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Simulation of stand transpiration based on a xylem water flow model for individual trees

Quantifying the water exchange between a forest stand and the atmosphere is of major interest for the prediction of future growth conditions and the planning of silvicultural treatments. In the present study, we address (i) the uncertainties of sap flow estimations at the tree level and (ii) the performance of the simulation of stand transpiration. Terrestrial laser scan images (TLS) of a mature b

Assessment of the genetic and clinical determinants of fracture risk : Genome wide association and mendelian randomisation study

Objectives To identify the genetic determinants of fracture risk and assess the role of 15 clinical risk factors on osteoporotic fracture risk. Design Meta-analysis of genome wide association studies (GWAS) and a two-sample mendelian randomisation approach. Setting 25 cohorts from Europe, United States, east Asia, and Australia with genome wide genotyping and fracture data. Participants A discover

Mortality and cancer incidence among secondary lead smelter workers

OBJECTIVES: To examine the mortality pattern and the cancer incidence in a cohort of long term smelter workers exposed to lead.METHODS: The cohort consists of 664 male lead battery workers, employed for at least three months in 1942-87. From 1969 the values of all blood lead samples repeatedly obtained from these workers every two to three months, have been collected in a database. The expected mo

Interpretation of variation in omics data : Applications in proteomics for sustainable agriculture

Biomarkers are used in molecular biology to predict characteristics of interest and are applied in agriculture to accelerate the breeding of target traits. Proteomics has emerged as a promising technology for improved markers by providing a closer view to the phenotype than conventional genome-based approaches. However, a major challenge for biomarker development is that the identified biological

Reliably predicting pollinator abundance : Challenges of calibrating process-based ecological models

Pollination is a key ecosystem service for global agriculture but evidence of pollinator population declines is growing. Reliable spatial modelling of pollinator abundance is essential if we are to identify areas at risk of pollination service deficit and effectively target resources to support pollinator populations. Many models exist which predict pollinator abundance but few have been calibrate

Thumb Base Osteoarthritis: Prevalence, Occupational Risk, and Surgical Outcomes

Osteoarthritis of the carpometacarpal joint at the base of the thumb (CMC1 OA) is common and causes difficulty in grasp, grip, and fine manipulation of the hand. Surgery is recommended after failure of non-operative treatment, andevidence from short and medium-term follow-up studies shows successful relief of pain and return of function. Previous investigations of epidemiology and risk factors wer

Smartphone Transnationalism in Non-Western Migration Regimes: Transnational Ethnography of Uzbek Migrant Workers in Russia

There is an extensive research that explores the reproduction of transnational communities and relations, with a particular focus on locality, identity and culture. However, the existing research emanates from the case studies of immigrant communities in Western-type democracies, while we know little about migrant transnationalism in non-Western migration regimes such as Russia, where migrant work

Insights into the Pu isotopic composition (239Pu, 240Pu, and 241Pu) and 236U in marshland samples from Madagascar

This work provides new insights into the presence of 239Pu, 240Pu, 241Pu, and 236U in the Southern Hemisphere through the study of peat bog cores from marshlands in Madagascar (19°S). 210Pb, 238Pu and 239+240Pu activities were characterized by alpha spectrometry in previous studies. Here, Pu from alpha-spectrometry discs corresponding to 10 peat-bog cores (85 samples) was reassessed for the aim of

Iron Deficiency in Left Ventricular Assist Device Recipients

PURPOSE: The prevalence of iron deficiency (ID) in Left Ventricular Assist Device (LVADs) recipients is not known nor has the association between ID and peak oxygen uptake (VO2) been reported. The aim of this study was to study to investigate the prevalence of ID in this population and the association between ID and VO2. METHODS: Data was included from LVAD recipients at Rigshospitalet, Denmark (D

Using geolocator tracking data and ringing archives to validate citizen-science based seasonal predictions of bird distribution in a data-poor region

Unstructured citizen-science data are increasingly used for analysing the abundance and distribution of species. Here we test the usefulness of such data to predict the seasonal distribution of migratory songbirds, and to analyse patterns of migratory connectivity. We used bird occurrence data from eBird, one of the largest global citizen science databases, to predict the year-round distribution o

Calculations of automatic chamber flux measurements of methane and carbon dioxide using short time series of concentrations

The closed chamber technique is widely used to measure the exchange of methane (CH4) and carbon dioxide (CO2) from terrestrial ecosystems. There is, however, large uncertainty about which model should be used to calculate the gas flux from the measured gas concentrations. Due to experimental uncertainties the simple linear regression model (first-order polynomial) is often applied, even though the

Chronic pain in older adults : prevalence, incidence, and risk factors

Objectives: Chronic pain is common in older adults, yet little is known of its development and the factors that predict its persistence and onset at old age. The aims of this longitudinal cohort study were to examine the prevalence and incidence of chronic pain and to explore possible risk factors for its persistence and onset in a representative sample of older Swedish adults. Method: Data were c

Migration Patterns of Nordic Greylag Geese Anser anser.

Migration patterns of Nordic Greylag Geese Anser anserwere studied by means of neck-collaring. A total of 4173birds (738 breeders, 1999 goslings and 1436 moulters;most moulters subsequently identified as belonging to aspecified breeding population) was marked throughoutNorway, Sweden, Denmark and Finland during 1984–1994. This report is based on observations made up to 30June 1995. In general, Nor

The presence of a short redox chain in the membrane of intact potato tuber peroxisomes and the association of malate dehydrogenase with the peroxisomal membrane

Peroxisomes and mitochondria were purified from potato tubers (Solanum tuberosum L. cv. Bintje) by differential centrifugation followed by separation on a continuous Percoll gradient containing 0.3 M sucrose in the lower half and 0.3 M mannitol in the upper half. The peroxisomes band at the bottom and the mitochondria in the middle of this type of gradient. Mitochondrial contamination of the perox

Genetic variation at 16q24.2 is associated with small vessel stroke

Objective: Genome-wide association studies (GWAS) have been successful at identifying associations with stroke and stroke subtypes, but have not yet identified any associations solely with small vessel stroke (SVS). SVS comprises one quarter of all ischemic stroke and is a major manifestation of cerebral small vessel disease, the primary cause of vascular cognitive impairment. Studies across neuro

Microarray-based Analyses of Hypoxia-induced Transcriptional Changes in Breast Cancer Cell Lines

Background: Tumour hypoxia is a common characteristic of many solid human tumours, and is associated with a poor prognosis in various types of cancer. Metabolic changes occur when cells are exposed to low oxygen pressure; however, little is known about the mechanisms underlying malignant transformation and/or progression caused by hypoxia. Materials and Methods: We monitored global gene expression

Low-Level Cadmium Exposure Is Associated with Decreased Bone Mineral Density and Increased Risk of Incident Fractures in Elderly Men: The MrOS Sweden Study.

One risk factor for osteoporosis which has attracted increasing attention in recent years is exposure to cadmium. The aim of this study was to examine the associations between low-level cadmium exposure, from diet and smoking, and BMD and incident fractures in elderly men. The study population consisted of 936 men from the Swedish cohort of the MrOS study, aged 70-81 years at inclusion (year 2002-

Candidate gene analysis and exome sequencing confirm LBX1 as a susceptibility gene for Idiopathic Scoliosis.

Idiopathic Scoliosis is a spinal deformity affecting approximately 3% of otherwise healthy children or adolescents. The etiology is still largely unknown but has an important genetic component. Genome-wide association studies (GWAS) have identified a number of common genetic variants that are significantly associated with idiopathic scoliosis in Asian and Caucasian populations, rs11190870 close to