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In the region of Three Gorges Reservoir (TGR) in China, there has been occurrence of several frequent earthquakes of moderate intensity since reservoir impounding occurred in 2003. These earthquakes are generally believed to be induced by reservoir impoundment and water-level variations. Usually, the geo-stress will change, when natural earthquakes occur. Following this principle, this paper adopt

Background: Tobacco smoking and alcohol consumption have been intensively studied in the general population to assess their effects on the risk of breast cancer, but very few studies have examined these effects in BRCA1 and BRCA2 mutation carriers. Given the high breast cancer risk for mutation carriers and the importance of BRCA1 and BRCA2 in DNA repair, better evidence on the associations of the

När en väljare röstar med andras beteende i åtanke och politikutfall i sikte är det en "strategisk" röst. Den här studien relaterar väljares strategiska överväganden till olika steg i regeringsbildningsprocessen: att ta plats i parlamentet, ingå i regering, och påverka politikutfallet. Detta innebär att väljaren ibland tänker som ett parti på vad rösten kan få för konsekvenser. Utifrån detta perspIf a voter defects from preference under the consideration of policy outcomes and others' behavior, it is a "strategic vote". This thesis relates voters' strategic considerations to the government formation process: the chances for a party to gain seats, enter office, and affect overall policies. This implies that voters sometimes think like parties on the governmental consequences of the vote. Fr

OBJECTIVE: B-type natriuretic peptide (BNP) has been established as a biomarker for heart failure. The objective was to evaluate BNP measured on arrival in the intensive care unit (ICU) as a predictor for heart failure defined as need for inotropic support or IABP beyond 24 hours postoperatively after aortic valve replacement. DESIGN: A prospective, observational study. SETTING: A cardiothoracic s

Background Medical adherence is important in the treatment of depression. Primary medical adherence, i.e. patients collecting their newly prescribed medications from pharmacies, is very different depending on the drug prescribed Objective To assess the rate of primary medical adherence in patients prescribed antidepressants and to identify characteristics that make patients less likely to pick up

Aim: We aimed to study the feasibility and tolerability of a combination therapy consisting of glutamic acid decarboxylase (GAD-alum), Etanercept and vitamin D in children and adolescents with newly diagnosed with type 1 diabetes (T1D), and evaluate preservation of beta cell function. Material and Methods: Etanercept Diamyd Combination Regimen is an open-labelled multi-centre study pilot trial whi

AIMS: Patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) have increased prevalence of atrial arrhythmias indicating atrial involvement in the disease. We aimed to assess the long-term evolution of P-wave indices as electrocardiographic (ECG) markers of atrial substrate during ARVC progression. METHODS AND RESULTS: We included 100 patients with a definite ARVC diagnosis according

Land ecosystems contribute to climate change mitigation by taking up approximately 30% of anthropogenically emitted carbon. However, estimates of the amount and distribution of carbon uptake across the world's ecosystems or biomes display great uncertainty. The latter hinders a full understanding of the mechanisms and drivers of land carbon uptake, and predictions of the future fate of the land ca

The thesis explores the ‘missing link’ in the study of priority-setting for research, development, and innovation (RDI), namely the processes of implementing RDI priorities, and the consequences of these processes. It does so by focusing on how choices, actions, and motivations of implementers of RDI priorities established elsewhere in the policy system enact, or carry out, the priorities, resulti

Background: The ProtonCare Study Group (PCSG) was formed with the purpose to develop and implement a framework for evaluation of proton beam therapy (PBT) and the related care at a novel clinic (Skandionkliniken), based on patient reported data. Method: A logic model framework was used to describe the process of development and implementation of a structured plan for evaluation of PBT for all diag

Popular Abstract in Swedish 2003 års Nobelpris i kemi gick till professor Peter Agre för upptäckten av aquaporinerna. Aquaporiner är proteiner som sitter i membran och bildar kanaler som tillåter vatten och andra små neutrala molekyler att passera genom membranet. Aquaporinerna utgör en mycket gammal och välkonserverad proteinfamilj som finns i alla levande organismer som hittills undersökts. VäxAquaporins, or Major Intrinsic Proteins (MIPs), are integral proteins that facilitate transport of water and other small neutral solutes across biological membranes. They belong to a well conserved and ancient family of proteins, present in all organisms ranging from bacteria to plants and humans. The aquaporin family in plants is large, indicating complex and regulated water transport within the

Semiconductor nanowires are nanoscale objects formed by bottom-up synthesis. In recent years their unique properties have been exploited in fields such as electronics, photonics, sensors and the life sciences. In this work, the epitaxial growth of nanowires and their applications were studied. Heteroepitaxial growth of III-V nanowires on silicon substrates was demonstrated. This may enable direct

Purpose The research presented is the initial part of a project with the aim of increasing the use of end-user requirement through out the construction process. This initial part maps how Swedish real estate companies manage end-user requirements and evaluate the outcome. Methodological approach The focus of the study was on methods for capturing and managing end-user requirements and for measur

För mindre och nystartade aktiebolag kan finansiering vara ett gissel, särskilt om den verksamhet som bedrivs i bolaget är kostsam eller förenad med hög finansiell risk för potentiella finansiärer. Sådan är situationen ofta i det som i folkmun kallas ”startups”, då bolagen frekvent bygger på enbart en idé eller en outvecklad produkt, och därmed utgör mycket osäkra investeringar för poten- tiella fFunding for a small or newly established limited company can be difficult, especially if the operating objective in the company is associated with high costs and high financial risks for potential financiers. This is often the case for so called “start-ups”, as these types of companies are frequently based on an idea or an undeveloped product. Investing in a start-up is very risky for pot- ential

En kall eftermiddag den 23 december 1947 hände något fantastiskt på ett laboratorium i New Jersey, USA. Forskare vid Bell laboratoriet demonstrerade för första gången en funktionell transistor! Transistorn är en elektrisk komponent som har tre terminaler där man kan ansluta andra komponenter. Om man leder en ström eller spänning genom ett par av terminalerna kan man kontrollera strömmen genom ett As the limits of transistor feature size scaling is reaching its saturation, new innovations are needed to prevent performance loss. High performance transistors on the III/V semiconductor platform implemented with ferroelectric oxides might in the future satisfy this demand. But the integration of ferroelectrics on materials such as InAs degrades the substrate and other vital components from the

En ökad medvetenhet om värdet av ett rent grundvatten yttrar sig i allt fler sammanhang, bl.a. i det nationella miljömål om grundvatten av god kvalitet som riksdagen presenterat. Simrishamns kommun ser över vattenskyddsområdena runt kommunens grundvattentäkter för att säkerställa ett rent grundvatten. Målet med detta examensarbete är att ta fram ett underlag som skall kunna ligga till grund för avThe increased awareness of the value of clean groundwater can be seen in a growing number of contexts. This is also emphasized in the national environmental goals, put up by the Swedish government. The municipality of Simrishamn, in southern Sweden, is re-evaluating the extension of the existing restriction areas around the groundwater wells of the municipality. The aims in this investigation were

This Master Thesis describes the product development of a medical laboratory machine. The purpose of the project was to generate and evaluate different concepts of a device that is to be included in a bigger process named Dried Blood Spot testing (DBS) in which dried blood samples are collected and analyzed. The device developed here shall relocate the blood samples from a paper slip, mounted on a

The field of Cognitive Psychology has discovered a large number of automatic and systematic errors of judgement that humans make. These are called cognitive biases and cause irrational behavior in diverse contexts. Prior research has found that cognitive biases can cause irrational behavior in companies. For example company functions, such as planning, have been found to suffer from systematic err

Dagens krav på läkemedel är höga, de ska t.ex. stanna kvar i kroppen under lång tid, ha lång hållbarhetstid och vara lätt att dosera. Att PEGylera ett läkemedel kan ge dessa egenskaper. Idag är dock denna tillverkningsprocess långsam och ger ett lågt utbyte. Size Exclusion Reaction Chromatography (SERC) är en ny teknik som förhoppningsvis ska förbättra denna process. Protein är idag vanligt förekoThe PEGylation process is a covalent attachment between a protein (the pharmaceutical) and poly ethylene glycol (PEG) and since the beginning in 1977 PEGylation processes have been used to improve pharmaceuticals. PEGylation of a pharmaceutical achieves improved properties like greater solubility in water, longer residence time in vivo and extended shelf life. The PEGylation process is in general