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Extraskeletal myxoid chondrosarcoma (EMC) is a soft-tissue neoplasm cytogenetically characterized by the translocations t(9;22)(q22;q11-12) or t(9;17)(q22;q11), generating EWS/CHN or RBP56/CHN fusion genes, respectively. In the present study, 18 EMCs were studied both cytogenetically and at the molecular level. Chromosomal aberrations were detected in 16 samples: 13 with involvement of 9q22 and 22

Smoking has recently been recognised as causally associated with the development of gastric cancer (GC). However, evidence on the effect by sex, duration and intensity of smoking, anatomic subsite and cessation of smoking is limited. Our objective was to assess the relation between tobacco use and GC incidence in the European Prospective Investigation into Cancer and Nutrition (EPIC). We studied d

To investigate if karyotypic features of secondary liver tumors may provide diagnostic information and if the cytogenetic patterns of primary and metastatic colorectal carcinomas (CRC) are different, 33 liver metastases were analyzed: 25 CRC, 4 small intestine carcinoids, 1 ovarian carcinoid, 1 lobular breast cancer, 1 head-and-neck squamous cell carcinoma, and 1 uveal malignant melanoma. Chromoso

This paper investigates the greenhouse gas emissions from a Swedish wetland, constructed to decrease nutrient content in sewage treatment water. To evaluate the effect of the construction in terms of greenhouse gas emissions we carried out ecosystem-atmosphere flux measurements of CO2, CH4 and N2O using a closed chamber technique. To evaluate the importance of vascular plant species composition to

The history of spinal cord injuries starts with the ancient Egyptian medical papyrus known as the Edwin Smith Surgical Papyrus. The papyrus written about 2500 B.C.by the physician and architect of the Sakkara pyramids Imhotep, describes "crushed vertebra in his neck" as well as symptoms of neurological deterioration. An ailment not to be treated was the massage to the patients at that time. This f

The recent introduction of entry inhibitors in the clinic as components of antiretroviral treatment has heightened the interest in coreceptor use of human immunodeficiency virus type 1 (HIV-1). Viruses using CCR5 as coreceptor (R5 viruses) are generally present over the entire course of infection whereas viruses using the CXCR4 coreceptor (R5X4/X4 viruses) emerge in about 50% of infected individua

Popular Abstract in Swedish Miljontals fåglar lämnar Sverige varje höst för att övervintra på sydligare breddgrader och återvänder nästkommande vår för att föda upp sina ungar på de enorma mängder insekter som finns här tack vare det tempererade klimatet. Småfåglar genomför sin flytt etappvis genom att flyga ett antal dagar eller nätter i sträck, beroende på om fågeln är en dag- eller nattsträckar

Popular Abstract in English Oil resources are finite; and political and economic factors affecting oil production,together with the environmental damage associated with the increased use of oil by a rapidly growing population, have underscored the need for developing cleaner technologies based on sustainable resources. In this context, any lignocellulosic biomass that is not used in the food chainThe present work was aimed at developing industrial S. cerevisiae strains with improved tolerance to two types of stressors encountered during the fermentation of lignocellulosic biomass that affect ethanol yield and productivity, namely hydrolysate-derived inhibitors and high temperature, and at understanding the response of yeast and mechanisms of adaptation to such stressors. In one part of the

The European Spallation Source (ESS) is the European common effort in designing and building a next generation large-scale user facility for studies of the structure and dynamics of materials. The proposed schematic layout of the ESS facility is based on a linear driver (linac) directing the proton beam (5 MW of 2.5 GeV) of 2.8 ms long pulses with a 20 Hz on a tungsten target where neutrons are pr

Background The pattern of cancer in long-term survivors from childhood cancer has not been investigated comprehensively. Methods We obtained a cohort of 47 697 children and adolescents aged 0-19 years with cancer as defined by the country-wide cancer registries of Denmark, Finland, Iceland, Norway, and Sweden during 1943-2005. Cohort members were followed through age 79 years for subsequent primar

Degrowth is an academic concept and activists' niche project in Europe and other early-industrialized parts of the world aiming to reframe the current sustainability challenge of declining environmental and unjust social conditions. Its emphasis is on the radical transformation of the current societal-economic structure in order to achieve inherently sustainable conditions. There are various d

The expansion of Swedish wind energy grid has come at the cost of environmental, economic and social controversy, in which the issue of landscape quality change plays a prominent role. Tourism, an industry highly reliant on visual consumption of the landscape, is especially sensitive to this change. Scholars have repeatedly harvested evidences of a weak, but negative correlation between wind power

Haloacid dehalogenase (HAD)-like hydrolases represent a vast superfamily characterised by their ability to form covalent enzyme-substrate intermediates facilitating the cleavage of C-Cl, C-P, or CO-P bonds. Within this work one member of this superfamily, HAD from Thermotoga neopolitana (HADTn) exhibiting a phosphatase (P-O bond cleavage) like activity was investigated in the context of altering t

Doftreceptor Or22a och dess betydelse för äggläggning hos bananflugor Vanliga bananflugor har länge använts som testorganismer inom biologisk forskning, så som neurobiologi. Anledningen till detta är att de har ett nervsystem som är lättillgängligt men enklare uppbyggt än däggdjurs (Stocker, 1994,). Luktsinnet hos bananflugor sitter i antennerna och i de maxillära papillerna, som sitter vid flugaThe fruit fly Drosophila melanogaster has a well-studied olfactory system. A crucial part of the olfactory system is the olfactory sensory neurons (OSNs). One type of these OSNs, Ab3a, expresses the Odor receptors (ORs) Or22a and Or22b. Or22a is known to play an important role for behaviors like oviposition, but no strong ligand has been found for Or22b. Recent studies have shown that D. melanogas

Kol har lagrats is torvmarker i tusentals år och idag innehåller torvmarkerna ca en tredjedel av all markkol på jorden. Det råder stor osäkerhet hur torvmarker kommer att reagera på klimatförändringar. Detta beror på att de kalla, blöta och syrefattiga förhållandena leder till motsatta effekter för global uppvärmning; dels lagras koldioxid eftersom fotosyntesen är större än respirationen (kylande Northern peatlands have accumulated carbon for thousands of years and currently hold around one third of all soil carbon on earth. Large uncertainties are associated with predictions of how northern peatlands will react to climate change. This is because the cold, wet and anaerobic conditions lead to two opposing forces from a radiative forcing perspective – CO2 sequestration from photosynthesis b

Background: Knowledge sharing within an organization is one of the main focuses of the knowledge management research field. In today’s globally dispersed business units, and multinational corporations (MNCs), information and communication technology (ICT) tools play an essential role in facilitating knowledge sharing. Previous research has argued the vital role informal contexts as well as physica

While renewable energy output in the World increases, Russia shows an opposite trend, consisting of a highly engrained fossil fuel-driven economy with very little State priority towards diversifying its energy supply. Accordingly, although wind energy represents only a niche market, it is more economically viable to electrifying Northern peripheral communities than connecting them to the national