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Preeclampsia is one of the most common causes of perinatal and maternal morbidity/ mortality. One suggested environmental risk factor is exposure to endocrine-disrupting pollutants such as per-and polyfluoroalkyl substances (PFAS). The present case-control study in southern Sweden aims to investigate the hypothesized association between serum concentrations of PFAS in early pregnancy and the risk

Aim: To investigate the associations between major foods and dietary fibre with subtypes of stroke in a large prospective cohort. Methods and results: We analysed data on 418 329 men and women from nine European countries, with an average of 12.7 years of follow-up. Diet was assessed using validated country-specific questionnaires which asked about habitual intake over the past year, calibrated us

Transitional care for adolescents with congenital malformations, such as anorectal malformations (ARM), is described sparsely in the literature and referred to as being inadequate. In order to organize future successful healthcare structures, knowledge of patient-reported important aspects of transition is required. The aim of the study was therefore to explore the needs and expectations of transi

The issue of Critical Raw Materials (CRMs) and potential interruptions to their supply andavailability due to concerns such as shortages, trade restrictions or geopolitical considerations are topicsthat are relatively unknown to the general public. Education and the dissemination of this informationamongst the general public has been promoted as a key factor in addressing this and enabling thetran

At a glucose concentration of 3mm or less, iodoacetamide had no effect on the release of insulin from microdissected pancreatic islets of ob/ob-mice. At higher glucose concentrations, iodoacetamide exerted both an initial stimulatory and a subsequent inhibitory action. When islets were perifused with 1mm-iodoacetamide and 17mm-glucose the inhibitory action predominated after about 15min of transie

The management of diabetic foot ulcers (DFU) remains a challenge, and there is continuing uncertainty concerning optimal approaches to wound healing. The International Working Group of the Diabetic Foot (IWGDF) working group on wound healing has previously published systematic reviews of the evidence in 2008, 2012 and 2016 to inform protocols for routine care and to highlight areas which should be

This study examines the role of the Sovereign ESG framework in assessing national progress toward Transformative Change (TC) via environmental, social, and governance metrics. Using data from the World Bank Sovereign ESG Data Portal, we conduct an empirical explorative quantitative study and analyze ESG development across country income groups to identify sustainability challenges and opportunitie

Hydrological models are generally calibrated and validated using a suite of well-known statistical metrics, which sometimes lack clear connection and tailoring to the local users’ need and therefore limits the evaluation, especially in the case of global climate services. Therefore, in this study, two types of application-based evaluation metrics are introduced, addressing (i) temporal matching of

Title: Women experiencing the second stage of labour for the first time: a qualitative free-text analysis within the Oneplus trial. Background: The second stage of labour is the time from full cervical dilation to the birth of the baby. The risks to the woman and the baby are increased during this stage, leading to intensified midwifery care. A positive birth experience is a significant goal of in

The provision of safe care is complex and difficult to achieve. Awareness of what happens in real time is one of the ways to develop a safe system within a culture of safety. At Great Ormond Street Hospital, we developed and tested a tool specifically designed for patients and families to report harm, with the aim of raising awareness and opportunities for staff to continually improve and provide

The purpose of this study was to examine what social workers include in the term "parenting ability". More specifically the purpose was to investigate how social workers view the parenting ability among parents with an intellectual disability. Furthermore the aim was to examine what difficulties social workers come across in their work with families where one of the parents are intellect

Purpose: WST11 vascular targeted photodynamic therapy (VTP) is a local ablation approach relying upon rapid, free radical-mediated destruction of tumor vasculature. A phase III trial showed that VTP significantly reduced disease progression when compared with active surveillance in patients with low-risk prostate cancer. The aim of this study was to identify a druggable pathway that could be combi

The Paris Agreement establishes a transparency framework for anthropogenic carbon dioxide (CO2) emissions. It's core component are inventory-based national greenhouse gas emission reports, which are complemented by independent estimates derived from atmospheric CO2 measurements combined with inverse modelling. It is, however, not known whether such a Monitoring and Verification Support (MVS) capac

Stay-at-home recommendations to reduce the spread of the COVID-19 virus have had a major impact on people's everyday lives. However, while the evidence indicates that such recommendations have caused distress, anxiety, and fear among the public, little is known about how persons living with complex health conditions, e.g., disability after stroke, have experienced and handled the situation. We int

OBJECTIVES: To compare treatment retention between biosimilars and their originator products among first starters (etanercept, infliximab, adalimumab and rituximab), as well as after non-medical switch. METHODS: Patients with rheumatic diseases starting, for the first time, an originator or biosimilar etanercept, infliximab, adalimumab or rituximab were identified in the national Swedish Rheumatol

Background: Understanding current patterns of functional decline will inform patient care and has health service and resource implications. Aim: This prospective consecutive cohort study aims to map the shape of functional decline trajectories at the end of life by diagnosis. Design: Changes in functional status were measured using the Australia-modified Karnofsky Performance Status Scale. Segment

Ear acupuncture is used as a non-pharmacological complement in psychiatric and addiction care to reduce anxiety, depression and insomnia. The aim of this study was to describe health care professionals' perceptions of giving ear acupuncture in different psychiatric settings. Twenty-four professionals providing ear acupuncture to patients with a variety of psychiatric symptoms and/or addiction were

The odorant receptors (ORs) of insects are crucial for host and mate recognition. In moths (Lepidoptera), specialized ORs are involved in male detection of the sex pheromone produced by females. Most moth sex pheromones are C10-C18 acetates, alcohols, and aldehydes (Type I pheromones), and most pheromone receptors (PRs) characterized to date are from higher Lepidoptera (Ditrysia), responding to th

Timing of return to the breeding area presumably optimizes breeding output in migrants. How timing affects the other components of fitness — survival, has been comparatively little studied. Returning too early in spring is expected to be associated with high mortality in insectivorous migrants when weather conditions are still unsuitable. Yet, males in particular arrive early to get access to the

Aims: To investigate to what extent socioeconomic differences in swimming abilities persist among children in the city of Malmö, Sweden, after a community-level swimming intervention programme in public primary schools. Methods: A compulsory swimming education programme was launched in 2014 in second grade (at age 8) in all public primary schools in Malmö, Sweden. Data for the present study on soc