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Trends in type 1 diabetes incidence between 2007 and 2023 and their association with SARS-CoV-2 infection in a population-based matched cohort study among individuals under 30 years old in Sweden

AIMS/HYPOTHESIS: The incidence of type 1 diabetes increased during the pandemic in various countries. SARS-CoV-2 infections may trigger the development of type 1 diabetes, but the evidence is inconclusive. This study aimed to assess trends in type 1 diabetes incidence between 2007 and 2023, and to quantify the association between SARS-CoV-2 infections and the risk for developing type 1 diabetes.ME

Investigating the effect of adding comparisons with prior mammograms to standalone digital breast tomosynthesis screening

Purpose: The purpose is to retrospectively investigate how the addition of prior and concurrent mammograms affects wide-angle digital breast tomosynthesis (DBT) screening false-positive recall rates, malignancy scoring, and recall agreement. Approach: A total of 200 cases were selected from the Malmö Breast Tomosynthesis Screening Trial. They consist of 150 recalled cases [30 true positives (TPs),

Physical child abuse and self-reported health concerns : A case-control study including police-reported cases and unreported controls

BACKGROUND: Child abuse continues to pose a significant threat to children's health. The repercussions of abuse are profound, impacting the child's physical, social, and emotional well-being, with potential long-term effects that may extend into adulthood. To assist in identifying health concerns in children associated with exposure to physical abuse, a health questionnaire was developed to be use

Adjuvant Hyperthermic Intraperitoneal Chemotherapy in Patients With Locally Advanced Colon Cancer (COLOPEC) : 5-Year Results of a Randomized Multicenter Trial

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has

Occupational exposures to inorganic dust are associated with emphysema : the SCAPIS cohort

Objectives There is a lack of knowledge about whether occupational exposures increase the risk of emphysema, especially in never-smokers. Our objective was to determine if occupational exposures are associated with emphysema and impaired diffusing capacity. Methods In the Swedish CArdioPulmonary bioImage Study (SCAPIS), persons from the general population aged 50–64 answered a questionnaire and un

Challenges in population monitoring : Bar-tailed Godwits (Limosa lapponica) on the East Atlantic Flyway defy assumed population structure

Estimating and monitoring migratory bird populations involves significant challenges, even in the most well-studied and easily-counted species, and can be further complicated by long-held but unverified assumptions and by shifting distributions in changing flyway conditions. We illustrate these challenges using Bar-tailed Godwits Limosa lapponica on the East Atlantic Flyway. The subspecies L. l. l

Dynamic multi-layer Aerial system for latent diffusion-based Generative AI Inference at the Edge

In this paper, we investigate a Multi-layer Aerial system for GenAI inference at the Edge (MAGE). Therein, ground user equipments (UEs) request image synthesis services from a remote base station (BS) that leverages the Latent Diffusion Model (LDM) for image generation. Multiple Unmanned Aerial Vehicles (UAVs) are deployed to serve the UEs for relaying their images and prompts to the BS. To reduce

Participation in a digital self-management intervention for osteoarthritis and socioeconomic inequalities in patient-related outcomes

OBJECTIVE: To investigate changes in socioeconomic inequalities in patient-related outcomes and pain medication use, following participation in a digital self-management intervention for osteoarthritis (OA) in Sweden.METHOD: Participants with hip/knee OA enrolled in the digital intervention were included. Self-reported outcomes collected were the numerical rating scale (NRS) pain, activity impairm

Lifestyle and cardiovascular risk factors in a Swedish primary care population with self-reported psychiatric symptoms

Objective: Individuals with psychiatric illness suffer from poorer physical health compared with the general population and have a higher risk of developing cardiovascular and metabolic diseases. This cross-sectional study aims to describe the prevalence of lifestyle and cardiovascular risk factors and the association with self-reported psychiatric symptoms in a population of 40-year-old individua

Ceramides : a potential cardiovascular biomarker in young adult childhood cancer survivors?

Aims The aim of this study was to investigate circulating ceramides involved in cardiovascular disease (CVD) in young adult childhood cancer survivors (CCS) and their correlations to previously reported adverse cardiovascular changes in this cohort. Methods Fifty-seven CCS and 53 healthy controls (age 20-30 years) were studied. Plasma long-chain ceramides, known to be cardi- and results otoxic (C1

Dust source susceptibility in the lower Mesopotamian floodplain of Iraq

The identification of susceptible dust sources (SDSs) based on the analysis of effective factors (i.e. dust drivers) is considered to be one of the primary and cost-effective solutions to deal with this phenomenon. Accordingly, this study aimed to identify SDSs and delineate their drivers using remote sensing data and machine learning (ML) algorithms in a hotspot area in the Lower Mesopotamian flo

Functional properties of starch cultivars of two Andean grains grown in Bolivia: Amaranth (Amaranthus caudatus) and canihua (Chenopodium pallidicaule)

The functional properties of Andean grain starches of two species, amaranth (Amaranthus caudatus) and canihua (Chenopodium pallidicaule), three cultivars each, were studied. The study focused on chemical composition, pasting properties, thermal properties, water solubility index (WSI), swelling power (SP), and granule morphology. All amaranth starches were waxy starches, with amylose content le

The frequency of atrial fibrillatory waves is modulated by the spatiotemporal pattern of acetylcholine release : a 3D computational study

In atrial fibrillation (AF), the ECG P-wave, which represents atrial depolarization, is replaced with chaotic and irregular fibrillation waves (f waves). The f-wave frequency, F f, shows significant variations over time. Cardiorespiratory interactions regulated by the autonomic nervous system have been suggested to play a role in such variations. We conducted a simulation study to test whether t

Infective endocarditis after transcatheter aortic valve implantation : a nationwide study

AIMS : Transcatheter aortic valve implantation (TAVI), now a common procedure to treat high-risk patients with severe aortic stenosis, has rapidly been expanding into younger and lower-risk populations, creating a need to better understand long-term outcome after TAVI. The aim of the present investigation was to determine the incidence, risk factors for, clinical presentation of, and outcome after

Importance of potentially inappropriate medications, number of chronic conditions and medications for the risk of hospitalisation in elderly in Sweden : A case-control study

Objectives This study aimed to investigate the importance of potentially inappropriate medications, number of medications and chronic conditions for the risk of hospitalisation among an elderly population. Design This is a case-control study. Setting Population-based study in 2013 of all individuals aged 75 years and older (17 203) in the county of Blekinge in the southeast of Sweden. Participants

The Impact of Lake Water Quality on the Performance of Mature Artificial Recharge Ponds

Artificial groundwater recharge is commonly used for drinking water supply. The resulting water quality is highly dependent on the raw water quality. In many cases, pre-treatment is required. Pre-treatment improves the drinking water quality, although how and to what extent it affects the subsequent pond water quality and infiltration process, is still unknown. We evaluated two treatment systems b

Hippocampal single-voxel MR spectroscopy with a long echo time at 3 T using semi-LASER sequence

The hippocampus is one of the most challenging brain regions for proton MR spectroscopy (MRS) applications. Moreover, quantification of J-coupled species such as myo-inositol (m-Ins) and glutamate + glutamine (Glx) is affected by the presence of macromolecular background. While long echo time (TE) MRS eliminates the macromolecules, it also decreases the m-Ins and Glx signal and, as a result, these

Patient perspective in hereditary ataxia

Background: Hereditary ataxia is a group of rare disorders. Healthcareproviders and public authorities may have limited knowledge about thisdiagnosis. We asked the patients if they feel well-informed about thediagnosis and whom they usually turn to for support.Methods: Adult patients with a diagnosis of progressive cerebellar ataxiawere identified in the diagnosis register of Scania region or were

Safety of biological and targeted synthetic disease-modifying antirheumatic drugs for rheumatoid arthritis as used in clinical practice : Results from the ARTIS programme

Objective Longitudinal clinical registry-infrastructures such as Anti-Rheumatic Therapies in Sweden (ARTIS) allow simultaneous comparison of the safety of individual immunomodulatory drugs used in clinical practice, with consistent definitions of treatment cohorts, follow-up and outcomes. Our objective was to assess and compare incidence rates of key safety outcomes for individual targeted synthet

Research Paper Effectiveness of Group Training Based on Choice Theory on Internalizing Problems, Empathy, and Identity Transformations Among Male Adolescents

Background: Choice theory stems from psychological concepts like self-concept, successful identity, and quality of the world. The theory encourages adolescents to accept the responsibility for their choices on the one hand and predict the effect of such decisions on their lives on the other hand. The present study aimed to investigate the effectiveness of choice theory-based group training in inte