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Background: Concizumab is an anti-tissue factor pathway inhibitor monoclonal antibody in development as a once-daily, subcutaneous prophylaxis for patients with haemophilia A or haemophilia B with or without inhibitors. We aimed to assess the efficacy and safety of concizumab in patients with haemophilia A or B without inhibitors. Here we report the results from the confirmatory analysis cutoff. M

Background: Treatment of newly diagnosed acute myeloid leukaemia (AML) is based on combination chemotherapy with cytarabine (ara-C) and anthracyclines. Five-year overall survival is below 30%, which has partly been attributed to cytarabine resistance. Preclinical data suggest that the addition of hydroxyurea potentiates cytarabine efficacy by increasing ara-C triphosphate (ara-CTP) levels through

This doctoral thesis consists of four independent research papers. All papers are empirical and cover the area of financial market risk, with a particular focus on systemic risk and volatility in financial markets.The first paper analyzes the joint effect of centrality and other characteristics that are essential in determining banks’ systemic importance. Specifically, centrality is treated as a m

Background: There are no evidence-based recommendations on the optimal time point to initiate non-vitamin K antagonist oral anticoagulants (NOACs) after acute ischemic stroke in patients with atrial fibrillation. We aimed to investigate the efficacy and safety of early versus delayed initiation of NOAC in these patients. Methods: TIMING (Timing of Oral Anticoagulant Therapy in Acute Ischemic Strok

Lubyanka- IIIrd Floor. Memoirs of the KGB-chairman Vladimir Semichastny This book (published in Czech language in 1998) gives the reader a chance to follow the development of those times as seen by one of the most powerful men of his days - the highest predecessor of the Commitee for State Security at the Council of Ministers of the USSR (better known under the abbreviation KGB). Considering his

In this paper I study how 1500 returned Swedish-Americans acted after their return to a mainly rural area of southern Sweden. The rural society in which the returnees grew up before immigrating to America was still largely a self-sustaining society albeit with a slowly expanding market economy. Most of the returnees came from a poorer background but quite a few of them experienced upward social mo

The hypoxic zone in the Baltic Sea has increased in area about four times since 1960 and widespread oxygen deficiency has severely reduced macro benthic communities below the halocline in the Baltic Proper and the Gulf of Finland, which in turn has affected food chain dynamics, fish habitats and fisheries in the entire Baltic Sea. The cause of increased hypoxia is believed to be enhanced eutrophic

Konkurrensen inom EU är reglerad genom konkurrensrätten i syfte att skapa och upprätthålla en effektiv marknad, den inre marknadens funktion samt välfärden för konsumenten. Förbudsregeln – se art. 101 FEUF och 2:1 KL – utgör tillsammans ett centralt verktyg som ska användas av kommissionen eller annan konkurrensmyndighet för att bryta upp otillåtna samarbeten mellan två eller fler företag, vilka äCompetition within the European union is regulated through a system of competition rules, with the purpose of creating and maintaining an efficient market, the function of the inner market and the consumer welfare. The prohibition rule – see art. 101 TEUF and 2:1 KL – constitutes together an essential tool that ought to be used to break up unwarranted collaborations between two or more undertaking

Häktning är det mest ingripande av våra personella tvångsmedel. Oskyldig eller inte följer det av svensk lag att varje intagen ska behandlas med respekt för sitt människovärde. Vidare ska verkställigheten av häktningen utformas så att negativa följder motverkas, med sådana följder avses bland annat psykiska, sociala och ekonomiska konsekvenser som kan följa av ett frihetsberövande. Om det finns riPre trial detention is a coercion measure where a suspect is incarcerated between the time he or she is being arrested until the trial. A pre trial detainee is considered innocent until proven guilty and thus it is important that the detention is not used as a punishment or rehabilitation. Whether a detainee is innocent or not he or she should be treated with respect for his or her human dignity.

Cardoso_et_al-2018-Journal_of_Comparative_Neurology(1).pdf R E S E A R CH AR T I C L E Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats Tiago Cardoso1,2 | Andrew F. Adler1,2 | Bengt Mattsson1,2 | Deirdre B. Hoban1,2 | Sara Nolbrant1,2 | Jenny Nelander Wahlestedt1,2 | Agnete Kirkeby1,3 | Shane Grealis

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_j_comp_neurol.pdf - 2026-05-30

Due diligence is a quite old concept. Already in the end of the 19th century, it was discussed in matters concerning neutrality. Since then, the concept of due diligence has extended to other areas of law. The fields of international law under examination in this thesis are international environmental law, the protection of the marine environment, diplomatic law, the treatment of aliens and the se

CÖS ASP (klar)_eng-GB_rev MS Postal address Box 117, 221 00 Lund Visiting address LUX, Bldg. B, Helgonavägen 3 Telephone +46 46 222 83 15 Email kristina.arnrup_thorsbro@kansliht.lu.se Website www.ht.lu.se Facu l ty Board ’s work ing com mi t tee General syllabus for third-cycle studies for the Degree of Doctor in East and South-East Asian Studies This syllabus was approved by the Board of the Join

https://www.ace.lu.se/sites/ace.lu.se/files/2022-08/general_syllabus_phd_asian_studies.pdf - 2026-05-30

Rapport vecka 13 (publicerad 2021-04-07) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 4 Aktuell status 4 10 postnummerområden med högst uppskattad förekomst av symtomatisk covid-19 31 mars . . . . 6 10 postnummerområden med lägst uppskattad förekomst av symtomatisk covid-19 31 mars . . . . 8 Störst ökning senaste 7 dagarna . . . . . . . . . . . . . . . . . . . . . . . . . . .

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/2021-04/rapport_vecka13_CoSS.pdf - 2026-05-30

SASNET Activity Report 2021 SWEDISH SOUTH ASIAN STUDIES NETWORK 2 SASNET ACTIVITY REPORT 2021 3SASNET ACTIVITY REPORT 2021 Table of Contents SASNET ACTIVITY REPORT 2021 5 WEBINARS AND PODCASTS 6 Webinars and exhibition 6 Podcast 7 WORKSHOPS 8 RESEARCH 9 Isha Dubey’s postdoctoral research project in summary 9 JOURNAL ARTICLES 10 WORKS IN PROGRESS 11 Amrita Ghosh 12 Isha Dubey 13 SASNET PUBLICATIONS

https://www.sasnet.lu.se/sites/sasnet.lu.se/files/2022-02/SASNET_Activity-report_2021.pdf - 2026-05-30

Advice and instructions for thesis defences at Faculty of Science Page 1 of 13 Postal address Science Faculty Office, Box 118, 221 00 Lund Visiting address Sölvegatan 27 Telephone 046-2224424, (switch) 046-222 00 00 E-mail: disputationer@science.lu.se Science Faculty Office ADVICE AND INSTRUCTIONS Date 2025-11-13 Advice and instructions to the doctoral student and the department in connection with

https://www.science.lu.se/sites/science.lu.se/files/2025-11/advice-instructions-thesis-defence-251113.pdf - 2026-05-30

KAFKA KONSTNÄRLIGA FAKULTETSKANSLIETS SERVICEKATALOG 2 KONSTNÄRLIGA FAKULTETSKANSLIETS SERVICEKATALOG KAFKA INLEDNING 3 FAKULTETSKANSLIETS UPPDRAG 3 KANSLICHEF 4 HR 4 Arbete på fakultetsövergripande nivå 4 Arbete med Lunds universitets centrala funktioner 4 Arbete med de enskilda högskolorna/centrumbildningarna 4 DET SYSTEMATISKA ARBETSMILJÖARBETET 6 Arbete med Lunds universitets centrala funktion

https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/kafka_tjanstekatalog_kansli_k_2.pdf - 2026-05-30

Bacterial abundance and production were studied in different zones in the Southern Ocean (39-62degreesS, 4-14degreesE) during a cruise in December-January 1997/1998. The role of potential growth limitation of bacteria due to limited availability of organic carbon (glucose) or inorganic N and P was studied in parallel. A positive correlation between surface water temperatures (-2 to 18 degreesC) an

Introduction Metabolic dysfunction is one of the hallmarks of sepsis yet little is known about local changes in key organs such as the heart. The aim of this study was to compare myocardial metabolic changes by direct measurements of substrates, such as glucose, lactate and pyruvate, using microdialysis (MD) in in-vivo porcine endotoxemic and hemorrhagic shock. To assess whether these changes were

1. To investigate further the release, localization and identity of a non-nitrergic mediator of smooth muscle relaxation in the female pig urethra, we studied the effects of drugs acting at alpha 2-adrenoceptors or K+ channels, the effects of capsaicin and chemical sympathectomy, and the actions of several transmitter candidates. 2. Electrical field stimulation (EFS; frequencies above 12 Hz) of sp

Background Hazardous drinking has been associated with an increased postoperative complication rate after surgery. Common complications include postoperative infections, cardiopulmonary complications, and bleeding episodes. Preoperative abstinence may to some degree reverse alcohol-induced pathophysiological processes and thus prevent postoperative complications. Objectives To assess the effect of