoma skin cancers. Still, its broader use is limited by pain, skin irritation, and formulation constraints associated with high photosensitiser concentrations. This study aimed to develop and evaluate a Crystalip®-based topical PDT formulation that enables two-step manufacturing, delivers methyl-amino

Hur processparametrar kontrollerar partikelstorlek vid mikronisering Mediciner avsedda att inhaleras behöver bestå av väldigt små partiklar för att de effek-ivt ska kunna nå och absorberas av lungorna. Produktion av dessa partiklar kan vara komplex och små ändringar i processparametrar kan leda till stora ändringar i hur effektivt medicinen levereras till lungorna. Detta projekt undersöker en ekvMicronization is a key process in the pharmaceutical industry, particularly in the production of inhalable particles which have to be in the size range of 1-5 µm. Particle size reduction in a spiral jet mill is a complex process which has been investigated theoretically and empirically resulting in complex equations. In this project a simple equation for describing micronization energy (Eµ) and a

We study the effect of more informative feedback on student performance. Using data on the population of Swedish school children, we exploit a reform to the grading system in compulsory school which in 2011 introduced a more granular grading scale and thus provided students with more informative feedback on their academic performance. Exploiting a difference-in-discontinuity research design, we fi

Socioeconomic differences in mortality are among the most pervasive facts of contemporary societies. While the mortality gradient by income is well-established for the period after 1970, knowledge about the origins of the gradient is still rudimentary. We analyze the association between income and cause-specific adult mortality during the period 1905-2014 in an area of southern Sweden using compet

Miljömålsberedningens (MMB) betänkande kommer vid en viktig tid, när tiden blir alltmer knapp för att sträva efter beslutade nationella och internationella mål om klimat och biologisk mångfald. De närmaste åren är på många sätt kritiska för att dels begränsa klimatpåverkan, dels värna om natur och biologisk mångfald i linje med vetenskapen och beslutade ambitionsnivåer. Det är mycket viktigt med å

Peatlands store a substantial amount of carbon in the terrestrial ecosystem. They are both long-term sinks of organic carbon and a major natural source of atmospheric methane. The accumulation of carbon is a result of net primary production surpassing decomposition rates over millennia, whereas methane production is intricately linked to the anaerobic decomposition of carbon mass. Warming-induced

Early-life adversity negatively affects morbidity and survival in late life, but knowledge is limited about effects on women’s reproduction and reproductive health. To deepen our understanding of the full effects of disease exposure in early life, including long-term consequences, we study women’s reproductive outcomes and their offspring’s health. Using the Scanian Economic Demographic Database a

Bakgrund: Patienter med avancerad gastrointestinal (GI) cancer har en hög symtombörda, vilket ofta medför behov av akutsjukvård. Integration av tidig, hem-baserad specialiserad palliativ vård (SPV) tillsammans med tumörspecifik behandling kan påverka behov av akut sjukvård.Metoder: Vid initiering av palliativ kemoterapi randomiserades patienter med avancerad GI-cancer till tidig hem-baserad SPV inBackgroundPatients with advanced gastrointestinal (GI) cancer experience a high symptom burden which frequently necessitates emergency care. Integration of early home-based specialised palliative care (SPC) with tumour-specific treatments may impact emergency healthcare use.MethodsAt the initiation of palliative chemotherapy, patients with advanced GI cancer were randomised to early home-based SPC

This article examines the ways in which parenting practices of refugee parents are the object of concern for the Danish welfare state. Emphasis is placed on how interventions of daycare institutions and other welfare professionals have been experienced by refugee families who live in a context of radical uncertainty since they hold temporary residence permits in Denmark. Based on ethnographic fiel

This article explores the transformative experience of estrangement by a Kurdish Iranian refugee named Hiwa in exile in Denmark. Through a person-centered approach, I focus on what was at stake for stateless people, such as Hiwa, at a time when right-wing populist asylum politics made achieving permanent citizenship an uphill battle and leaving Denmark impossible due to the Dublin Regulation. Draw