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Development and function of specified thymic iNKT1 cells critically depend on an Ets1-Tbet transcription factor axis

Invariant natural killer T 1 (iNKT1) cells are prototypic interferon γ-producing, innate-like T lymphocytes that play crucial roles in protection against pathogen infection and cancer. In the thymus, where these cells develop, iNKT cells contribute to the recruitment of antigen-presenting cells and promote T cell tolerance. Although the transcriptional programs guiding iNKT cell specification are

Exploring self-care practices, experiences, and interventions among adolescents and young adults with type 1 diabetes in Sub-Saharan Africa : a scoping review protocol

This scoping review aims to systematically explore the extent, nature, and gaps in the existing literature on self-care practices among adolescents and young adults aged 10–24 years living with type 1 diabetes mellitus (T1D) in Sub-Saharan Africa. The review will examine self-care knowledge, attitudes, practices, perceived barriers and facilitators, and interventions developed to support self-care

A Novel Approach for Fault Detection and Failure Analysis of CMOS Copper Metal Stacks

For the Inner Tracking System 3 (ITS3) upgrade, the ALICE experiment at CERN requires monolithic active pixel sensors of dimensions up to 97 mm×266 mm, occupying a large fraction of a 300 mm wafer. To manufacture such a wafer-scale device, larger than the single design reticle size, stitching is employed. The MOnolithic Stitched Sensor (MOSS) is a prototype silicon pixel sensor of 14 mm×259 mm siz

Questioning care : ambiguous relational ethics between a refugee child, her parents and the Danish welfare state

Drawing on ethnographic fieldwork, in this article, I tell the story of a particular Syrian family and their encounter with a day-care institution in Denmark – and by extension with the Danish state. In doing so, I highlight how the initially legitimate worries and genuine care of the institution turned into a form of ‘coercive concern’ (Jaffe-Walter 2016) as the family failed to fully meet the re

The impacts of the covidfencing phenomenon in three European cross border regions

This article adopts a temporal and multi-level perspective on thephenomenon of covidfencing, which emerged during the COVID-19 pandemic of the early 2020s and led to widespread ‘re-bordering’ across European cross-border regions. It explores howdifferent regions experienced covidfencing and analyzes theprocesses that produced divergent outcomes, consideringdevelopments at regional, national, and E

Utvärdering och goda exempel

Detta kapitel handlar om ”det goda exemplet” som en lösning på diverse samhällsutmaningar och dess något paradoxala relation till utvärdering. Å ena sidan baseras goda exempel ofta på utvärdering, gärna med hänvisning till evidens och vetenskaplighet. Å andra sidan ser vi dels en stor variation i vad som anses vara ett gott exempel, dels ser vi ganska lite referenser till evidens och vetenskapligh

Gaussian Process Approximation for Differential Equations

This thesis develops a Bayesian framework based on Gaussian processes for inferring parameters of differential operators from data and reconstructing the corresponding solution together with its uncertainty. Such inverse problems are often ill-posed and sensitive to noise, which makes classical deterministic inverse approaches unstable and limits their ability to quantify uncertainty. The setup co

From sparks to nanoparticles: controlling composition at the nanoscale

Nanoparticle properties depend strongly on composition, making precise control essential for applications in catalysis, sensing, and electronics. By combining two or more elements in a single particle, synergistic properties can emerge that are inaccessible to the individual constituents. Realising these benefits, however, requires reliable methods for tuning composition at the nanoscale.This thes

European awakening : Discursive Europeanisation and academic embrace of Europe at Lund University, 1985–1995

This article analyses the Europeanisation of Lund University from the mid-1980s until Sweden joined the European Union in 1995. At Lund University, internationalisation had long been high on the agenda but had not had any clear geographical focus. This was to change in the second half of the 1980s, particularly in 1987–1988, when the new emerging European market in research and higher education co

Indigenous and local knowledge inclusion in forest fauna research : A systematic review in the tropics

Indigenous and Local Knowledge (ILK) is an expression of biocultural diversity and is vital for inclusive and sustainable forest management and epistemic justice. We examine how researchers studying tropical forest fauna engage with ILK and the Indigenous Peoples and Local Communities (IPLC) who are holders of this knowledge. We conducted a systematic review of 62 articles that focus on tropical f

Radiomics-based ultrasOund Model for differentiating Uterine Sarcomas from leiomyomas (ROMUS) : a retrospective pilot Multicenter Italian Trials in Ovarian Cancer (MITO) study

Objective: To develop machine-learning models that incorporate clinical information and radiomics features extracted from ultrasound images to distinguish uterine sarcomas from leiomyomas. Methods: This retrospective, multicenter, pilot case–control study included 200 patients (100 with a uterine sarcoma and 100 with a usual-type leiomyoma, i.e. including no benign leiomyoma variants) who underwen

Proportion of time vocalising as a metric of vocal activity

A fundamental aspect of describing vocal activity is to quantify its overall level. For instance, everyone agrees that animals become more vocal when they are excited or stressed, but what does it mean to be ‘more vocal’? Increased duration of individual calls and their repetition rate are the most commonly reported temporal markers of arousal, but proportion of time [spent] vocalising (PTV) appea

Changes in Long-Term Survival After Stroke Between 2013 and 2020 : A Nationwide Cohort Study from the Swedish Stroke Register

IntroductionChanges in long-term survival after stroke at the population level are incompletely characterized, particularly using recent data and stratified by stroke type.Patients and MethodsThis nationwide, register-based cohort study used data from the Swedish Stroke Register (Riksstroke) and the Swedish Causes of Death Register. Adults (≥18 years) hospitalized with ischemic stroke or intracere