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The spectrum of diseases causing fever of unknown origin in Turkey : a multicenter study

OBJECTIVE: The purpose of this trial was to determine the spectrum of diseases with fever of unknown origin (FUO) in Turkey.METHODS: A prospective multicenter study of 154 patients with FUO in twelve Turkish tertiary-care hospitals was conducted.RESULTS: The mean age of the patients was 42+/-17 years (range 17-75). Fifty-three (34.4%) had infectious diseases (ID), 47 (30.5%) had non-infectious inf

The outbreak of Ebola virus disease in 2022 : A spotlight on a re-emerging global health menace

Ebola virus disease (EVD) is a rare but highly contagious and lethal disease that occurs predominantly in African countries, with a case-fatality rate of 30–90%. The causative viral pathogens of EVD are within the genus Ebolavirus in the family Filoviridae. The primary route of human-to-human transmission is through direct contact with blood, bodily fluids and secretions from infected individuals.

Perinatal outcomes of cesarean deliveries in Sierra Leone : A prospective multicenter observational study

Objective: To analyze the indications for cesarean deliveries and factors associated with adverse perinatal outcomes in Sierra Leone. Methods: Between October 2016 and May 2017, patients undergoing cesarean delivery performed by medical doctors and associate clinicians in nine hospitals were included in a prospective observational study. Data were collected perioperatively, at discharge, and durin

Secondary Sex Pheromone Components of Choristoneura murinana Hb.(Lepidoptera Tortricidae)

The alkenyl acetates E9-12:Ac, ∆ll-12:Ac and Zll-14:Ac were identified as minor components of the C. murinana female pheromone blend by chemical analyses of volatile pheromone gland constituents and potential pheromone precursors, electrophysiological recordings from single receptor cells, and field trapping tests. Gland washes from virgin females contained these compounds at 3%, 10% and 5%. respe

Influence of user-related parameters on calculated energy use in low-energy school buildings

Literature and experience show that there are large discrepancies between the calculated and measured building energy usages, where user-related parameters are significant factors with regard to energy use in low-energy buildings. Furthermore, the difficulties encountered when quantifying these parameters compound these discrepancies. The main aim of this study was to provide feedback that would h

Protective effects of BDNF and NT-3 but not PDGF against hypoglycemic injury to cultured striatal neurons

Brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and platelet-derived growth factor (PDGF) exert trophic effects on striatal neurons in vitro, which raises the possibility that these growth factors might also counteract neuronal death provoked by various insults. We have found that BDNF and NT-3, but neither PDGF-AA nor -BB, added 24 h before the insult ameliorated hypoglycemic neu

Lactate improves SAPS 3 prognostication

Introduction: Lactate concentration is known to be a strong predictor of mortality, but is not included in any of the major intensive care scorings systems such as the Simplified Acute Physiology Score (SAPS 3). The objective of this study was to investigate the prognostic value of lactate concentration when combined with SAPS 3. Materials and methods: In the period of 2008 to June 2017 the genera

Glycaemic and satiating properties of potato products

Objective: To investigate glycaemic and satiating properties of potato products in healthy subjects using energy-equivalent or carbohydrate-equivalent test meals, respectively. Subjects and setting: Thirteen healthy subjects volunteered for the first study, and 14 for the second. The tests were performed at Applied Nutrition and Food Chemistry, Lund University, Sweden. Experimental design and te

Comparison of thermal manikins of male and female body shapes

During Subzero project there were observed some differences between different manikins. In order to study the differences closer complementary measurements were carried out on 2 manikins representing male and female body shapes. Comparison was carried out based on: • tight versus loose clothing; • serial versus parallel calculation model; • even versus uneven clothing (insulation) distribution; •

Greenhouse gas production in nitrogen removal wetlands

Nitrogen removal wetlands are constructed in agricultural areas as a measure to reduce the amount of non-point source nitrogen that reaches coastal areas. Methane and nitrous oxide, two greenhouse gases, are produced under anaerobic conditions and an increased amount of waterlogged areas will therefore increase the potential emission of these gases. The question has arisen: Are we solving one envi

Doing the Right Thing for the Right Reason: : Why Dynamic or Static Approaches Should be Taken in the Interpretation of Treaties

In the interpretation of treaties, according to Article 31 of the 1969 Vienna Convention, interpreters shall pay primary regard to conventional language and to "relevant rules of international law applicable in the relations between the parties". Applying this provision, it is obvious that interpreters will sometimes face questions of an inter-temporal nature. What law or what language should be b

An automatic method for quantification of myocardium at risk from myocardial perfusion SPECT in patients with acute coronary occlusion.

BACKGROUND: In order to determine myocardial salvage, accurate quantification of myocardium at risk (MaR) is necessary. We present a validated novel automatic segmentation algorithm for quantification of MaR by myocardial perfusion SPECT (MPS) in patients with acute coronary occlusion. METHODS AND RESULTS: Twenty-nine patients with coronary occlusion were injected with a perfusion tracer before re

Influence of Preoperative Chemotherapy on the Intraoperative and Postoperative Course of Liver Resection for Colorectal Cancer Metastases.

BACKGROUND: Liver resection is a possibly curative treatment for colorectal cancer (CRC) liver metastases. Preoperative chemotherapy may make initially irresectable tumors resectable. The aim of this study was to compare perioperative course and short-term mortality after liver resection for CRC metastases between patients who were and were not treated with preoperative chemotherapy. METHODS: Pati

Increased renal arterial resistance predicts the course of renal function in type 2 diabetes with microalbuminuria

Type 2 diabetic patients often die because of end-stage renal failure, but no definitive reliable factor predicting long-term renal outcome has been identified. We tested whether a renal arterial resistance index (R/I) >= 80, using Doppler ultrasound technique, was predictive of worsening renal function. The primary end points of the study were 1) the course of glomerular filtration rate (GFR) and

Prestudy on diffusion and transient condensation of water vapor in cement mortar

The kinetics of sorption of water vapor in mature cement mortar are examined experimentally by the use of a sorption balance (DVS1000). The relative humidity in the sample chamber is obtained by mixing dry and saturated air using flow regulators with very high accuracy. A predefined change of relative humidity in the sample chamber can be obtained in about 30 s. The time needed for equilibration i

Epidermal growth factor receptor status and persistent activation of Akt and p44/42 MAPK pathways correlate with the effect of cetuximab in head and neck and colon cancer cell lines.

OBJECTIVE: The aim of this study was to investigate the effect of epidermal growth factor receptor (EGFR) blockade on cell survival and on downstream signalling pathways using the monoclonal antibody cetuximab. METHODS: We used three colon cancer cell lines, of which one was EGFR-negative, and two head and neck squamous cell carcinoma (HNSCC) lines. EGFR expression and gene copy number were measur

Ethanol inhibits the peak of muscarinic receptor-stimulated formation of inositol 1,4,5-trisphosphate in neuroblastoma SH-SY5Y cells

The effect of ethanol on muscarinic receptor-stimulated formation of inositol 1,4,5-trisphosphate was studied in human neuroblastoma SH-SY5Y cells. Stimulation with carbachol induced a biphasic increase of inositol 1,4,5-triphosphate with an initial peak after 10 sec declining to a plateau phase of elevation above basal levels, which was sustained for at least 5 min in the presence of agonist. The

Kinetics of premixed acetaldehyde plus air flames

Non-stretched laminar burning velocities, SL, of acetaldehyde + air mixtures at initial gas mixture temperatures, T, of 298, 318, 338, 348 and 358 K are reported for the first time. The flames were stabilized on a perforated plate burner at 1 atm using the heat flux method at conditions where the net heat loss from the flame to the burner is zero. Uncertainties of the measurements were analyzed an

The potential role of isothermal calorimetry in studies of the stability of fresh-cut fruits

Attention is drawn to the feasibility of using high sensitivity isothermal heat conduction calorimetry to study metabolic responses of differently processed and stored fresh-cut fruit. The heat production of endogenous (tissue metabolism during 12 h of analysis at 10 degrees C for kiwifruit and strawberry) and exogenous (microbial growth during 18 d of analysis at 10 degrees C for cantaloupe) biol