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Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy

Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,

TFPI-2 protects against gram-negative bacterial infection

Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac

Defining extended half-life rFVIII-A critical review of the evidence

Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient

Bacteria-immunoglobulin-lymphocyte interactions--new aspects

Of 30 bacterial species tested 18 stimulated DNA synthesis in human blood lymphocytes. The maximum response was after 3-4 days of culture suggesting a mitogenic effect. This was confirmed by the induction of polyclonal antibody production shown by a plaque assay. Most bacterial species increased the DNA synthesis in B-enriched lymphocytes and unseparated lymphocytes but had negligible activity on

C-terminal TFPI-1-derived peptides: their evolutionary host defense functions

Antimicrobial peptides (AMPs) are evolutionarily ancient molecules. They are essential innate immune response molecules that protect organisms from invading pathogens. Tissue factor pathway inhibitors (TFPI-1 and TFPI-2) C-terminal derived peptides exert host defense mechanisms against microbes. Studies showed that in human plasma, C-terminal TFPI-1 and -2 derived peptides mediate bacterial killin

Guidade visningar i appen

Botaniska trädgården har i samarbete med Visit Lund tagit fram tre olika guidade visningar i trädgården. Dessa kan du gå i egen takt. Du väljer själv om du vill lyssna på turerna eller läsa korta informationstexter. Turerna är följande: Utforska Botan: I denna visning kommer du att få utforska trädgården. Oavsett om du är trädgårdsentusiast eller bara nyfiken att uppleva något vackert, är denna vi

https://www.botan.lu.se/besok-och-program/guidade-visningar-i-appen - 2026-05-05

Inbjudan 10

Inbjudan.pdf Rättvisa i förmögenhetsrätten Affärsrättsligt Centrum vid Lunds universitet (ACLU) och forskningsavdelningen för allmän förmögenhetsrätt i Stockholm Centre for Commercial Law (SCCL) bjuder in till seminarium om I år är det 50 år sedan John Rawls gav ut ”A Theory of Justice”; ett bra tillfälle att ta upp ”rättvisa” i ett delsammanhang som rör juridiken och särskilt förmögenhetsrätten.

https://www.aclu.lu.se/sites/aclu.lu.se/files/2023-04/Inbjudan_10.pdf - 2026-05-06

Vacancy: Ledig tjänst som svensklektor vid universitet i Bukarest (RO)

Vacancy: Ledig tjänst som svensklektor vid universitet i Bukarest (RO) Vacancy: Ledig tjänst som svensklektor vid universitet i Bukarest (RO) Published 15 May 2025 Universitetet i Bukarest utlyser en ledig tjänst som svensklektor med tillträde från och med den 1 oktober 2025 till och med den 30 september 2026, med möjlighet till förlängning. Sista ansökningsdag är den 4 juni 2025. Share http://www

https://www.css.lu.se/article/vacancy-ledig-tjaenst-som-svensklektor-vid-universitet-i-bukarest-ro/ - 2026-05-04

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What a syllable can tell us on language Joana Rosselló joana.rossello@ub.edu University of Barcelona Language is a system of discrete infinity (DI). Any human being can cope with an infinite number of sentences (syntax) and chunks of well-formed sound/gesture sequences (phonology). Any human has also at his/her disposal an open-ended lexicon. In this paper I put forward the proposal that DI relies

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_glow36/Biolinguistics/What_a_syllable_can_tell_us_on_language.pdf - 2026-05-04

Protokoll Nämnden För GS 201126

Microsoft Word - Protokoll Nämnden för GS 201126.docx Graduate School Nämnden för Graduate School, 2020-11-26 Närvarande Ledamöter Mikael Sundström Studierektor, Graduate School Anne Jerneck Programansvarig, Development Studies Marta Kolankiewicz Programansvarig, Social Studies of Gender Rola El-Husseini Programansvarig, Middle Eastern Studies Annika Bergman Rosamond Programansvarig, Global Studie

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2020-12/Protokoll%20Na%CC%88mnden%20fo%CC%88r%20GS%20201126.pdf - 2026-05-06

Workshop: Turn your ideas into articles with The Conversation

28 april 2026 10:00 till 15:00 | Workshop Are you a researcher or a PhD student interested in reaching a global audience with your work? Lund University offers all its researchers the opportunity to share their research with the world through the international news platform, The Conversation. In this interactive workshop, The Conversation's science editor, Miriam Frankel, will guide you through Th

https://www.medarbetarwebben.lu.se/evenemang/workshop-turn-your-ideas-articles-conversation - 2026-05-06

About-coil-2021

Sida 1 av 4 Avdelning för internationalisering Externa relationer Isabelle Nilsson, projektassistent FÖRDELNING AV UTVECKLINGSMEDEL Datum 2021-05-24 Internationella rådet ombeds ta ställning till hur medel för COIL ska fördelas Lunds universitet. COIL vid Lunds universitet Av Kristina Eneroth och Ann-Kristin Wallengren Den fysiska mobiliteten har under det senaste pandemipräglade året till stora d

https://www.lusem.lu.se/internal/sites/lusem.lu.se.internal/files/2024-02/about-coil-2021.pdf - 2026-05-06

Inclusive Societies Archives - Page 10 of 10 - The Raoul Wallenberg Institute of Human Rights and Hu

Inclusive Societies Archives - Page 10 of 10 - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluatio

https://rwi.lu.se/category/inclusive-societies/page/10/ - 2026-05-04

Cliticisation in the acquisition of French as L1 and L2

The intense debate on continuity in child grammars has largely focused on the existence of Functional Categories (FCs) in early grammars despite differences in language use with adults (e.g., omissions, word order errors, lack of case marking). Simplified, the major theoretical explanations for these properties range from Maturational accounts (Radford 1990 and later) claiming an initial absence o

Nyhetsbrev Från GÅS-projektet Mars 2025

Nyhetsbrev från GÅS-projektet mars 2025 Professor Sölve Elmståhl har ordet Temat för detta nyhetsbrev är nya forskningsfynd i GÅS-studien. Show as web page I detta nyhetsbrev berättar vi om aktuella forskningsfrågor och resultat som utgår ifrån insamlade data från GÅS- projektet.  Fler projekt rör riskfaktorer för vanliga kroniska sjukdomar som nedsatt njur- och lungfunktion, högt blodtryck och på

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/2025-10/Nyhetsbrev%20fra%CC%8An%20GA%CC%8AS-projektet%20mars%202025.pdf - 2026-05-06