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Predicting long-term recurrence of disease in breast cancer (BC) patients remains a significant challenge for patients with early stage disease who are at low to intermediate risk of relapse as determined using current clinical tools. Prognostic assays which utilize bulk transcriptomics ignore the spatial context of the cellular material and are, therefore, of limited value in the development of m
Background: Escherichia coli, the most common bacterium causing urinary tract infections (UTIs), is increasinglyreported as resistant to multiple antibiotics. Swedish surveillance data from hospital and primary health care(PHC) report a 17%–19% prevalence of resistance to ciprofloxacin in E. coli from urine cultures in men over20 years of age. Surveillance data may include nosocomial infections. HBackground: Escherichia coli, the most common bacterium causing urinary tract infections (UTIs), is increasingly reported as resistant to multiple antibiotics. Swedish surveillance data from hospital and primary health care (PHC) report a 17%-19% prevalence of resistance to ciprofloxacin in E. coli from urine cultures in men over 20 years of age. Surveillance data may include nosocomial infections
Peritoneal dialysis (PD) is a cost-effective, home-based kidney replacement therapy that enhances patient autonomy. Nevertheless, the clinical use of PD is limited by chronic fluid overload and excessive glucose absorption, which can lead to complications, such as cardiovascular disease, metabolic disturbances, and deterioration of the peritoneal membrane.The aims of this thesis were to examine gl
In this chapter, we explore the integration of sustainable entrepreneurship education in the context of circular entrepreneurship ecosystems, highlighting the necessity of shifting from traditional profit-centric models towards ones that emphasise sustainability and circular economy principles. We critique current educational practices for overlooking environmental and ethical considerations and a
Forsa conference 2024: Social Work as Emancipatory Practice (17-19 juni)Abstracts to Symposium to Conference theme Social welfare and povertyGeneral abstract [Pollari, Salonen, Leo Sandberg, Söderberg, Linde]Food Assistance in Nordic Welfare states – Questions of Ambiguity and DignityMilja Pollari, Anna Sofia Salonen, Elinn Leo Sandberg, Maria Söderberg, Stig Linde (corresponding author/symposium
In recent years, there has been a wave of opposition to feminism, gender equality, and minority rights in various national and international contexts. While there is a growing number of works that examine anti-gender campaigns, less attention has been devoted to the potential consequences of the anti-gender mobilizations for the internal relations within socially progressive (feminist and LGBTQ+) In recent years, there has been a wave of opposition to feminism, gender equality, and minority rights in various national and international contexts. While there is a growing number of works that examine anti-gender campaigns, less attention has been devoted to the potential consequences of the anti-gender mobilizations for the internal relations within socially progressive (feminist and LGBTQ+)
α-synuclein is a neuronal protein implicated in neurotransmitter release. Its function is thought to critically depend on the dynamic equilibrium between its free and its membrane-bound state. α-synuclein amyloid formation, implicated in Parkinson's disease, is also modulated by lipid membranes. The interplay between these processes remains elusive yet relates to the outstanding question of what d
OBJECTIVES: Analysis of the long-term risks of ischaemic stroke and cerebral bleeding in patients with atrial fibrillation after mitral valve surgery and concomitant Cox-maze IV procedure. METHODS: In total, 397 patients with symptomatic degenerative mitral valve insuffciency and atrial fibrillation, underwent mitral valve surgery and Cox-maze IV in Sweden between 2009 and 2017. In this retrospect
Background: Preterm and low birth weight infants are at an early stage of development, and do not receive adequate maternal circadian signals. They are often cared for over prolonged periods of hospitalisation in neonatal intensive care units (NICU), where environmental circadian stimuli are lacking. Exposure to artificial light–dark cycles may stimulate the development of the circadian system and
In this article, a Stein-type weighted limited information maximum likelihood (LIML) estimator is proposed. It is based on a weighted average of the ordinary least squares (OLS) and LIML estimators, with weights inversely proportional to the Hausman test statistic. The asymptotic distribution of the proposed estimator is derived by means of local-to-exogenous asymptotic theory. In addition, the as
