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A Population-Based Study on the Incidence, Risk Factors, and Outcome of Salmonella Bloodstream Infections in South Sweden 2012–2022

IntroductionInvasive infections caused by Salmonella are a significant global health concern. This population-based study aimed to comprehensively analyze invasive Salmonella infections in South Sweden, focusing on incidence, clinical presentation, risk factors, and outcomes.MethodsThis population-based observational cohort study, conducted from 2012 to 2022, included all patients with Salmonella

Perspectives on supervising and conducting interdisciplinary research projects

This study has been carried out as an assignment in the 2021 Readership Course (GB_S91) at LTH. The motivation for this study was to obtain a further understanding of the situation of PhD students and supervisors who operate in an interdisciplinary research context. The focus is on finding the positive aspects, as well as existing challenges, to comprehend how to provide future PhD students with a

Comparison of Airborne SARS-CoV-2 Omicron and Pre-Delta Variants Around Infected Patients

Transmissibility has increased during the evolution of SARS-CoV-2, possibly by improved airborne transmission. An increased transmission was noted also in many hospitals. We analyzed SARS-CoV-2 in room air of hospitalized Omicron infected patients and compared results with previous findings with pre-Delta variants to study if SARS-CoV-2 was more prevalent in patient rooms after the introduction of

From COPD epidemiology to studies of pathophysiological disease mechanisms : challenges with regard to study design and recruitment process: Respiratory and Cardiovascular Effects in COPD (KOLIN)

Background: Chronic obstructive pulmonary disease (COPD) is a largely underdiagnosed disease including several phenotypes. In this report, the design of a study intending to evaluate the pathophysiological mechanism in COPD in relation to the specific phenotypes non-rapid and rapid decline in lung function is described together with the recruitment process of the study population derived from a po

Engaging for Sustainable Development and Transformation – Exploring the Concept of Transformative Academic Institutions

Universities are expected to play a proactive role in the sustainable development andtransformation of their regions. However, they face external and internal barriers toplay that role. One possible approach to overcome those barriers is through trans-formative academic institutions (TAIs). TAIs are defined as research centres createdwithin universities to proactively engage in territorial develop

Aquaporin-3a Dysfunction Impairs Osmoadaptation in Post-Activated Marine Fish Spermatozoa

Spermatozoon volume regulation is an essential determinant of male fertility competence in mammals and oviparous fishes. In mammals, aquaporin water channels (AQP3, -7 and -8) have been suggested to play a role in spermatozoon cell volume regulatory responses in the hypotonic female oviduct. In contrast, the ejaculated spermatozoa of marine teleosts, such as the gilthead seabream (Sparus aurata),

Ischemic Stroke in Adults With Congenital Heart Disease : Cumulative Incidence and Associated Factors

BACKGROUND: When more patients with congenital heart disease reach adult age, increased incidence of long-term complications, including ischemic stroke, are expected. The aim of this study was to analyze cumulative incidence of ischemic stroke, associated factors, and case fatality in adult congenital heart disease. METHODS AND RESULTS: The study is based on Swedish national registers on congenita

Micro-costing of genetic diagnostics in acute leukemia in Sweden : from standard-of-care to whole-genome sequencing

Aims and background: Whole-genome sequencing (WGS) is increasingly applied in clinical practice and expected to replace standard-of-care (SoC) genetic diagnostics in hematological malignancies. This study aims to assess and compare the fully burdened cost (‘micro-costing’) per patient for Swedish laboratories using WGS and SoC, respectively, in pediatric and adult patients with acute lymphoblastic

Phonological influence in bilectal speakers of Brazilian and European Portuguese

Aims and objectives:This article investigates naturalistic acquisition of a second dialect (D2), comparing the global accent of speakers of Brazilian Portuguese (BP) exposed to European Portuguese (EP), either as children or as adults (early vs late bilectals). The focus is on the predicted advantage of an early age of onset of the D2, as well as possible crosslinguistic influence from the D2 onto

The Vitamin D Receptor as a Prognostic Marker in Breast Cancer-A Cohort Study

Previous research has indicated an association between the presence of the vitamin D receptor (VDR) in breast cancer tissue and a favorable prognosis. This study aimed to further evaluate the prognostic potential of VDR located in the nuclear membrane or nucleus (liganded). The VDR protein levels were analyzed using immunohistochemistry in tumor samples from 878 breast cancer patients from Lund, S

High cell density sequential batch fermentation for enhanced propionic acid production from glucose and glycerol/glucose mixture using Acidipropionibacterium acidipropionici

Background: Propionic acid fermentation from renewable feedstock suffers from low volumetric productivity and final product concentration, which limits the industrial feasibility of the microbial route. High cell density fermentation techniques overcome these limitations. Here, propionic acid (PA) production from glucose and a crude glycerol/glucose mixture was evaluated using Acidipropionibacteri

Experimental Investigation of Pilot Injection Strategies to Aid Low Load Compression Ignition of Neat Methanol

The growing demand to lower greenhouse gas emissions and transition from fossil fuels, has put methanol in the spotlight. Methanol can be produced from renewable sources and has the property of burning almost soot-free in compression ignition (CI) engines. Consequently, there has been a notable increase in research and development activities directed towards exploring methanol as a viable substitu

Exploring the use of innovation measurement in retail organisations : a multiple case study

Innovation and its management in retail organisations is an emerging field, yet the measurement of innovation in this context remains challenging and under-researched. The study investigates innovation in large Swedish retail companies, focusing on monitoring and measurement of innovation performance. Through a qualitative, multiple case study, our findings reveal that retailers are aiming to beco

Therapeutic window for nonerythropoietic carbamylated-erythropoietin to improve motor function following multiple infarct ischemic strokes in New Zealand white rabbits

Carbamylated erythropoietin (CEPO) is a novel neuroprotective agent that does not bind to the classical erythropoietin receptor or affect hematocrit. Since CEPO has not been systematically studied in a fully blinded and randomized manner in an embolic stroke model, we determined if CEPO would be useful to attenuate clinical deficits associated with multiple infarct ischemia using the rabbit small

Sense of coherence at work

The symposium addresses connections between Antonovsky’s Sense of Coherence-construct (SoC) and work experiences. A person with a high SoC perceives challenges as comprehensible, manageable, and meaningful; sense of coherence stands for a salutogenic disposition towards the world. Therefore, SoC may predict psychophysical health. The contribution of G. Larsson illuminates this by showing how poor

Some Aspects of Current Discourse on Knowledge Production and Knowledge Exchange between 'East' and 'West'

Increasing international and, often, cross-cultural contacts and exchanges in all spheres of human activity have created a world in which the access to other, alternative knowledge pools seems to be easier than ever before. Science in particular, or, more generally, fields of knowledge creation, are considered to have greatly benefited from this global inter-connectedness. At the same time, we can

Medverkan och inflytande : om brukarnas roll i socialtjänstens kunskapsutveckling

The main purpose of this essay was to study the program "Nationellt stöd för kunskapsutveckling inom socialtjänsten" ("National support for knowledge development within the social services") from the National Board of Health and Welfare on the basis of how such a development, as represented by the program, could affect clients' possibilities to participation and influence w

Anti-Incretin Gut Features Induced by Feed Supplementation with Alpha-Amylase : Studies on EPI Pigs

The acini-islet-acinar (AIA) axis concept justifies the anatomical placement of the Langerhans islets within the exocrine pancreatic parenchyma and explains the existence of the pancreas as a single organ. Amylase has been suggested to play a key role as an anti-incretin factor. Oral glucose tolerance tests (OGTT) were performed on 18 piglets in both a healthy (prior to pancreatic duct ligation (P

Refugee Labour Mobility to the EU: A Tool Contributing to Fairer Sharing of Responsibilities in the Context of Forced Displacement?

The idea of facilitating labour mobility for refugees as a pathway for admission is back on the policy agenda. Such complementary pathways are promoted in the Global Compact for Refugees as means to facilitate access to protection and solutions in addition to resettlement, and praised by United Nations High Commissioner for Refugees as directly contributing to easing pressure on host countries by