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WNT5A signaling and MARCKS phosphorylation in melanoma cell migration and invasion

The positive correlation between elevated expression of wingless-type mammary tumor virus integration site family member 5A (WNT5A) and metastatic potential in melanoma has been extensively explored. However, detailed mechanistic aspects regarding how WNT5A promotes increased melanoma aggressiveness remains unknown. Myristoylated alanine-rich C-kinase substrate (MARCKS), an intracellular protein c

Putsfasader i kustmiljö - En undersökning av havsnära putsfasader i västra Skåne

Kustnära putsade fasader ställda mot havet har av rapportförfattarna observerats vara i sämre skick än fasader med riktning inåt landet i samma miljö. Detta leder till hypotesen att saltvatten påskyndar nedbrytningen av kalk/cementbruk genom saltsprängning eller annan form av vittringsprocess. Ingen form av kemisk nedbrytning är rimlig då salt inte reagerar med putsens vanliga beståndsdelar. SvensOf rendered façades in coastal environment Rendered coastal-facing façades have been observed to be in worse condition than those facing away from the coastline in the same environment. This leads to the hypothesis that salt water accelerates the deterioration of render, either by salt blasting or through other forms of weathering processes. Since salt does not react with common render components,

A Hydrogeological Investigation of the Chocaya Alluvial Fan in Cochabamba, Bolivia

En grundvattenundersökning i ett område präglat av vattenrelaterade problem. Staden Cochabamba i Bolivia står inför flera vattenrelaterade utmaningar såsom brist på ytvatten, en ökande vattenanvändning, urbanisering och en sjunkande grundvattennivå. Samtidigt råder det en brist på kunskap angående de processer som påverkar grundvattnet i området. Något som detta examensarbete ämnar att förändra. The Central Valley of Cochabamba is located in the Andes mountain range, Bolivia. This region experiences several water related challenges such as a scarcity of surface water, an increasing water demand, a growing urbanization in groundwater recharge areas, and a declining water table due to intensive groundwater extraction. The valley has been influenced by both alluvial and fluvial depositions t

Affärsutveckling – från produkt till helhetslösning

Problem definition: In recent years, Kalmar has received an increased number of requests and indications from the market concerning automated solutions in the industry. In the paper industry this is mainly caused by the increased costs in the customer's key processes that possibly could be reduced by fully automated solutions. However, there is currently no clear view of the market potential a

The Adventure Continues and Human Rights Remain Central

The Adventure Continues and Human Rights Remain Central Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus Areas Business and Human

https://rwi.lu.se/2016/01/20/the-adventure-continues-and-human-rights-remain-central/ - 2026-05-08

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1. Course Details 1. Course code SAS H09 2. Course title Ancient Egypt and Its Influence on Early European Cultures 3. Cycle (1st, 2nd or 3rd) 1st [Undergraduate] 4. Higher education credits 7.5 5. Details of approval of course Syllabus approved by the Syllabus Committee of the Faculty of the Humanities and Theology 7th March 2008. 6. Details of changes approved 2. General Information 1. Field(s)

https://www.ark.lu.se/media/utbildning/dokument/kursplaner/SASH09_eng.pdf - 2026-05-08

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Lokalt samarbetsavtal för AkademikerAlliansen i XX kommun Detta samarbetsavtal avser lokal samverkan mellan de förbund inom AkademikerAlliansen som väljer teckna detta avtal. 1.0 Ändamål 1.1 Avtalets syfte är att reglera förutsättningarna som ska gälla mellan de förbund som ingår i föreningen. 2.0 Bildande av den lokala föreningen 2.1 Utgångspunkten för att bilda lokal förening är att det är frivi

https://www.saco.se/globalassets/lokala-akademikerforeningar/kommun-och-region/akademikeralliansen/dokument/alliansforening/mall_lokalt-samarbetsavtal_akademikeralliansen_2023.docx - 2026-05-08

Pedagogical-Paper-HT-2023-Soderberg

Pedagogical-Paper-HT-2023-Soderberg LTH:s 12:e Pedagogiska Inspirationskonferens, 7 december 2023 Reducing Free-riders by Individual Achievement Tracking in Group Work Emma Söderberg, Dept. of Computer Science, LTH Abstract—Most people involved in courses with group work, both as students and as teachers, are aware of the problem of free-riders. In courses where group work is combined with forms

https://www.lth.se/fileadmin/cee/genombrottet/konferens2023/F1_So__derberg.pdf - 2026-05-08

Comorbidities and mortality in subgroups of adults with diabetes with up to 14 years follow-up : a prospective cohort study in Sweden

Background: Subgroups of adult-onset diabetes, namely severe autoimmune diabetes (SAID), severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes (SIRD), and mild obesity-related diabetes (MOD) or mild age-related (MARD) diabetes, have been defined with clinical variables and a machine-learning approach. Our aim was to describe their long-term outcomes and mortality. Methods: In

Modifying Cooking Practices to Reduce the Formation of Heterocyclic Amines

Popular Abstract in Swedish Vid tillagning av kött, och framför allt stekning och grillning, bildas mutagena ämnen i stekskorpan. Dessa ämnen benämns heterocykliska aminer. Flera epidemiologiska studier har visat ett samband mellan uppkomsten av cancer och intaget av heterocykliska aminer, medan några studier inte finner något samband. Ämnena har också visat kunna utveckla tumörer och cancer i djuCommonly cooked meat dishes contain heterocyclic amines (HAs) at ng/g levels. HAs are animal carcinogens, form DNA adducts in human tissues, and have been associated with increased risk of cancer in epidemiological studies, and it is thus recommended that human intake be decreased. The aim of this investigation was to find ways of modifying cooking practices to reduce the formation of HAs. Various

Towards a High Quality Real-Time Graphics Pipeline

Popular Abstract in Swedish Datorgrafik handlar om att övertyga betraktaren. En huvuduppgift är att generera verklighetstrogna bilder utifrån tredimensionella modeller. Med hjälp av datorer simuleras hur dessa modeller interagerar med ljus. Betraktaren skall helst inte reflektera över om bilden han ser är ett fotografi eller en helt och hållet genererad bild. I denna avhandling presenteras algoritModern graphics hardware pipelines create photorealistic images with high geometric complexity in real time. The quality is constantly improving and advanced techniques from feature film visual effects, such as high dynamic range images and support for higher-order surface primitives, have recently been adopted. Visual effect techniques have large computational costs and significant memory bandwid

Effect of molecular weight of polyacrylic acid (PAA) on polyethersulfone membrane structure and performance

The novel method of modification of polyethersulfone (PES) ultrafiltration membranes is proposed. This method involves the use of aqueous solutions of polyacrylic acid (PAA) of different molecular weights (Mn=5.1×103 g·mol–1, Mn=490×103 g·mol–1) as a coagulant in non-solvent induced phase inversion process (NIPS). Addition of PAA (0.05–1.5 wt%) to the coagulation bath leads to marked changes in pe

Elite and non-elite agenda-setting on Twitter: the case of #almedalen 2018

In this paper, we study activity on Twitter in relation to the Swedish political festival Almedalsveckan, a week-long event where political parties, interest organizations, corporations and other actors for decades have gathered on the island of Gotland to discuss politics and public affairs. In 2018, a total of 4311 events (speeches, seminars, debates etc.) were arranged by 1929 separate actors a

Wireline Communications in a Wireless World

The whole society is digitalizing, filled with streaming services, cloud computing and an ambition of ubiquitous connectivity. To address the data demand, ultra-fast broadband, at the speeds of 1Gbps and more, is developed and deployed. Optical fibers have been long viewed as a future-proof carrier for the ultra-fast broadband. However, the physical deployment of fiber networks, including digging,

Physiological aspects on intracardiac blood flow

Magnetic resonance imaging enables detailed in vivo study of complex flow through 3D, time-resolved phase contrast imaging (4D flow). 4D flow may reveal previously unknown aspects of the physiology of intracardiac blood flow, and possibly elucidate pathophysiological processes that have yet to manifest themselves outside the heart.The purpose of this thesis is to examine the physiological role of

Using peer assisted learning to empower first-year students and helping them experience success

The workshop will focus on what first-year students to higher education needs to be successful and how a peer learning programme might address those needs. (~5 min for introduction)The workshop will start with a brainstorm session where participants in small groups will share thoughts and ideas on the question (~20 min for activity): “What would you like to affect with your new students? Provide s

Safeguarding of quinoa beverage production by fermentation with Lactobacillus plantarum DSM 9843

Plant-based beverages are increasing in popularity and quinoa is an attractive option. A hygienic implication linked to the production of beverages from raw material originating from plants is the high microbial contamination. The safety of the product can be guaranteed by lactic acid fermentation, and by using a probiotic strain as starter culture for the fermentation, the final product will bene

Comprehensive proteome analysis of nasal lavage samples after controlled exposure to welding nanoparticles shows an induced acute phase and a nuclear receptor, LXR/RXR, activation that influence the status of the extracellular matrix

Background: Epidemiological studies have shown that many welders experience respiratory symptoms. During the welding process a large number of airborne nanosized particles are generated, which might be inhaled and deposited in the respiratory tract. Knowledge of the underlying mechanisms behind observed symptoms is still partly lacking, although inflammation is suggested to play a central role. Th

Oligomerization of human and bacterial frataxin : Structural and functional studies

Iron is a one of the critical elements in our life, being the most common element on earth, forming most of the inner and outer earth’s core. In our bodies iron is required in small amounts for biological processes to be performed. It is recommended to eat food containing iron to avoid common health problems such as anemia. A slight increase or decrease in iron levels above or below normal in liviFriedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disease caused by defeciency in frataxin, a highly conserved protein central to iron homeostasis in mirochondria. The function of frataxin is related to its capability to bind, store and deliver iron to different biochemical process such as iron-sulfur cluster assembly and heme biosynthesis. Most FRDA pateints have extended GAA

Runaway gas accretion and gap opening versus type I migration

Growing planets interact with their natal protoplanetary disc, which exerts a torque onto them allowing them to migrate in the disc. Small mass planets do not affect the gas profile and migrate in the fast type-I migration. Although type-I migration can be directed outwards for planets smaller than 20−30M⊕ in some regions of the disc, planets above this mass should be lost into the central star lo