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Lipid nanopartiklar, förkortat LNP, används bland annat vid cancerbehandling och vaccinutveckling. Deras funktion är att transportera och skydda verksamma ämnen såsom antikroppar, proteiner och peptider. Ett välkänt exempel är coronavaccinet, där LNP transporterar mRNA och skyddar det från att brytas ner i kroppen. Lipid nanopartiklar består av olika lipider: positivt laddade, fosfolipider, kolestOver the past decade an increasing amount of studies has demonstrated that PEGylation not only precipitates reductions in drug delivery efficiency but also triggers the immune system to produce antibodies, specifically anti-PEG antibodies. The objective of my thesis is to explore alternative surfactants that could viably replace PEG within lipid nanoparticles. Specifically, Polysorbate 80 (P80), a

Den svenska bostadsmarknaden präglas av en bostadsbristsituation, en situation som enligt Boverket förvärrats av omvärldshändelser som covid-19 och kriget i Ukraina. Det är i denna kontext intressant att undersöka orsaken och implikationerna av observerade skillnader i belåningsgrad och marknadsvärdestillväxt mellan kommunala bostadsbolag och privata fastighetsbolag. Syftet med arbetet är att unIn Sweden it has for many years been the common understanding that there is a shortage of housing on the housing market, a situation that according to Boverket has been further worsened by recent world events such as the Covid-19 pandemic and the Russian war of aggression against Ukraine. In this context it was interesting to study the cause of and implications of observed differences in the grow

This thesis aims to address the challenges of implementing circular economy (CE) practices in emerging/developing economies by harnessing the resources of multinational corporations (MNCs) to improve waste management situations in these areas of the world. A case study is conducted on a Swedish beverage carton producer operating in Thailand to examine the key challenges and strategies employed by

Syfte. I nuläget används narrativ bedömning begränsat i klinik. Syftet med uppsatsen var att bidra till att öka möjligheten till klinisk användning av Internal State Terms (IST) i språklig bedömning av narrativ förmåga. Syftet var också att bidra till tydliggörande av definitioner för de olika kategorierna av IST. Detta undersöktes genom att studera användningen av IST hos barn i förskoleåldern, sPurpose. The use of narrative assessment in clinical practice is limited. The purpose of this thesis was to contribute to the feasibility of using Internal State Terms (IST) when assessing narrative ability. In addition, we hoped to contribute to clearer definitions of the different categories of IST. Number of IST and types of IST used by preschool children were studied. The hypotheses were that

LSS stadgar rätten till insatser för vissa personer med funktionsnedsättning. Den enskilde ska genom insatserna få möjlighet att kunna leva som andra och tillförsäkras goda levnadsvillkor. En av dessa insatser är personlig assistans som innebär ett personligt utformat stöd för personer med stora och varaktiga funktionshinder. Bedömningen av rätten till insatsen är baserad på tid som fattningen av The Act on Support and Service for Person with Certain Functional Impairments (hereafter LSS) is an entitlement law. Individuals that meet the criteria specified by the act are entitled to measures pursuant to LSS. The measures pursuant to LSS shall guarantee good living conditions and the objective of LSS is to give the individual the opportunity to live like others. One of these measures pursuan

Sekundär användning av e-hälsodata är ett viktigt steg i att direkt och indirekt stärka vården, både inom Sverige och EU. Inom kort förväntas den uppmärksammade EU-förordningen om ett European Health Data Space (EHDS) antas. Genom förordningen kommer ett gemensamt hälsodataområde skapas vilket bland annat möjliggör sekundär användning av uppemot 450 miljoner EU-medborgares e-hälsodata för exempelvSecondary use of e-health data is an important step in directly and indirectly strengthening healthcare, both in Sweden and the EU. The anticipated EU regulation on a European Health Data Space (EHDS) will create a common health data space, allowing for the secondary use of the e-health data of up to 450 million EU citizens for research, innovation and decision-making. This has the potential to re

In today’s fast-paced society, working parents face increasing challenges in providing young children with engaging, developmentally beneficial activities while balancing their responsibilities and limited time. As a result, many parents rely on screens beyond recommended guidelines as a convenient way to occupy their children. However, research shows that excessive screen use is not ideal for chi

Den här studien ämnade att undersöka huruvida olika musikgenrer; blues , klassisk musik och rockmusik, samt utan musik (kontrollgrupp), påverkar prestation i matematik. 52 personer deltog i studien och de blev alla tilldelade en av de fyra musikgenrerna genom en mellangruppsdesign. Studien bestod av två test. Första testet var ett standardiserat matematiktest bestående av 12 frågor (refereras tillThis study aims to investigate how listening to different music genres; blues, classical, and rock, as well as no music (control condition), affects mathematical performance. 52 individuals participated in the study and all were assigned to one out of the four music conditions using a between-subject design. The study includes two tests. The first test was a 12 question standardized mathematics te

I brottmålsförfarandet förordnas ofta sakkunniga. Sakkunniga tillför domstolarna kunskap inom ett visst ämne. Domstolarna ska fastställa bevisvärdet av den sakkunnigas slutsatser, ofta utan egen kunskap inom ämnet. Psykologer är en typ av experter som ofta förordnas som sakkunniga. Slutsatser presenterade av psykologer tenderar att vara särskilt svårbedömda då den psykologiska disciplinen är komplExperts are commonly appointed in criminal cases to provide the court with relevant insight based on specialized knowledge within their area of professional experience. The court must determine the evidential value of the expert’s testimony, despite having little or no knowledge or training in the field of expertise. Conclusions provided to the court by psychologists tend to be particularly proble

This thesis explores the intersection of vernacular knowledge, modern technology and community engaging design to address the challenges posed by flooding and rising water levels in vulnerable areas. Initiated as a conceptual project for a flood resilient neighbourhood, the project evolved into a direct response to the specific needs of the DRCNAI community in Coloong, Valenzuela, Philippines. Thr

Trygg i starten, stark i längden Trygg i starten, stark i längden – Vikten av introduktion för nyexaminerade En rapport från Saco i samarbete med Saco studentråd Trygg i starten, stark i längden Vikten av introduktion för nyexaminerade Hedvig Modin © Hedvig Modin och Karin Fristedt Saco 2025 www.saco.se 1 Innehåll Sammanfattning 2 Nuläge och forskning 3 Starten i arbetslivet 3 Framgångsfaktorer fö

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info Letter bntu in focusg e n d e r RAOUL WALLENBERG INSTITUTE OF HUMAN RIGHTS AND HUMANITARAN LAW AND BELARUSIAN NATIONAL TECHNICAL UNIVERSITY, FACULTY OF MANAGEMENT TECHNOLOGIES AND HUMANITARISATION DO INVITE HEREWITH HIGHER EDUCATIONAL ESTABLISHMENT TEACHERS AND PHD STUDENTS, REPRESENTATIVES OF THE STATE ADMINISTRATION AUTHORITIES AND CIVIL SOCIETY ORGANISATION REPRESENTATIVES TO TAKE PART IN

https://rwi.lu.se/app/uploads/2017/10/EN-infoletter-Gender-in-Focus.pdf - 2026-06-19

1 I. CASE OVERVIEW The Saga of Win Process Cases: Criminal Case No. 1880/2560 Criminal Court Criminal Case No. Sor Wor Or 2564 Rayong Provincial Court Civil Case Sor Wor Por 2/2565 Rayong Provincial Court Civil Case Sor Wor Por 3/2567 Rayong Provincial Court Country/Region : Thailand Forum : civil and criminal courts Filing Date : Status : Decided Date of Judgement : Criminal Case No. 1880/2560 Cr

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Many countries strive for continued reductions in energy demand from new buildings as a way of mitigating the impact of climate change. Consequently, the importance of accurate and efficient building performance simulations (BPS) increases to improve the prediction in energy demand during the design-process for buildings. As observed in earlier studies, there is currently a performance gap between

Identifying the target proteins of bioactive small molecules is a key step in understanding mode-of-action of the drug and addressing the underlying mechanisms responsible for a particular phenotype. Proteomics has been successfully used to elucidate the target protein profiles of unmodified and ligand-modified bioactive small molecules. In the latter approach, compounds can be modified via click

Introduction: The aim was to create readily available algorithms that estimate the individual risk of β-amyloid (Aβ) positivity. Methods: The algorithms were tested in BioFINDER (n = 391, subjective cognitive decline or mild cognitive impairment) and validated in Alzheimer's Disease Neuroimaging Initiative (n = 661, subjective cognitive decline or mild cognitive impairment). The examined predictor

The aperiodic nature of geomagnetic field variations, both in intensity and direction, can aid in dating archaeological artefacts, volcanic rocks, and sediment records that carry a palaeomagnetic signal. The success of palaeomagnetic dating relies upon our knowledge of past field variations at specific locations. Regional archaeo- and palaeomagnetic reference curves and predictions from global geo

Intraischemic moderate hypothermia generally protects the brain against ischemic cell death, while hypothermia instigated several hours into the reperfusion phase is considered to be less effective. Here we report the effect of hypothermia (32.5°-33.5°C) of 5-h duration, initiated at 2, 6, 12, 24 and 36 h into the recirculation phase following 10 min of transient cerebral ischemia, on ischemic neu

Background: Autonomic neuropathy in diabetes, in addition to causing a range of symptoms originating from the autonomic nervous system, may increase cardiovascular morbidity. Our aim was to study the progression of autonomic neuropathy, based on symptom score and evaluation of an autonomic test, in persons with normal and impaired glucose tolerance and in patients with type 2 diabetes (T2D). Metho

New nanomaterials are constantly developed with applications in everything from cosmetics to high tech electronics. Assessing their biological impact has been done by analysis of their adsorbed protein corona, in vitro cell assays, and larger scale ecotoxicological studies. This has proved to be a huge challenge due to the wide range of available nanomaterials and their unpredictable behaviour in