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Characterization of Indigestible Carbohydrates in Various Fractions from Wheat Processing

Fractions rich in indigestible carbohydrates, such as fructan and arabinoxylan, are obtained as by-products when ethanol, starch, and gluten are produced from wheat flour. Today, these fractions are used as animal feed. However, these components may have positive physiological effects in humans. In this study, the content of indigestible carbohydrates in distillers' grains and process streams from

Neurodevelopmental outcomes in children with isolated congenital diaphragmatic hernia : A systematic review and meta-analysis

Background: Congenital diaphragmatic hernia (CDH) reportedly has neurologic consequences in childhood however little is known about the impact in isolated CDH. Aims: Herein we aimed to describe the risk of neurodevelopmental complications in children born with isolated CDH. Materials & Methods: We systematically reviewed literature for reports on the neurological outcome of infants born with i

Three-step conversion of Indulin AT to muconic acid under mild conditions

The conversion of technical lignin into valuable chemicals is important for the complete utilization of lignocellulose. The kraft process dominates the pulp industry, and large amounts of kraft lignin are produced worldwide. However, the complexity of lignin limits its valorization. In this study, a kraft lignin, Indulin AT, was depolymerized under base conditions, and the effects of substrate loa

Comorbidities in multiple myeloma and implications on survival : A population-based study

High proportion of patients with multiple myeloma suffer from comorbidities which may alter clinical management. Therefore, our aims were to evaluate the prevalence of comorbidities and their impact on survival. We included patients diagnosed with multiple myeloma 1990-2013 in Sweden and all diagnoses from each patient from 1985. A total of 13 656 patients with multiple myeloma were included in th

Delayed vascular complication after collagenase injection for Dupuytren disease

Background: Vascular adverse events after collagenase injection for Dupuytren disease are absent in large trials and systematic reviews. The aim of this study is to present a case series of delayed vascular complications after collagenase treatment. Methods: A prospective evaluation of 1181 consecutively treated patients at one orthopedic department identified three patients reporting symptoms of

Family history of type 2 diabetes delays development of type 1 diabetes in TEDDY children with islet autoimmunity

Aims/hypothesis: The aetiology of type 1 diabetes remains elusive. Family history of type 1 diabetes increases the disease risk but the role of other autoimmune diseases or type 2 diabetes in the family are unclear. Here, we aimed to analyse the effect of family history of diabetes and autoimmune diseases on development of islet autoimmunity and progression to type 1 diabetes. Methods: The Environ

P-Wave Morphological Variability Exacerbation Prior to Atrial Fibrillation Episodes

This study analyzes the temporal evolution of the short-term P-wave morphological variability (PWMV) within the one-hour interval immediately preceding the onset of atrial fibrillation (AF) episodes. This PWMV is hypothesized to be an index of vulnerable atrial substrate, allowing to identify instability increases preceding the AF episode onset. We analyzed 32 ambulatory ECG recordings from subjec

Using pile-up collisions as an abundant source of low-energy hadronic physics processes in ATLAS and an extraction of the jet energy resolution

During the 2015–2018 data-taking period, the Large Hadron Collider delivered proton-proton bunch crossings at a centre-of-mass energy of 13 TeV to the ATLAS experiment at a rate of roughly 30 MHz, where each bunch crossing contained an average of 34 independent inelastic proton-proton collisions. The ATLAS trigger system selected roughly 1 kHz of these bunch crossings to be recorded to disk. Offli

Accuracy of q-space related parameters in MRI: Simulations and phantom measurements

The accuracy of q-space measurements was evaluated at a 3.0-T clinical magnetic resonance imaging (MRI) scanner, as compared with a 4.7-T nuclear magnetic resonance (NMR) spectrometer. Measurements were performed using a stimulated-echo pulse-sequence on n-decane as well as on polyethylene glycol (PEG) mixed with different concentrations of water, in order to obtain bi-exponential signal decay cur

Autonomic Neuropathy-a prospective cohort study of symptoms and E/I Ratio in normal glucose tolerance, impaired glucose tolerance, and type 2 diabetes

Background: Autonomic neuropathy in diabetes, in addition to causing a range of symptoms originating from the autonomic nervous system, may increase cardiovascular morbidity. Our aim was to study the progression of autonomic neuropathy, based on symptom score and evaluation of an autonomic test, in persons with normal and impaired glucose tolerance and in patients with type 2 diabetes (T2D). Metho

Preoperative vestibular ablation with gentamicin and vestibular 'prehab' enhance postoperative recovery after surgery for pontine angle tumours - first report

Conclusions. Preoperative gentamicin in combination with vestibular 'prehab' offers a possibility to reduce postoperative malaise and speed up recovery and may be used for patients undergoing such surgery when there is remaining vestibular function. Objectives. Removal of pontine angle tumours in a patient with remaining vestibular function causes symptoms of acute vestibular loss. A simultaneous

ADP Acting on P2Y13 Receptors Is a Negative Feedback Pathway for ATP Release From Human Red Blood Cells.

Red blood cells may regulate tissue circulation and O-2 delivery by releasing the vasodilator ATP in response to hypoxia. When released extracellularly, ATP is rapidly degraded to ADP in the circulation by ectonucleotidases. In this study, we show that ADP acting on P2Y(13) receptors on red blood cells serves as a negative feedback pathway for the inhibition of ATP release. mRNA of the ADP recepto

Seasonal variation in temperature sensitivity of bacterial growth in a temperate soil and lake

Faster bacterial biomass turnover is expected in water compared to soil, which would result in more rapid community adaption to changing environmental conditions, including temperature. Bacterial community adaptation for growth is therefore predicted to have larger seasonal amplitudes in lakes than in soil. To test this prediction, we compared the seasonal variation in temperature adaptation of ba

Rapid short-term poly-beta-hydroxybutyrate production by Thiosphaera pantotropha in the presence of excess acetate

During substrate-limited growth, some strains of Thiosphaera pantotropha nitrify heterotrophically and denitrify aerobically. These processes are thought to be used as NADH overflow mechanisms, resulting from a restricted oxygen respiration capacity. In this study, the behavior of T. pantotropha regarding the NADH overflow in the presence of substantial concentrations of substrate was examined. Co

Phosphoproteins and protein kinase activities intrinsic to inner membranes of potato tuber mitochondria

Inside-out submitochondrial particles (IO-SMP) were isolated and purified from potato (Solanum tuberosum L. cv.) tubers. When these IO-SMP were incubated with [γ32P]ATP more then 20 proteins became labelled as a result of phosphorylation. The 32P incorporation was stimulated by the oxidizing reagent ferricyanide. Except for a 17 kDa protein which was phosphorylated only in the absence of divalent

Aspects of Left Ventricular Morphology Outperform Left Ventricular Mass for Prediction of QRS Duration

Methods: The study population of healthy adult volunteers was divided into a sample for development of a prediction model (n = 63) and a testing sample (n = 30). Magnetic resonance imaging data were used to assess anatomical characteristics of the left ventricle: the angle between papillary muscles (PMA), the length of the left ventricle (LVL) and left ventricular mass (LVM). Twelve-lead electroca

Single-molecule Detection and Mismatch Discrimination of Unlabeled DNA Targets

We report on a single-molecule readout scheme on total internal reflection fluorescence microscopy (TIRFM) demonstrating a detection limit in the low fM regime for short (30-mer) unlabeled DNA strands. Detection of unlabeled DNA targets is accomplished by letting them mediate the binding of suspended fluorescently labeled DNA-modified small unilamellar vesicles (Ø approximately 100 nm) to a DNA-mo

A low-energy electron microscopy and x-ray photo-emission electron microscopy study of Li intercalated into graphene on SiC(0001)

The effects induced by the deposition of Li on 1 and 0 ML graphene grown on SiC(0001) and after subsequent heating were investigated using low-energy electron microscopy (LEEM) and x-ray photo-emission electron microscopy (XPEEM). For 1 ML samples, the collected photoelectron angular distribution patterns showed the presence of single pi-cones at the six equivalent K-points in the Brillouin zone b

Impact of Climate and Predation on Autumn Migration of the Curlew Sandpiper

Using constant-effort catch data, causes of annual variation in the timing of migration of Curlew Sandpipers (Calidris ferruginea) migrating through Ottenby, Sweden, as well as the trend in timing of migration from 1946-2005, was investigated. Variation in the timing of autumn migration of adult and juvenile Curlew Sandpipers was influenced by breeding success connected to predation pressure on th