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Inflammation and subsequent endothelial dysfunction are main players in the vascular component of hypertension, and recent findings points to a key role of Sphingosine- 1-Phosphate and its signaling pathways in its pathophysiology. In neurodegenerative disorders such as Alzheimer’s disease, hypertension is the main modifiable risk factor, but insights regarding S1P receptor modulation in response
The study examines the relation between welfare regimes and notions of solidarity in 2008 and 2016, using quantitative methods. Previous research identifies a strong correlation between type of welfare regime and notions of solidarity. Due to a neoliberal shift in politics and policy-making, the welfare state is changing towards becoming a “workfare” state. This thesis examines if the neoliberal s
Senaste 20 åren har tidsbegränsade anställningar ökat avsevärt. Omstruktureringar inom tillverkningsindustrin, flexiblare organisationer och ständig jakt på ökad konkurrenskraft är en del av faktorerna som bidragit till ökningen. Syftet med denna uppsats är att försöka redogöra hur personer med en tidsbegränsad anställning som är anställda per timme upplever sin tillvaro. Studien har genomförts me
This research project was inspired by the increase in popularity of hillwalking and the problem of the lack of monitoring and maintenance of upland paths which may lead to serious deterioration of those paths. Wicklow Mountains National Park (WMNP), just south of Dublin City in Ireland, has a large network of mostly informal upland paths. A comprehensive baseline survey of many of these paths was
Innebär den ökade e-handeln ett hot mot sysselsättningen inom detaljhandeln och vad är det som orsakar att e-handeln blir allt mer populärt? Frågorna kommer att analyseras i denna uppsats, där den största vikten läggs på den kortsiktiga effekten. Analysen kommer att göras med hjälp av Schumpeters teori om kreativ förstörelse. Det är också denna teorin som lägger grunden till uppsatsens två hypotesHow does the growth of e-commerce affect employment in retail trade, and what is the cause of e-commerce becoming more popular? These questions will be analyzed in this essay, and the main focus will be on the short-term effects of this. Schumpeters theory of creative destruction will be used for this analysis. This theory is also the basis of the hypothesis, the hypothesis being that e-commerce i
När en vårdgivare och en vårdtagare saknar ett gemensamt språk att kommunicera på möjliggörs vården först genom översättning av en tolk. För att utforska svenska psykologers erfarenheter av att arbeta med tolk: vilka problem det ger upphov till, om det går att bedriva behandling samt hur de kontextuella faktorerna ser ut på svenska arbetsplatser, gjordes en enkätundersökning. Enkäten besvarades avWhen a clinician and a patient don’t share a language for communication, an interpreter is needed to enable the communication. To explore the experiences of Swedish psychologists of working with a translator a survey were conducted. The aim of the study were to explore which problems arise from working with an interpreter, the possibility of providing psychological treatment and the workplace rout
During recent years social media has become an important part of the fashion industry. This study is about the social platform Instagram and its effects on fashion. The purpose of this bachelor thesis, Fashion images on Instagram: A netnographic study on the mediatization of fashion and representations of femininity in images on Instagram, is to examine the mediatization of fashion and how feminin
Graphene have attracted attention recently due to its unique properties and opportunities for development of high performance carbon based devices. The intercalation, absorption and reactions processes of small molecules above and below the graphene islands hold the key for new perspectives in catalysis, molecular sensors and other technologies. The present master thesis is focused on the investig
Neonicotinoid insecticides are agonists to nicotinic acetylcholine receptors (nAChRs) in the brains of insects. At sub-lethal doses these chemicals cause behavioral abnormalities in several bee species, reducing overall fitness. nAChRs expressed in the optic lobes of insects bind neonicotinoids, thus may be involved in these behavioral changes. Here we attempted without success to visualize the pr
Oxidativ stress i celler är en bakomliggande faktor till många dödliga sjukdomar. Detta kan kroppen reglera till en viss del med olika proteiner. Ett av proteinerna är Alfa-1-mikroglobulin (A1M) som kan sänka oxidativ stress i kroppen genom att t.ex binda till fria radikaler och bidra till vävnadsreperation. A1M transkriberas tillsammans med ett annat protein, bikunin, som har anti-inflammatoriska
A system for detecting protein-protein interaction using a bacterial two-hybrid approach, a heterologous expression system in Escherichia coli strain based on adenylate cyclase enzyme reconstitution, was invented twenty years ago (Karimova, et al., 1998, PNAS, 95:5752). Before inventing this system, yeast two-hybrid technology was used for screening putative interaction between either two proteins
