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Age estimation of wild boar (Sus scrofa) based on molariform mandibular tooth development and its application to seasonality at the Mesolithic site of Ringkloster
Localization of functional sites in the viral complement inhibitor KCP
Kaposi's sarcoma-associated herpes virus (KSHV) encodes a complement inhibitor named KSHV complement control protein (KCP). We have previously shown that KCP inhibits the human complement system by disrupting the C3 convertase of complement. KCP can accelerate the decay of the classical C3 convertase and it can act as a cofactor for factor I (R), which then cleaves and inactivates C4b or C3b (in t
NMR structure determination of proteins supplemented by quantum chemical calculations: Detailed structure of the Ca2+ sites in the EGF34 fragment of protein S
Amino Acid Oxidation of Candida antarctica Lipase B Studied by Molecular Dynamics Simulations and Site-Directed Mutagenesis
Molecular dynamics simulations have been performed on lipase B from Candida antarctica (CalB) in its native form and with one or two oxidized residues, either methionine oxidized to methionine sulfoxide, tryptophan oxidized to 5-hydroxytryptophan, or cystine oxidized to a pair of cysteic acid residues. We have analyzed how these oxidations affect the general structure of the protein as well as the
3-Alkyl- and 3-amido-isothiazoloquinolin-4-ones as ligands for the benzodiazepine site of GABA(A) receptors.
Metastatic sites and survival in lung cancer.
The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics
The recognition of carbohydrates by proteins is a fundamental aspect of communication within and between living cells. Understanding the molecular basis of carbohydrate-protein interactions is a prerequisite for the rational design of synthetic ligands. Here we report the high- to ultrahigh-resolution crystal structures of the carbohydrate recognition domain of galectin-3 (Gal3C) in the ligand-fre
Novel APC-cleavage sites in FVa providing insights into mechanisms of action of APC and its cofactor protein S.
EUCAARI ion spectrometer measurements at 12 European sites - analysis of new particle formation events
We present comprehensive results on continuous atmospheric cluster and particle measurements in the size range similar to 1-42 nm within the European Integrated project on Aerosol Cloud Climate and Air Quality interactions (EUCAARI) project. We focused on characterizing the spatial and temporal variation of new particle formation events and relevant particle formation parameters across Europe. Dif
Site Preference and Ordering Induced by Au Substitution in the γ-Brass Related Complex Au-Cr-Zn Phases.
Site-level model intercomparison of high latitude and high altitude soil thermal dynamics in tundra and barren landscapes
Ionization-site effects on the photofragmentation of chloro- and bromoacetic acid molecules
Simulation of CO2 and Attribution Analysis at Six European Peatland Sites Using the ECOSSE Model
Comparison of Methods to Obtain Force-Field Parameters for Metal Sites
Variability in exchange of CO2 across 12 northern peatland and tundra sites
Better constraints on sources of carbonaceous aerosols using a combined C-14 - macro tracer analysis in a European rural background site
Site-selective 13C labeling of histidine and tryptophan using ribose
Evaluation of δ13C in Carbonaceous Aerosol Source Apportionment at a Rural Measurement Site
The stable isotope of carbon, 13C, has been used in several studies for source characterization of carbonaceous aerosol since there are specific signatures for different sources. In rural areas, the influence of different sources is complex and the application of δ13C for source characterization of the total carbonaceous aerosol (TC) can therefore be difficult, especially the separation between bi
