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What determines the current presence or absence of permafrost in the Tornetrask region, a sub-arctic landscape in Northern Sweden?

In a warming climate, permafrost is likely to be significantly reduced and eventually disappear from the sub-Arctic region. This will affect people at a range of scales, from locally by slumping of buildings and roads to globally as melting of permafrost will most likely increase the emissions of the powerful greenhouse gas methane, which will further enhance global warming. In order to predict fu

galaxieEST: addressing EST identity through automated phylogenetic analysis

Background: Research involving expressed sequence tags ( ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and satisfactory annotated public sequence libraries are, however, available only for a limited range of organisms, rendering the absence of sequences and gene structure information a tangible problem for those working with ta

Rho Kinase-related Proteins in Human Vaginal Arteries: An Immunohistochemical and Functional Study

The calcium-sensitizing Rho A/Rho kinase pathway has been suggested to play a role in the control of nongenital vascular smooth muscle. Rho-associated kinases (ROKs) cause calcium-independent modulation of smooth muscle contraction, and have been demonstrated in the bladder, prostate, and corpus cavernosum. Until now, it is not known whether ROKs and related proteins play a role in the control of

Influence from fuel type on the performance of an air-blown cyclone gasifier

Entrained flow gasification of biomass using the cyclone principle has been proposed in combination with a gas engine as a method for combined heat and power production in small to medium scale (<20 MW). This type of gasifier also has the potential to operate using ash rich fuels since the reactor temperature is lower than the ash melting temperature and the ash can be separated after being collec

Evaluation of new active technology for low-energy houses

Popular Abstract in Swedish Bostäder och service svarar för hela 36 procent av Sveriges totala energianvändning, av detta står bostäder och lokaler för ungefär 86 procent. Den svenska riksdagen har antaget EU: s klimat-och energipolitiska mål som skall nås till 2020, som kallas "20-20-20"-målen. EU:s 20-20-20-mål innebär att vi ska minska klimat¬påverkan med 20 procent, uppnå 20 procent förnybar eUsing energy at low-quality levels opens up new possibilities for low-energy houses. Low-quality energy can be heat at a temperature that is close to that of its surrounding, and can be used, for example, to pre-heat ventilation air or domestic hot water. Pre-heating the incoming outdoor air reduces the need to heat ventilation and reduces the need for high-quality energy such as electricity or he

Vitreoscilla hemoglobin. In vitro mutagenesis and transcript profiling to improve its biotechnological usefulness

Vitreoscilla is an obligate aerobic bacterium found in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla induces the production of a homodimeric hemoglobin (VHb) when subjected to oxygen-limiting conditions. It is thought that VHb facilitates oxygen delivery to the respiratory apparatus of its host by increasing the local oxygen concentration under oxygen-

Synthetic analogs of sialyl Lewis x

The sialyl Lewis x (SLex) tetrasaccharide is the smallest recognizable ligand for selectins. The selectins constitute a vital part of the inflammatory cascade for recruitment of leukocytes to a site of tissue damage or microbial infection. If too many leukocytes are recruited, normal, not injured, cells can be damaged; a process known from chronic inflammatory diseases such as reumatoid arthritis,

Ser129 phosphorylation of endogenous α-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and function.

Phosphorylation of the α-synuclein (α-syn) protein at Ser129 [P(S129)-α-] was found to be the most abundant form in intracellular inclusions in brains from Parkinson's disease (PD) patients. This finding suggests that P(S129)-α-syn plays a central role in the pathogenesis of PD. However, it is at present unclear whether P(S129)-α-syn is pathogenic driving the neurodegenerative process. Rodent stud

CD40L is not involved in acute experimental pancreatitis

Recent data suggest that platelets not only control thrombosis and hemostasis but may also regulate inflammatory processes such as acute pancreatitis. However, the specific role of platelet-derived mediators in the pathophysiology of acute pancreatitis is not known. Herein, we examined the role of CD40 ligand (CD40L, CD154) in different models of acute pancreatitis. Acute pancreatitis was induced

Evaluation of the Mechanical Properties of PMMA Reinforced with Carbon Nanotubes - Experiments and Modeling

The effective mechanical properties of polymethyl-methacrylate (PMMA) reinforced with carbon nanotubes (CNTs) were evaluated by means of two approaches: experiments and a micromechanical model. With various concentrations of CNTs, two specimen fabrication processes were examined: hot pressing (HP) and injection molding (IM). Experiments included a series of uniaxial tensile tests guided by an ASTM

Origins and projections of nerve fibres in rat pyloric sphincter.

Nerve fibres play an important role in the regulation of gastric emptying. The aims of this study were to clarify the distribution, projections and origin of neuronal type nitric oxide synthase (NOS)-, tyrosine hydroxylase (TH)-, vesicular acetylcholine transporter (VAchT)- and peptide-containing nerve fibres of the rat pyloric sphincter. Extrinsic and local denervations of the sphincter were perf

Use of neural networks to improve quality control of interpretations in myocardial perfusion imaging

Background: The aim of this study was to explore the feasibility of using a technique based on artificial neural networks for quality assurance of image reporting. The networks were used to identify potentially suboptimal or erroneous interpretations of myocardial perfusion scintigrams (MPS). Methods: Reversible perfusion defects (ischaemia) in each of five myocardial regions, as interpreted by on

Challenging the strategy paradigm within the paper packaging industry

Formulating and implementing a new strategy may be a challenging task, especially if it alters the way in which a company has operated and positioned itself before. This may be particularly true for companies within the forest industry, like manufacturers of paper packaging products, pursuing differentiated customer value and innovative solutions where, traditionally, success has been measured in

Ecosystem services - current challenges and opportunities for ecological research

e concept of ecosystem services was originally developed to illustrate the benefits that natural ecosystems generate for society and to raise awareness for biodiversity and ecosystem conservation. In this article we identify major challenges and opportunities for ecologists involved in empirical or modeling ecosystem service research. The first challenge arises from the fact that the ecosystem ser

Is it a policy crisis or it is a health crisis? The Egyptian context--analysis of the Egyptian health policy for the H1N1 flu pandemic control.

A new influenza virus that was first detected in people in April 2009, was initially referred to colloquially as "swine flu", since it contained genes from swine, avian and human influenza viruses. It can, however, not be transmitted by eating pork or dealing with pigs. In Egypt, several hundred thousand pigs were killed in May, in spite of advice from global health authorities that such an action

Mapping, development and optimization of internal logistics in a multi-stage production facility

Title: Mapping, development and optimization of internal logistics in a multi- stage production facility Authors: Nils Jönsson and Björn Hofbard Supervisors: Eva Berg, Department of Industrial Management and Logistics. Conny Andersson, Sandvik Background: In highly dynamic and competitive environments, supply chain management and logistics can create important advantages against competitors. Since

Conceptual Dynamic Analysis of a Vehicle Body

När en ny bil skall designas är det viktigt att kunna förutse vissa fenomen innan en fysisk prototyp finns tillgänglig. Ljudet som orsakas av vägen är ett av dessa fenomen. På grund av känsligheten och komplexiteten i metoderna som används idag vore det intressant ifall man kan använda något enkelt mått för att få en känsla för detta fenomen i en tidig konceptutvecklingsfas. Frågan blir då, vilketThe noise, vibration and harshness (NVH) and body dynamic performance of automotive vehicles is highly dependent of the components included in the body structure and compartment, since they add mass, stiffness and damping to the overall structure. Today, the noise levels in the compartment are predicted using complex and detailed computational models during both early and late stages of the vehicl

Barnperspektivet - en studie av hur rättsordningen garanterar att unga brottsoffer får upprättelse

Barn har ett särskilt skyddsvärde och när de utsätts för brottsliga gärningar har de, precis som vuxna, ett behov av upprättelse men också en rätt att få uppleva att rättvisa skipas för att få ett avslut på brottsupplevelsen. I Sverige tillmäts den rättsliga hanteringen av unga brottsoffer stor betydelse för utgången i målet och det ställs således höga krav på att barnets särskilda behov tas i bea