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Temperature control is crucial when handling biological particles. In acoustofluidics, temperature regulation is also critical since its fluctuations induce resonance shifts that deteriorates the acoustophoretic performance. In this work, we present a novel simple design that thermally decouples a microfluidic chip from the piezoelectric actuator through a thin copper sheet, allowing precise tempe
Parasites play a fundamental role in explaining variation in population dynamics in wild ecosystems while also acting as a better model-system to study similar or related human infections. Since the late 1800s, malaria parasites have played a crucial role in vector-borne disease research. Many intrinsic and environmental factors can affect the level of infection transmission and prevalence among a
Stora och gamla ekar – framtiden för eklandskapets arter Stora och gamla ekar spelar en viktig roll för den biologiska mångfalden. När en ek åldras utvecklar den olika stamstrukturer, till exempel grov bark, döda grenar, blottad ved och håligheter fyllda med mulm, det vill säga en ansamling av nedbrutet organiskt material. Dessa strukturer skapar livsmiljöer för en stor mängd arter, bland annat iLarge and old trees provide important habitat structures and support a high diversity of species. Habitat continuity and landscape connectivity is crucial for species associated with oaks. Fragmentation, agriculture intensification and changed forest management has caused a reduction of old and large oaks, which threatens the long-term persistence of oak associated species by reducing habitat cont
Alvarens lavar: färgsprakande liv i förändring I slutet av mars och början på april förra året, tillbringade jag två fältveckor på gotländska och öländska alvarmarker. Ofta krypandes, ibland liggandes platt på magen rörde jag mig över stora och små vidder. Somliga dagar bjöd på en värmande vårsol och nyvakna citronfjärilar och andra på bitande iskalla vindar. Men med ögonen fästa på mosaikartade This study investigates the occurrence and distribution of 18 lichen species associated with Nordic alvar and Precambrian limestone habitats on Gotland and Öland, which represent globally unique environments with a generally high biodiversity. During field surveys in the spring of 2025, historically known sites of the chosen lichen species were revisited, where species presence, frequency, and env
Background: Atherosclerotic cardiovascular disease is a chronic inflammatory process initiated when cholesterol-carrying low-density lipoprotein (LDL) is retained in the arterial wall. CD4+ T cells, some of which recognize peptide components of LDL as antigen, are recruited to the forming lesion, resulting in T-cell activation. Although these T cells are thought to be proatherogenic, LDL immunizat
We describe the design and clinical utility of a digital tool aimed to increase the quality of life for chronic pain patients. PainDrainer™ is a drug-free, self-management tool, powered by artificial intelligence that adapts to the self-reported activities of each individual patient, resulting in a truly patient-centric support. The tool was tested in an open label, one-arm pilot study performed i
BACKGROUND AND PURPOSE: Surgical outcomes in patients with flexible adult-acquired flatfoot deformity (AAFD) have not been evaluated in large prospective register studies. Calcaneal osteotomy and hindfoot arthrodesis are commonly used. We aimed to compare the results of these 2 procedures using preoperative and 1-year postoperative patient-reported outcome data from the Swedish Quality Register fo
Plant membrane steroid binding proteins (MSBPs) belong to the membrane-associated progesterone receptors (MAPRs), which is present in all eukaryotic kingdoms. Plant MSBPs have been shown to regulate the function of cytochrome P450 enzymes, bind different steroidal compounds and confer salt tolerance. However, the exact molecular function of plant MSBPs remains elusive. Here, we perform a phylogene
Background: Chronic pain is a highly prevalent disease, leading to high health care costs, impaired productivity, and decreased quality of life. An artificial intelligence (AI)-powered, digital tool for self-management (PaindrainerTM) has been shown to be an effective treatment in chronic pain and may have potential to reduce the burden on costs and quality of life.Objective: The objective of thisBackgroundChronic pain is a highly prevalent disease, leading to high health care costs, impaired productivity, and decreased quality of life. An artificial intelligence (AI)-powered, digital tool for self-management (PaindrainerTM) has been shown to be an effective treatment in chronic pain and may have potential to reduce the burden on costs and quality of life.ObjectiveThe objective of this stu
Electric power systems are undergoing significant transformations as more sectors in society are electrified and new electric power generation from solar and wind is added to the grid. The growing share of renewable generation is expected to influence the dynamic behaviour of power systems, creating a need to develop new control strategies for power systems. This thesis investigates robust and opt
Min avhandling är en undersökning av civilsamhälleliga aktörers vardagliga erfarenheter av hur väpnad konflikt, utvinningsindustri och motstånd har format det colombianska Andinoamazonia under landets pågående fredsbyggande process. Trots ett tjugotal fredsavtal och undertecknandet av ett övergripande avtal 2016 har Colombias långvariga väpnade konflikt inte upphört. Det colombianska AndinoamazoniMy thesis is an inquiry into the daily experiences of civil society actors in relation to how armed conflict, extractivism, and resistance shaped the Colombian Andinoamazonia during the country’s current peacebuilding cycle. Despite two dozen peace agreements, and the signing of a comprehensive agreement in 2016, Colombia’s protracted armed conflict did not end. The Colombian Andinoamazonia, a bio
Klibbiga grenar Föreställ dig, en stilla promenad i lätt vårregn. Känn doften av fuktig jord. Jorddoften kommer från jordlevande bakterierna som kallas Streptomyceter. Då dessa bakterier utgör en av våra viktigaste källor till antibiotika är de särskilt intressanta att studera. Men hur växer de egentligen? I stället för att föröka sig via celldelning bildar dessa bakterier stora nätverk, likt rötStreptomycetes grow as filamentous cells called hyphae. These cells elongate using a polar method of growth where the cell wall synthesis is restricted to the hyphal tips. It has been proved that the protein DivIVA directs the cell wall assembly to the poles and initiate branch formation along the lateral cell wall. Observations of DivIVA shows that it is regulated by AfsK, a Ser/Thr protein kinas
Trygghet i offentliga trafikmiljöer är en central aspekt av hållbar och inkluderande stadsplanering. Studien undersöker hur kvinnor och män upplever trygghet vid Helsingborg C, en plats som kännetecknas av hög genomströmning av människor, varierande ljusförhållanden och återkommande upplevelser av otrygghet. Syftet är att öka förståelsen för hur kön, tid på dygnet och miljömässiga faktorer samverkThis bachelor’s thesis explores how safety is experienced at Helsingborg Central Station (Helsingborg C) from a gender perspective. The aim is to analyse how women and men perceive safety in and around the station area and how these perceptions are influenced by both physical and social environmental factors. The study also seeks to identify which elements contribute most strongly to feelings of i
BACKGROUND AND OBJECTIVE: Although the effects of 5-α-reductase inhibitors (5-ARIs) on prostate-specific antigen (PSA) have been well-studied, the effects on other kallikrein markers have not been firmly established. Accordingly, a statistical model based on blood measurements of four kallikreins-known commercially as the "4Kscore"-cannot be used for men taking 5-ARIs. We investigated how finaster
