Characterisation of Viral Membrane Assembly Proteins A6 and A11 of Vaccinia Virus
Poxviruses are large, double-stranded DNA viruses that replicate directly in the cytoplasm of the host eukaryotic cell. During assembly of viral particle progeny, viral membrane precursors derived from the endoplasmic reticulum, exhibit stabilised open ends inside intermediate structures called crescents. The process of viral membrane biogenesis during poxvirus assembly remains poorly understood.
