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Sexual selection as a promoter of population divergence in male phenotypic characters: a study on mainland and islet lizard populations

Sexual selection is often viewed as a promoter of population divergence, although some forms of sexual selection could rather hamper divergence. In the present study, we investigated whether sexual selection promotes divergence in sexually-selected traits. We studied population variation in sexual selection in relation to colour morph and body size in islet and mainland populations of the Skyros w

Tentative (id)entities: On technopolitical cultures and the experiencing of genetic testing

The practices around genetic testing for hereditary breast and ovarian cancer in one major counselling centre in Austria are at the core of this article. Our study investigates how people undergoing genetic testing try to make sense of this experience that is perceived to be new and uncommon in Austria and that is thus taking place in a setting not validated through public insurance support and is

Resolution of cell-mediated airways diseases

"Inflammation resolution" has of late become a topical research area. Activation of resolution phase mechanisms, involving select post-transcriptional regulons, transcription factors, 'autacoids', and cell phenotypes, is now considered to resolve inflammatory diseases. Critical to this discourse on resolution is the elimination of inflammatory cells through apoptosis and phagocytosis. For major in

Structure-based prediction of the effects of a missense variant on protein stability

Predicting the effects of amino acid substitutions on protein stability provides invaluable information for protein design, the assignment of biological function, and for understanding disease-associated variations. To understand the effects of substitutions, computational models are preferred to time-consuming and expensive experimental methods. Several methods have been proposed for this task in

Short-term prediction of influent flow rate and ammonia concentration in municipal wastewater treatment plants

The prediction of the influent load is of great importance for the improvement of the control system to a large wastewater treatment plant. A systematic data analysis method is presented in this paper in order to estimate and predict the periodicity of the influent flow rate and ammonia (NH3) concentrations: 1) data filtering using wavelet decomposition and reconstruction; 2) typical cycle identif

Bidirectional plasticity of purkinje cells matches temporal features of learning

Many forms of learning require temporally ordered stimuli. In Pavlovian eyeblink conditioning, a conditioned stimulus (CS) must precede the unconditioned stimulus (US) by at least about 100 ms for learning to occur. Conditioned responses are learned and generated by the cerebellum. Recordings from the cerebellar cortex during conditioning have revealed CS-triggered pauses in the firing of Purkinje

The handling of peripheral venous catheters - from non-compliance to evidence-based needs.

Aim. To study nurses' compliance to national guidelines (Sweden) for peripheral venous catheters and to establish the complication frequency connected to time in situ and bore size. Background. Worldwide, there are no standard peripheral venous catheters guidelines, and the need for elective replacement has been challenged. Furthermore, the time interval and need for elective change of peripheral

Diabetes Mellitus in Pancreatic Cancer and the Need for Diagnosis of Asymptomatic Disease.

Pancreatic cancer is strongly associated with the development of hyperglycemia, peripheral insulin resistance and diabetes mellitus, especially when presented as new-onset diabetes mellitus. Peripheral insulin resistance and hyperinsulinemia have been suggested to promote growth of pancreatic cancer cells, and therefore a relation between long-standing diabetes mellitus type 2 and pancreatic cance

Tissue-specific regulatory network extractor (TS-REX): a database and software resource for the tissue and cell type-specific investigation of transcription factor-gene networks.

The prediction of transcription factor binding sites in genomic sequences is in principle very useful to identify upstream regulatory factors. However, when applying this concept to genomes of multicellular organisms such as mammals, one has to deal with a large number of false positive predictions since many transcription factor genes are only expressed in specific tissues or cell types. We devel

The making of body differences: physical activity, gender, and age in institutional addiction treatment

Elements of sports and physical activity are common in institutional addiction treatment, in both Sweden and other European countries. These activities can be understood as activities of everyday life that promote health and well-being in institutional life. At the same time, physical activity is closely interwoven with a Western culture in which a healthy and fit body is an important social marke

Do circular economy business models capture intended environmental value propositions?

The circular economy (CE) can be a driver for sustainability and CE can be promoted and supported by the creation of new and innovative business models, which embed CE principles into their value propositions throughout the value chains. This study focuses on the environmental value propositions of the CE business models. The term environmental value proposition refers here to an absolute value be

Abdominal symptoms in general practice : Frequency, cancer suspicions raised, and actions taken by GPs in six European countries. Cohort study with prospective registration of cancer

Background Abdominal symptoms are diagnostically challenging to general practitioners (GPs): although common, they may indicate cancer. In a prospective cohort of patients, we examined abdominal symptom frequency, initial diagnostic suspicion, and actions of GPs in response to abdominal symptoms. Methods Over a 10-day period, 493 GPs in Norway, Denmark, Sweden, Belgium, the Netherlands, and Scotla

Local adaptation along an environmental cline in a species with an inversion polymorphism

Polymorphic inversions are ubiquitous across the animal kingdom and are frequently associated with clines in inversion frequencies across environmental gradients. Such clines are thought to result from selection favouring local adaptation; however, empirical tests are scarce. The seaweed fly Coelopa frigida has an α/β inversion polymorphism, and previous work demonstrated that the α inversion freq

Group-Sparse Regression : With Applications in Spectral Analysis and Audio Signal Processing

This doctorate thesis focuses on sparse regression, a statistical modeling tool for selecting valuable predictors in underdetermined linear models. By imposing different constraints on the structure of the variable vector in the regression problem, one obtains estimates which have sparse supports, i.e., where only a few of the elements in the response variable have non-zero values. The thesis coll

Composition of amino acids, fatty acids and dietary fibre monomers in kernels of Adansonia digitata and Sclerocarya birrea

There is increasing demand for sources of energy and non-meat protein with balanced amino acid profiles worldwide. Nuts are rich in protein and essential amino acids, and have a high energy value due to their high fat content. Kernels from two wild fruits in Mozambique, Adansonia digitata and Sclerocarya birrea, were selected for this study to determine their amino acid and fatty acid composition,

The effect of the pocket on the heat transfer of endwall with bluff body in the rear part of gas turbine

A pocket cavity is generated at the connection of two parts, such as the transition part between the low pressure turbine (LPT) and outlet guide vane (OGV) in a gas turbine engine. A bluff body, working as a heat transfer enhancement part or supporting strength part, has tremendous engineering applications in turbomachinery. In the present work, the effect of the pocket on the heat transfer of end

Major histocompatibility complex genes partly explain early survival in house sparrows

Environmental factors and genetic incompatibilities between parents have been suggested as important determinants for embryonic mortality and survival. The genetic set-up of the immune system, specifically the highly polymorphic major histocompatibility complex (MHC) may also influence individual resistance to infections. MHC proteins are important for an appropriate adaptive immune response and e

Can a teachable agent influence how students respond to competition in an educational game?

Learning in educational games is often associated with some form of competition. We investigated how students responded to winning or losing in an educational math game, with respect to playing with or without a Teachable Agent (TA). Students could choose between game modes in which the TA took a more passive or active role, or let the TA play a game entirely on its own. Based on the data logs fro

Landscape-scale interactions of spatial and temporal cropland heterogeneity drive biological control of cereal aphids

Agricultural landscapes are characterised by dynamic crop mosaics changing in composition and configuration over space and time. Although semi-natural habitat has been often shown to contribute to pest biological control, the effects of increasing landscape heterogeneity with cropland have been disregarded. Here, we examine how cereal aphids, their enemies and biological control are affected by th

Can the ego be depleted? : Attempts to replicate the ego depletion effect and integrate its explanations

Although self-control is so important that no one from any corner of the world would dispute, it is often difficult and vulnerable. Continuous exertion is one of the most influential factors that are detrimental to self-control, which leads to a state called “ego depletion”. Before 2016, the ego depletion effect had been a hot topic for a long time. After a multi-lab replication that reported a no