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Context: The age-related decline in dehydroepiandrosterone (DHEA) levels is thought to be of importance for general and vascular aging. However, data on the association between DHEA and mortality are conflicting. Objectives: We tested the hypothesis that low serum DHEA and DHEA sulfate (DHEA-S) levels predict all-cause and cardiovascular disease (CVD) death in elderly men. Design, Setting, and Par

This thesis is an exploratory, descriptive and comparative study of teachers’ focus and teaching methods in Spanish as a third language (L3) in Sweden. The curriculum of Modern Languages emphasizes communicative competence and the purpose of the study is to examine how this is applied in the teaching of the course Spanish 4 and how the students progress during the course. Five teachers at four Sen

Hypoxia is a hallmark of solid tumors, which may offer opportunities for targeted therapies of cancer; however, the mechanisms that link hypoxia to malignant transformation and tumor progression are not fully understood. Here, we show that up-regulation of the polyamine system promotes cancer cell survival during hypoxic stress. Hypoxia was found to induce polyamine transport and the key enzyme of

BACKGROUND: There is conflicting evidence that traffic-related air pollution is a risk factor for allergic conditions. Few studies have investigated this in adults. In adults, a high proportion of asthma, rhinitis and eczema is triggered by non-allergic factors. We investigated traffic as a risk factor for allergic versus non-allergic asthma and rhinitis, and eczema, in adults. A questionnaire fro

PURPOSE: Pancreatitis is an inflammatory state of the pancreas, for which high-performing serological biomarkers are lacking. The aim of the present study was to evaluate the use of affinity proteomics for identifying potential markers of disease and stratifying pancreatitis subtypes. EXPERIMENTAL DESIGN: High-content, recombinant antibody microarrays were applied for serum protein expression prof

In this paper we revisit the contentious issue of whether corporate governance arrangements influence corporate cash holdings. We use the exogenous cash windfalls in the oil industry during the 2000s to test the power of three governance dimensions (managerial entrenchment, board independence and ownership) in explaining differences in cash management policies. Between 2000 and 2008 the oil price

Supply chains are difficult to plan because they involve complex relationships that influence supply chain performance. In this paper, discrete-event simulation (DES) is discussed in order to identify if it could be a technique used to improve supply chain planning. Two DES models have been developed and are used in this paper to find out whether DES could be a technique for unraveling the complex

Background. Anaemia in haemodialysis patients can be effectively treated with erythropoietin. We investigated whether subcutaneous (SC) epoetin β administered once weekly was as effective as the same weekly dosage given in two to three divided doses. Methods. One hundred and fifty-eight patients (delivered Kt/V >1.0, where K=dialyser-renal urea clearance, t=dialysis time and V=filtration volume, o

The possibility of using radio over fiber (RoF) analog transmissions to characterize the wireless propagation channel of distributed antenna systems is investigated. In particular, the coherence time of kilometer-long, fiber-based networks is analyzed. Joint measurements of the phase noise of parallel links to the same site (intra-site) and to different sites (inter-site) in such a network are pre

The aim is to investigate the associations between economic stress in childhood and adulthood, and low generalized trust in other people, testing two life course hypotheses. The 2008 public health survey in Scania is a cross-sectional postal/mail questionnaire study in which 28,198 persons aged 18-80 participated (55% participation in the original sample). Logistic regressions were used to analyze

BACKGROUND: Recent studies have suggested that melatonin-a hormone produced by the pineal gland under circadian control-contributes to PD-related sleep dysfunction. We hypothesized that degenerative changes to the neural structures controlling pineal function (especially the suprachiasmatic nuclei of the anterior hypothalamus) may be responsible for reduced melatonin output in these patients. We c

The long-term psychological effects resulting from carrier testing and prenatal diagnosis (PD) of haemophilia were evaluated by comparing mental symptomatology scores (Symptom Check List, SCL-90) for 50 carriers of haemophilia who had undergone PD about five years earlier, 55 carriers who had not undergone PD and 262 control women who were not carriers. All of the women had children. Carrier testi

Introduction: Hip fractures are commonly diagnosed by plain radiography. When a patient presents with negative radiographs and high clinical suspicion of fracture, guidelines recommend proceeding with magnetic resonance imaging (MRI) to diagnose the patient. The aim of this study was to assess the use of MRI in diagnosing hip fractures following trauma to the hip and describe clinical outcome afte

A new method to determine the concentration of the free protein S in plasma is described. It is an enzyme-linked ligandsorbent assay (ELSA) which utilises the protein S binding capacity of the natural ligand C4b-binding protein (C4BP) to capture the free protein S from plasma samples. The use of C4BP as ligand in the assay is possible due to the high affinity (Kd = 0.1 nM) of the interaction betwe

Best use of scientific knowledge is required to maintain the fundamental role of seafood in human nutrition. While it is acknowledged that genomic-based methods allow the collection of powerful data, their value to inform fisheries management, aquaculture, and biosecurity applications remains underestimated. We review genomic applications of relevance to the sustainable management of seafood resou

In the effort to separate pedestrian and bicycle traffic from motorised traffic the solution often is to let the pedestrians and bicyclists share space. However, combined pedestrian and bicycle paths lead to problems for both pedestrians and bicyclists; for pedestrians it is a security and safety problem and for bicyclists a mobility problem. Seniors and visually impaired pedestrians are especiall

Purpose – In the last decade, greater attention has been paid to the role of management accounting and control (MAC) in making professional organizations more horizontal. The authors argue that earlier research has not shown how the interrelatedness between professional identities and MAC influences attempts to make organizations more horizontal. In this paper the authors respond to the call for m

It is well known that Max-Weight type scheduling algorithms are throughput optimal since they achieve the maximum throughput while maintaining the network stability. However, the majority of existing works employing Max-Weight algorithm require the complete channel state information (CSI) at the scheduler without taking into account the associated overhead. In this work, we design a Scheduling and